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PERSPECTIVE article

Front. Psychiatry, 18 October 2019
Sec. Forensic Psychiatry

Perspective On Excellence in Forensic Mental Health Services: What We Can Learn From Oncology and Other Medical Services

Harry G. Kennedy,*&#x;Harry G. Kennedy1,2*†Alexander Simpson&#x;Alexander Simpson3†Quazi Haque,Quazi Haque4,5
  • 1Department of Psychiatry, Trinity College Dublin, Dublin, Ireland
  • 2National Forensic Mental Health Service, Central Mental Hospital, Dundrum, Dublin, Ireland
  • 3Division for Forensic Psychiatry—University of Toronto Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada
  • 4Elysium Healthcare, London, United Kingdom
  • 5Division for Forensic Psychiatry—University of Toronto Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health—University of Toronto, Toronto, ON, Canada

We propose that excellence in forensic and other mental health services can be recognized by the abilities necessary to conduct randomized controlled trials (RCTs) and equivalent forms of rigorous quantitative research to continuously improve the outcomes of treatment as usual (TAU). Forensic mental health services (FMHSs) are growing, are high cost, and increasingly provide the main access route to more intensive, organized, and sustained pathways through care and treatment. A patient newly diagnosed with a cancer can expect to be enrolled in RCTs comparing innovations with the current best TAU. The same should be provided for patients newly diagnosed with severe mental illnesses and particularly those detained and at risk of prolonged periods in a secure hospital. We describe FMHSs in four levels 1 to 4, basic to excellent, according to seven domains: values or qualities, clinical organization, consistency, timescale, specialization, routine outcome measures, and research. Excellence is not elitism. Not all centers need to achieve excellence, though all should be of high quality. Services can provide each population with a network of centers with access to one center of excellence. Excellence is the standard needed to drive the virtuous circle of research and development that is necessary for teaching, training, and the pursuit of new knowledge and better outcomes. Substantial advances in treatment of severe mental disorders require a drive at a national and international level to create services that meet these standards of excellence and are focused, active, and productive to drive better functional outcomes for service users.

Introduction

Forensic mental health services (FMHSs) provide treatment for persons with severe and disabling mental disorders in conditions of therapeutic safety and security. Typically, patients are admitted to forensic services and forensic hospitals from other hospitals, the community, or the criminal justice system because of violent behavior toward others and undergo relatively prolonged, intensive, and restrictive care and treatment (1, 2). By forensic services, we are referring to a therapeutically safe mental health service to a selected population, not only forensic hospitals but also integrated, coordinated systems of care across the interface of criminal justice and mental health services. FMHSs are high cost, low volume, and high risk and must therefore yield high value in health gains. The delivery of clinical services for persons with severe and enduring mental illness is poorly organized, and standards of practice are highly variable. Care can be inconsistent, with variation in standards and in models of care. Best evidence is not routinely implemented. Other parts of the health sector have been more effective at implementing consistent service standards, including treatment as usual (TAU) linked to clinical trials and service research aimed at driving improvement. Quality programs are necessary to ensure that services meet a minimum standard (36). Other health services (for example, surgery, oncology, obstetrics) have adopted systems that greatly enhance quality and also continuously improve outcomes for patients through promotion of an academic mission.

This paper describes how excellence can be recognized from the ability to conduct randomized controlled trials (RCTs) (7) and information-driven research paradigms which may be “hypothesis free” (8) or mix quantitative and qualitative methods so as to continuously improve TAU. This is set out with particular reference to FMHS for persons presenting serious risk to others (9), since FMHSs increasingly provide the main access route to more intensive, more organized, and more sustained pathways through care and treatment (10). In FMHS, TAU has been inadequately defined. Scientific evidence is limited for many key practices and interventions (1114), presenting challenges for the delivery of better outcomes. We will relate this system for describing excellence to the tiers of clinical organization that exist in mental health services generally. FMHS can be structured in a population-based and tiered way to ensure high quality of care through coordinated, robust TAU and continuously improving outcomes through academic leadership of services that promote excellence through research, evaluation, and dissemination of improving clinical standards.

Cancer services provide a model for tiered, population-based specialist care and treatment for serious disorders with some centers of excellence driving the acquisition of new knowledge and better outcomes. A newly diagnosed patient may present to any specialist cancer service and expect evidence-based, systematically implemented, and effective TAU, tested and validated by RCTs, e.g., Giacchetti et al. (15).

With such well-established TAU in cancer services, it is common for newly diagnosed patients to be offered enrolment in international multicenter RCTs comparing TAU with new treatments organized by not-for-profit research cooperatives (1619).

Like oncology services, FMHSs also treat people with severe illnesses that require consistent, coordinated care pathways and would benefit greatly from this structure of service organization. In this paper, we will describe an organizing framework based on excellence, to advance these ends.

A Framework to Improve TAU and Achieve Excellence

FMHSs are not as well structured as cancer services when it comes to systematically defined evidence-based treatments, nor for tiered structure and expectations of services. It is notable that there are few high-quality studies of even basic pharmacological interventions for acute psychoses with disturbed behavior (20, 21). It may be argued that psychiatric patients and problems are too complex, and results are too difficult to generalize from RCTs, but these problems can be overcome (22). RCTs are possible for clinically and legally complex non-pharmacological, systemic interventions (2326) including FMHS (2731), although the ethical difficulty of producing such studies in a forensic setting is recognized (3234). This suggests that a new organizing framework is needed.

A structured approach is required to frame service expectations, organization, and values. To achieve this, we propose that clinical quality of forensic psychiatric hospital services should be classified hierarchically. This does not imply a value judgment. Although expressed in terms of a hierarchy, each level includes and builds on the previous levels. Patel et al. (35) suggest that the highest level of “excellence” in relation to clinical services may be taken to mean “outstanding fitness for purpose and surpassing ordinary standards through deliberate practice.” In clinical services, this is true at the level of lead practitioners when related to expertise (36) and at the level of institutional culture (37).

We propose that services can be divided into four broad levels of organization and complexity and can be described by seven domains or qualities (see Table 1). Level 1 corresponds to individual practitioners or independent expert clinical groups. Level 2 describes local multidisciplinary teams (MDTs) or groups of services. Level 3 refers to integrated community and hospital services with a broad service mandate, and Level 4 refers to academically led and productive centers of excellence. The seven domains characterizing these levels have been derived from formats or structures for models of care (35) and process mapping (38). The domains are a) values and rights, b) clinical organization, c) consistency, d) timescale, e) specialization, f) routine outcome measures, and g) research and development. We suggest that this approach is relevant to models of care at the systems and population level, and such models of care (35) describe existing structures, processes, and values as a general system (39). These elements of models of care can be distinguished from broader conceptual or professional models such as the bio-psychosocial model (40, 41). A model of care is distinct from such models (42) and may be thought of as elements of a meta-model for systems addressing larger populations and across cultures (4345).

TABLE 1
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Table 1 Framework for Health Sector Organization to Promote Excellence.

Because complex interventions (46) are required for severe and enduring mental illnesses (SEMIs), Levels 1 and 2 described here may provide services such as primary health care services to persons with SEMI but are unlikely to have a major place in FMHS for severe mental illnesses except when subsumed within Level 3 or 4 services. This integration is itself an enhanced level of integrated and coordinated systems across criminal justice, mental health, and other social institutions and services (47). Prison in-reach and court diversion services provide frontline services typically with systematic screening for severe mental illness (48) and diversion from the criminal justice system (4952) including youth justice (53) but typically are organized at a regional level and have characteristics of and are integrated with at least tier 3. Impact evaluations of tier 1 forensic services such as street and police station diversion are rare, with benefits emerging when mixed methods participant-action research approaches are adopted in tier 2 or 3 services to modify models of care and systematically evaluate impact and health benefits across a defined population (47, 50, 5355). The achievement of high quality in the provision of TAU is the primary goal of Level 3 services. The advancement of new knowledge, interventions, and services to improve outcomes is the mission of Level 4 services (see Table 1).

Seven Domains

The characteristics of each domain are now described.

1. Values and Rights

Services provided at Level 1 value individual practice styles governed by rules of professionalism. At Level 2, services value consistency in professionalism, through a combination of education, specialist training, experience, and patient-centered ethics. This generates expertise, typically regulated by professional registration. At Level 3, welfare rights are emphasized requiring services that have the competencies of Level 2 but are also consistent, accessible, rights-based, and evidence based to meet the complex needs of patients and populations. Such centers are subject to service accreditation by a national regulatory body. At Level 4, services further value research, development, and the dissemination of the best “TAU.” This requires academic resources and skills leading to a cycle from research to development, to teaching and training staff for all levels of service, which forms the basis for further acquisition and dissemination of new knowledge. Academic league tables (5659) or citation indices (60) may be a guide to achievement in this domain. Mechanisms also exist for crediting cultural appropriateness, community change, and innovation (6163).

2. Clinical Organization

At Level 1, each professional discipline acts independently of each other. At Level 2, disciplines organize into multidisciplinary teams with leadership typically by the legally responsible psychiatrist. At Level 3, governance systems operate to ensure continuous improvement in quality, ensuring that a minimum standard is reached by all (35). Usually this is formulated in a written model of care (38, 46). This should include a description of recovery pathways through care and across services and organizations, for example, from the criminal justice system to FMHS and on to the community (1, 2), including integrated expert systems of care (47). At Level 4, Level 3 systems are expanded to embrace national and international networks for cooperation (64) as well as organization into academic networks to improve effectiveness and run multicenter research studies.

3. Consistency

At Level 1, consistency is valued less than individual clinical wisdom. At Level 2, consistency applies only within teams with some consistency through the use of international diagnostic systems and manualized treatment programs. At Level 3, hospital or service-wide governance is applied to essential decision making and processes such as applying admission criteria by admission panels (6569), to plan care pathways across the service, with evidence-based decision making on matters such as care systems (7073), leave (74, 75), and reports to mental health review tribunals (7678). At Level 3, precision medicine can be practiced with diagnosis refined into the staging of progression of illnesses and outcomes (79). At Level 4, precision medicine is likely to be enhanced over time by the investigation of personalized medicine (8) including the development of transdiagnostic systems for diagnosis and treatment based on causal factors such as neuroprogression, neuropsychological, and genetic profiles (8083).

4. Timescale

At Level 1, interventions are delivered only on a day-to-day basis. At Level 2, it is possible to organize interventions week to week, corresponding to the pattern of working of an individual multidisciplinary team. At Level 3, it is possible to organize individual treatment plans and care pathways into service-wide programs delivered according to monthly, quarterly, or annual cycles. At Level 4, it is possible to prepare, deliver, and evaluate 5-year plans for service level quality improvement and for translational work from laboratory to clinic (84).

5. Specialization

At Level 1, specialization is dependent upon how each clinician acts in relation to the uniqueness and autonomy of each individual patient. At Level 2, small specialist units can be developed based on fundamentals such as gender, diagnostic category, or levels of therapeutic structure and support such as levels of therapeutic security (1, 2). At Level 3, it is possible to organize delivery of care and treatment according to stratified care pathways matching needs into acute and sub-acute treatments, medium-term intensive treatments, or longer-term slow-stream treatments (1, 2, 85). This aims to target specific elements responsible for pathology in a given person at a given time within the limits of precision medicine. At Level 4, multimodal TAU can be defined, developed, delivered, and evaluated (86) in research paradigms. These aspire to the investigation of personalized medicine as and when molecular (81, 83), imaging (87, 88), and lifestyle data become available and amenable to individualized use.

6. Routine Outcome Measures

At Level 1, only qualitative assessment is possible. At Level 2, only dynamic assessment of risks and needs can be assessed over time. At Level 3, functional outcomes can be assessed at regular intervals and linked to evidence-based governance reporting (89). At Level 4, systematic routine outcome measurement becomes normal and is organized as part of service governance and decision making (57). Level 4 services will typically have inter-operable data platforms to allow benchmarking of outcomes on a condition-by-condition basis across a whole cycle of care (89, 90). Routine outcome measures may be organized independently of treating clinicians and blind to interventions at the psychometrics laboratory level, as would be the case in an RCT, or any general medical or surgical hospital.

7. Research

At Level 1, only individual case studies are possible. At Level 2, limited case series are possible (91, 92). At Level 3, retrospective and prospective observational cohort studies become possible (9395), developing precision medicine. At Level 4, population-based samples for informatics research (8, 96) and multicenter randomized controlled trials or systematic reviews of treatment trials (9799) become integrated into systematic treatment along with population-based epidemiological studies as they relate to diagnosis and prediction (100, 101), levels of emergence in personalized approaches (102), and services at a national level (103). At this level, translational research is possible concerning fundamental discovery at the level of molecular, imaging, psychosocial, or epidemiological personalized medicine, from bedside to clinical trials of applications, from translation to policy and health care guidelines, with later assessment of health policy and usage, locally and internationally (84).

Application to FMHS

FMHSs lend themselves very well to this form of analysis. Like cancer services, they deal with clinical disorders that are potentially life threatening, expensive, and safe if carefully delivered. Services are typically organized in tiers according to the size of the population served. Second-tier services (analogous to Level 3) are provided for populations of approximately 250,000 to 300,000, tertiary services (which should aspire to be Level 4 services) for 3 to 5 million, fourth-tier services for highly specialized sub-populations, and in some large centers, highly specialized services for populations of 20 to 50 million (1, 2, 85).

This population tiering should also be related to quality and excellence, but often, this is not the case. In other areas of clinical practice, it has been shown that a minimum level of experience is required for acceptable outcomes per procedure (104106), and a minimum volume of new cases is required to maintain both expertise and training functions in many areas of practice (107111). This results in benefits measured in mortality and side effects even when adjusted for case mix (112, 113). Alternatively, networks of expertise—a different model for delivering centers of excellence—appear to have a positive effect on quality of care if they have adequate resources, credible leadership, efficient management, effective communication, and collaborative, trusting relationships, though the evidence for this is weak (114).

Psychiatric practice should currently be at the level of precision medicine at least in part. Precision medicine (81, 115) is defined as relating to the staging (8083) and stratification of subgroups of populations for diagnosis, treatment, or prevention, which may result in the targeting of specific elements responsible for pathology in any given person at a particular time (80). This includes the use of diagnostic tests or staging tools for stratification based on the risk of disease or response to treatment (53). These techniques include the structured professional judgment instruments commonly used in forensic mental health such as risk assessment, assessment of functional mental capacity, and triage for stratified therapeutic security (116119). FMHSs are generally already practicing precision medicine in relation to staging and stratification, though progress is gradual to date in some areas of research (88). Our position is that it is now possible to begin moving toward personalized medicine, as all other areas of practice do so, and that FMHSs are well placed to make this move.

We have cited several studies in which the measurement of complex TAU has been related to personal recovery (78), functional recovery including moves to less secure places and conditional discharge (70, 77) including an RCT (31), and stratification (71, 72), as has been recommended elsewhere (89, 90).

RCTs should be widely used to assess and improve interventions and outcomes in mental disorders and could flourish in the structure proposed here. Interventions for rehabilitation and recovery including violence reduction and prevention in schizophrenia and other mental disorders are multimodal (120). The best evidence for effectiveness in mental health interventions arises from common factors such as therapeutic rapport, working alliance, and motivation (121). Complex interventions are increasingly recognized as amenable to study. Complex interventions are central to an understanding of TAU in randomized controlled trials of psychological treatments in fields such as oncology (122). In FMHS, models of care divide broadly into a standard model of stratified therapeutic security (1, 2) with parallel pathways for special groups and non-stratified units for special subgroups. Comparisons of models of care (24), legal interventions (23, 25), and complex interventions such as integrated care pathway approaches are themselves amenable to randomized controlled trials and systematic study (26).

The EU Joint Programme—Neurodegenerative Disease Research (JPND) (115) provides another example of a system of standards that could be relevant to disabling mental illnesses such as schizophrenia. The large variability in neurodegenerative disorders represents a major impediment to finding optimized approaches to care. Deciphering this variability is therefore necessary. The Horizon 2020 advisory group put forward personalized medicine as a model that uses characterization of individual phenotypes and genotypes (molecular profiling, imaging, and lifestyle data) to tailor the correct individual therapeutic strategy, determining the predisposition to disease, or to deliver timely and targeted prevention (123, 124). The JPND is a trans-national network that is an exemplar of the type of initiative that could substantially improve outcomes for the patients of FMHS.

Discussion

The most cogent criticisms of FMHSs are not simply debates about the ethics of compulsion but criticisms of effectiveness, and these are based on the absence of RCT studies relevant to the field (14). We have described guiding principles to organize levels of practice within FMHS that will facilitate the development of TAU. All FMHSs could function at what we describe as Level 3, linking to Level 4 FMHSs that are in turn part of national or international networks. A working example can be found in the Scottish FMHSs managed care network (forensic network) established in 2003 (125) and the Expertisecentrum Forensische Psychiatrie in Utrecht, Netherlands (126). We believe there are other informal networks of this type in existence, and organizations such as the International Association of Forensic Mental Health Services encourage such integration of knowledge and service advancement.

The levels described here are not the same as the tiers often described as ways of organizing mental health services according to population size (127, 128). Nor are these levels the same as the tiers of specialization and sophistication for the delivery of more complex interventions. Mental health interventions range from widespread and basic programs for simple or minor problems to more complex care plans and intensive, prolonged interventions for selected patients with disabling or high-risk disorders (128131). This descriptive system for levels of quality and excellence is compatible with the organization of services into tiers, commencing with basic interventions for minimally disabling disorders affecting a wide population base and increasing to specialized interventions for those with more severe and complex needs. Treatment may reduce levels of dependency, though in the present state of knowledge, evidence that mental health services for severe and disabling mental illnesses lead to improved functional outcomes is limited (132).

Academic center affiliates should deliver “excellent” treatment at Level 4. Setting quality standards and guidelines for TAU is primarily an activity of Level 4 services working in networks which include Level 3 services.

Level 4 FMHS should be peer-reviewed and accredited. This should be both national and international in order to develop the networks needed to foster multicenter RCTs and data-driven research on outcomes. Some national networks for quality and accreditation already exist, such as the quality networks in the UK (34, 5, 9) and the Netherlands (6). Up until now, these have focused on raising the minimum standard and fostering consistency. We believe such networks can better drive excellence by moving from primarily judging compliance with standards and guidelines to also accrediting quality improvement by services using research-informed outcome measurement and management (9, 133). International networks such as the International Association of Forensic Mental Health Services, European Psychiatric Association, and World Psychiatric Association are also focused on these goals. The ambition should be to emulate what has been achieved by cancer research networks (1619) and networks in other areas (134).

Characteristics described for Level 4 excellence would be regarded as standard in most oncology services. There are very few such excellent services available for people with disabling mental illnesses and disorders. There is no reason why this should not now be possible. Much of the infrastructure for Level 4 services already exists in FMHS organized at regional and national levels. We believe that in general, most such services are operating or can operate at Level 3, but often with inadequately defined TAU and models of care. It is now possible to ensure that TAU is consistent, evidence based, and improving through international cooperation, when also adapted thoughtfully to local population needs.

We are concerned with systemic ways of improving measurable “real-world” outcomes such as survival, personal recovery and hope, symptomatic recovery, functional recovery, recovery of autonomy and responsibility (forensic recovery), and reduced length of stay. We have presented a detailed analysis of research literature on how these fundamentals have improved markedly in other areas of clinical practice, notably oncology but also obstetrics and surgery. We have drawn attention to the disappointing lack of progress in these domains in services for the most severely mentally ill. We have extensively cited RCTs of psychological and psychosocial interventions in forensic psychiatry (2734), while noting how sparse these are (1214). We believe that the addition of mixed methods to study “soft” or “subjective” outcomes is also important (78, 89), and these are useful insofar as they contribute to improving such outcomes as survival, earlier discharge from secure places (77), reduced risk of violence (86, 93, 94, 96, 97, 99, 120) and suicide (103), or improved function (86, 89).

We have reviewed the viability of RCTs for complex interventions in psychiatry (7, 22). Manualization is no longer regarded as the most effective aspect of delivering larger effect sizes with fidelity to the treatment modality (121). Real-world data analytic studies may be a better approach to identifying what may be effective (8, 87, 101, 102, 124). RCTs in psychiatry will require the capacity to quantify complex TAU (32), and this will depend on aggregation of measures (77, 78, 86, 116119). In detecting treatment effects, it is important to use measures that are calibrated in units of meaningful change rather than arbitrary units, an approach that is uniquely possible in forensic services (119).

It is notable that some of the best models or meta-models for psychiatric care omit references to FMHS and excellence (135, 136). This can be contrasted with recent recognition of the interconnectedness of general adult and forensic psychiatric services and pathways (137). We propose that advances in the treatment of the more severe mental disorders require a drive at a national and international level to create forensic psychiatry centers of excellence. Services that are focused, active, productive, and excellent are required in order to drive better outcomes for service users.

Ethics Statement

The authors assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional committees on human experimentation and with the Helsinki Declaration of 1975, as revised in 2008, and the authors assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional guides on the care and use of laboratory animals.

Author Contributions

HK, AS, and QH contributed conception and design of the study. HK wrote the first draft of the manuscript. All authors contributed to manuscript revision, read and approved the submitted version.

Conflict of Interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Acknowledgments

The authors acknowledge the experience of working in forensic psychiatry in many settings for many years and discussing the nature of this work with colleagues and commissioners.

References

1. Kennedy HG. Therapeutic uses of security: mapping forensic mental health services by stratifying risk. Adv Psychiatr Treat (2002) 8:433–43. doi: 10.1192/apt.8.6.433

CrossRef Full Text | Google Scholar

2. Kennedy H, Castelletti L, O’Sullivan O. Impact of service organisation on teaching and training. In: Goethals K, editor. Forensic psychiatry and psychology in Europe. Springer International Publishing AG, part of Springer Nature (2018). doi: 10.1007/978-3-319-74664-7_14

CrossRef Full Text | Google Scholar

3. Wobrock T, Weinmann S, Falkai P, Gaebel W. Quality assurance in psychiatry: quality indicators and guideline implementation. Eur Arch Psychiat Clin Neurosci (2009) 259(Suppl 2):S219–26. doi: 10.1007/s00406-009-0072-7

CrossRef Full Text | Google Scholar

4. Worrall A. The service context for clinical guidelines: supporting guideline implementation by assuring and improving the quality of service in which clinicians work. Int Rev Psychiatry. (2011) 23:336–41. doi: 10.3109/09540261.2011.606542

PubMed Abstract | CrossRef Full Text | Google Scholar

5. Palmer L, Gill P, Dupin M. The Psychiatric Liaison Accreditation Network—an innovative project to improve quality in UK liaison psychiatry services. J Psychosom Rese (2010) 69:619–21. doi: 10.1016/j.jpsychores.2010.10.001

CrossRef Full Text | Google Scholar

6. Expertisecentrum Forensische Psychiatrie (EFP) Quality Networks. https://efp.nl/en/projects/quality-network.

Google Scholar

7. Everitt B, Wessely S. Special problems of trials in psychiatry. In: Everitt B, Wessely S, editors. Clinical trials in psychiatry. Chichester: John Wiley and Sons (2008). p. 71–88. doi: 10.1002/9780470723852

CrossRef Full Text | Google Scholar

8. Kautzky A, Lanzenberger R, Kasper S. Big data guided interventions: predicting treatment response. In: Passos IC, Mwangi B, Kapczinski F, editors. Personalized psychiatry: big data analytics in mental health. Springer Nature Switzerland AG (2019). doi: 10.1007/978-3-030-03553-2_4

CrossRef Full Text | Google Scholar

9. Aimola L, Jasim S, Tripathi N, Tucker S, Worrall A, Quirk A, et al. Impact of peer-led quality improvement networks on quality of inpatient mental health care: study protocol for a cluster randomized controlled trial. BMC Psychiatry (2016) 16:331. doi: 10.1186/s12888-016-1040-1

PubMed Abstract | CrossRef Full Text | Google Scholar

10. Sharma A, Dunn W, O’Toole C, Kennedy HG. The virtual institution: cross-sectional length of stay in general adult and forensic psychiatry beds. Int J Ment Health Syst (2015) 9:25. doi: 10.1186/s13033-015-0017-7

PubMed Abstract | CrossRef Full Text | Google Scholar

11. Erb M, Hodgins S, Freese R, Müller-Isberner R, Jöckel D. Homicide and schizophrenia: maybe treatment does have a preventive effect. Crim Behav Ment Health (2001) 11(1):6–26. doi: 10.1002/cbm.366

PubMed Abstract | CrossRef Full Text | Google Scholar

12. Hodgins S. Research priorities in forensic mental health. Int J Forens MentHealth (2002) 1:7–23. doi: 10.1080/14999013.2002.10471157

CrossRef Full Text | Google Scholar

13. Hodgins S. Violent behaviour among people with schizophrenia: a framework for investigations of causes, and effective treatment, and prevention. Phil Trans R Soc B (2008) 363:2505–18. doi: 10.1098/rstb.2008.0034

PubMed Abstract | CrossRef Full Text | Google Scholar

14. Howner K, Andiné P, Bertilsson G, Hultcrantz M, Lindström E, Mowafi F, et al.. Mapping systematic reviews on forensic psychiatric care: a systematic review identifying knowledge gaps. Front Psychiatry (2018) 9:452. doi: 10.3389/fpsyt.2018.00452

PubMed Abstract | CrossRef Full Text | Google Scholar

15. Giacchetti S, Hamy AS, Delaloge S, Brain E, Berger F, Sigal-Zafrani B, et al. Long-term outcome of the REMAGUS 02 trial, a multicenter randomised phase II trial in locally advanced breast cancer patients treated with neoadjuvant chemotherapy with or without celecoxib or trastuzumab according to HER2 status. Eur J Cancer (2017) 75:323–32. doi: 10.1016/j.ejca.2017.01.008

PubMed Abstract | CrossRef Full Text | Google Scholar

16. European Organisation for Research and Treatment of Cancer: Mission statement (2018). http://www.eortc.org/our-mission/ Accessed. (12 October 2018)

Google Scholar

17. Breast International Group BIG: Mission statement (2018). https://www.bigagainstbreastcancer.org/our-story/our-mission Accessed (12 October 2018).

Google Scholar

18. National Cancer Institute. NCI’s National Clinical Trials Network (2018). https://www.cancer.gov/research/areas/clinical-trials/nctn. Accessed (12 October 2018).

Google Scholar

19. Cancer Core Europe: Who we are; brief (2018). https://www.cancercoreeurope.eu/who-we-are/ Accessed (12 October 2018).

Google Scholar

20. Ostinelli EG, Brooke-Powney MJ, Li X, Adams CE. Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation). Cochr Database Syst Rev (2017) 7:CD009377. doi: 10.1002/14651858.CD009377.pub3

CrossRef Full Text | Google Scholar

21. Macritchie K, Geddes JR, Scott J, Haslam D, de Lima M, Goodwin G. Valproate for acute mood episodes in bipolar disorder. (PMID:12535506). Cochr Database Syst Rev (2003) 2003(1):CD004052. doi: 10.1002/14651858.CD004052

CrossRef Full Text | Google Scholar

22. Everitt B, Wessely S. RCTs in psychiatry: threats, challenges and the future. In: Everitt B, Wessely S, editors. Clinical trials in psychiatry., John Wiley & Sons Chichester (2008). p. 163–80.

Google Scholar

23. Giacco D, Conneely M, Masoud T, Burn E, Priebe S. Interventions for involuntary psychiatric inpatients: a systematic review. Eur Psychiatry (2018) 54:41–50. doi: 10.1016/j.eurpsy.2018.07.005

PubMed Abstract | CrossRef Full Text | Google Scholar

24. Dieterich M, Irving CB, Bergman H, Khokhar MA, Park B, Marshall M. Intensive case management for severe mental illness. Cochr Database Syst Rev (2017) 1:CD007906. doi: 10.1002/14651858.CD007906.pub3

CrossRef Full Text | Google Scholar

25. Kisely SR, Campbell LA, O’Reilly R. Compulsory community and involuntary outpatient treatment for people with severe mental disorders. Cochr Database Syst Rev (2017) 3:CD004408. doi: 10.1002/14651858.CD004408.pub5

CrossRef Full Text | Google Scholar

26. Allen D, Gillen E, Rixson L. The effectiveness of integrated care pathways for adults and children in health care settings: a systematic review. JBI Libr Syst Rev. (2009) (3), 80–129. doi: 10.11124/jbisrir-2009-182

PubMed Abstract | CrossRef Full Text | Google Scholar

27. Cullen AE, Clarke AY, Kuipers E, Hodgins S, Dean K, Fahy TA. A multisite randomized trial of a cognitive skills program for male mentally disordered offenders: violence and antisocial behaviour outcomes. J Consult Clin Psychol (2012) 80:1114–20. doi: 10.1037/a0030291

PubMed Abstract | CrossRef Full Text | Google Scholar

28. Rees-Jones A, Gudjonsson G, Young S. A multi-site-controlled trial of a cognitive skills program for mentally disordered offenders. BMC Psychiatry (2012) 12:44. doi: 10.1186/1471-244X-12-44

PubMed Abstract | CrossRef Full Text | Google Scholar

29. Taylor R, Cella M, Csipke E, Heriot-Maitland C, Gibbs C, Wykes T. Tackling social cognition in schizophrenia: a randomized feasibility trial. Behav Cogn Psychother (2015) 9:1–12. doi: 10.1017/S1352465815000284

CrossRef Full Text | Google Scholar

30. Ahmed AO, Hunter KM, Goodrum NM, Batten NJ, Birgenheir D, Hardison E, et al. A randomized study of cognitive remediation for forensic and mental health patients with schizophrenia. J Psychiatr Res (2015) 68:8–18. doi: 10.1016/j.jpsychires.2015.05.013

PubMed Abstract | CrossRef Full Text | Google Scholar

31. O'Reilly K, Donohoe G, O'Sullivan D, Coyle C, Corvin A, O’Flynn P, et al. A randomized controlled trial of cognitive remediation for a national cohort of forensic patients with schizophrenia or schizoaffective disorder. BMC Psychiatry (2019) 19(1):27. doi: 10.1186/s12888-019-2018-6

PubMed Abstract | CrossRef Full Text | Google Scholar

32. Cure SJ, Adams CE. Forensic trials inform the present and future (letter). Br J Psychiatry (2000) 177:182. doi: 10.1192/bjp.177.2.182-a

CrossRef Full Text | Google Scholar

33. Lindqvist P, Skipworth J. Evidence based rehabilitation in forensic psychiatry. Br J Psychiatry (2000) 176:320–3. doi: 10.1192/bjp.176.4.320

PubMed Abstract | CrossRef Full Text | Google Scholar

34. Lindqvist P, Skipworth J. Finding the evidence in forensic rehabilitation. Br J Psychiatry (2000) 177:372. doi: 10.1192/bjp.177.4.372

CrossRef Full Text | Google Scholar

35. Patel VL, Kaufman DR, Magder SA. The acquisition of medical expertise in complex dynamic environments. In: Ericsson KA, editor. The road to excellence: the acquisition of expert performance in the arts and sciences, sports, and games. Lawrence Erlbaum Associates (1996). p. 127–87.

Google Scholar

36. Collins H, Evans R. Rethinking expertise. London: University of Chicago Press (2007). doi: 10.7208/chicago/9780226113623.001.0001

CrossRef Full Text | Google Scholar

37. Ferrari M. The pursuit of excellence through education. London: Taylor & Francis (2002). doi: 10.4324/9781410604088

CrossRef Full Text | Google Scholar

38. Agency for Clinical Innovation. Understanding the process to develop a Model of Care: an ACI framework. Version 1.0. New South Wales Australia: ACI (2013). [online] https://www.aci.health.nsw.gov.au/:data/assets/pdf_file/0009/181935/HS13-034_Framework-DevelopMoC_D7.pdf. Accessed (12 October 2018).

Google Scholar

39. Bertalanffy L von. General system theory: foundations, development, applications. New York: George Braziller; Revised edition (5 Aug. 2015). ISBN-13: 978-0807600153.

Google Scholar

40. Engel GL. The need for a new medical model: a challenge for biomedicine. Science (1977) 196:129–36. doi: 10.1126/science.847460

PubMed Abstract | CrossRef Full Text | Google Scholar

41. Engel GL. The clinical application of the biopychosocial model. Am J Psychiatry (1980) 137:535–44. doi: 10.1176/ajp.137.5.535

PubMed Abstract | CrossRef Full Text | Google Scholar

42. McLaren N. A critical review of the bio-psycho-social model. Aust N Z J Psychiatry (1998) 32:86–92. doi: 10.3109/00048679809062712

PubMed Abstract | CrossRef Full Text | Google Scholar

43. Burkett GL. Culture, illness, and the biopsychosocial model. Fam Med (1990) 23:287–91.

Google Scholar

44. Thornicroft G, Cooper S, van Bortel T. Capacity building in global mental health research. Harv Rev Psychiatry (2012) 20:13–24. doi: 10.3109/10673229.2012.649117

PubMed Abstract | CrossRef Full Text | Google Scholar

45. Babalola E, Noel P, White R. The biopsychosocial approach and global mental health: synergies and opportunities. Indian J Soc Psychiatry (2017) 33:291–6. doi: 10.4103/ijsp.ijsp_13_17

CrossRef Full Text | Google Scholar

46. Health Improvement Scotland. Integrated care pathways toolkit; child and adolescent pathways, adult and older adult pathways. https://www.icptoolkit.org/home.aspx. Accessed (27th December 2018).

Google Scholar

47. Forrester A, Till A, Simpson A, Shaw J. Mental illness and the provision of mental health services in prisons. Br Med Bull (2018) 127(1):101–9. doi: 10.1093/bmb/ldy027

PubMed Abstract | CrossRef Full Text | Google Scholar

48. Gavin N, Parsons S, Grubin D. Reception screening and mental health needs assessment in a male remand prison. Psychiatr Bull (2003) 27:251. doi: 10.1017/S095560360000252X

CrossRef Full Text | Google Scholar

49. McInerney C, Davoren M, Flynn G, Mullins D, Fitzpatrick M, Caddow M, et al. Implementing a court diversion and liaison scheme in a remand prison by systematic screening of new receptions: a 6 year participatory action research study of 20,084 consecutive male remands. Int J Ment Health Syst (2013) doi: 10.1186/1752-4458-7-18

CrossRef Full Text | Google Scholar

50. O'Neill C, Smith D, Caddow M, Duffy F, Hickey P, Fitzpatrick M, et al. STRESS-testing clinical activity and outcomes for a combined prison in-reach and court liaison service: a 3-year observational study of 6177 consecutive male remands. Int J Ment Health Syst (2016) 10:67. doi: 10.1186/s13033-016-0097-z

PubMed Abstract | CrossRef Full Text | Google Scholar

51. Pillai K, Rouse P, McKenna B, Skipworth J, Cavney J, Tapsell R, et al. From positive screen to engagement in treatment: a preliminary study of the impact of a new model of care for prisoners with serious mental illness. BMC Psychiatry (2016) 16:9. doi: 10.1186/s12888-016-0711-2

PubMed Abstract | CrossRef Full Text | Google Scholar

52. Martin MS, Crocker AG, Potter BK, Wells GA, Grace RM, Colman I. Mental health screening and differences in access to care among prisoners. Can J Psychiatry (2018) doi: 10.1177/0706743718762099

CrossRef Full Text | Google Scholar

53. Flynn D, Smith D, Quirke L, Monks S, Kennedy HG. Ultra high risk of psychosis on committal to a young offender prison: an unrecognised opportunity for early intervention. BMC Psychiatry (2012) 12:100. doi: 10.1186/1471-244X-12-100

PubMed Abstract | CrossRef Full Text | Google Scholar

54. Giblin Y, Kelly A, Kelly E, Kennedy HG, Mohan DJ. Reducing the use of seclusion for mental disorder in a prison: implementing a high support unit in a prison using participant action research. Int J Ment Health Syst (2012) 6:2. doi: 10.1186/1752-4458-6-2

PubMed Abstract | CrossRef Full Text | Google Scholar

55. McKenna B, Skipworth J, Tapsell R, Pillai K, Madell D, Simpson A, et al. Impact of an assertive community treatment model of care on the treatment of prisoners with a serious mental illness. Australas Psychiatry (2018) 26(3):285–9. doi: 10.1177/1039856217748247

PubMed Abstract | CrossRef Full Text | Google Scholar

56. QS world university rankings by subject 2019: Medicine. Accessed (2nd March 2019). https://www.topuniversities.com/university-rankings/university-subject-rankings/2019/medicine.

Google Scholar

57. Academic ranking of world universities (2018). Acccessed (2nd March 2019). http://www.shanghairanking.com/ARWU2018.html.

Google Scholar

60. Hirsch JE. An index to quantify an individual's scientific research output. PNAS (2005) 102(46):16569–72. doi: 10.1073/pnas.0507655102

PubMed Abstract | CrossRef Full Text | Google Scholar

61. Panel on Return on Investment in Health Research. Making an impact: a preferred framework and indicators to measure returns on investment in health research. Can Acad Health Sci (2009).

Google Scholar

62. International Development Research Centre. Towards research excellence for development: the research quality plus assessment instrument. Ottawa, Canada (2014). Available at idrc.ca/EN/Documents/Research-Quality-Plus-Assessment-Instrument.pdf.

Google Scholar

63. Ofir Z, Schwandt T, Duggan C, McLean R. Research Quality Plus (RQ+). In: A holistic approach to evaluating research. Ottawa, Canada: International Development Research Centre (IDRC) (2016).

Google Scholar

64. International Association of Forensic Mental Health Services. About the IAFMHS. http://www.iafmhs.org/About. Accessed (28th Feb 2019).

Google Scholar

65. Brown CSH, Lloyd K. OPRISK: a structured checklist assessing security needs for mentally disordered offenders referred to high security hospital. Crim Behav Ment Health (2008) 18:190–202. doi: 10.1002/cbm.689

PubMed Abstract | CrossRef Full Text | Google Scholar

66. Flynn G, Neill C, McInerney C, Kennedy HG. The DUNDRUM-1 structured professional judgment for triage to appropriate levels of therapeutic security: retrospective-cohort validation study. BMC Psychiatry (2011) 11:43. doi: 10.1186/1471-244X-11-43

PubMed Abstract | CrossRef Full Text | Google Scholar

67. Flynn G, Neill C, Kennedy HG. DUNDRUM-2: prospective validation of a structured professional judgment instrument assessing priority for admission from the waiting list for a Forensic Mental Health Hospital. BMC Res Notes (2011) 4:230. doi: 10.1186/1756-0500-4-230

PubMed Abstract | CrossRef Full Text | Google Scholar

68. Freestone M, Bull D, Brown R, Boast N, Blazey F, Gilluley P. Triage, decision-making and follow-up of patients referred to a UK forensic service: validation of the DUNDRUM toolkit. BMC Psychiatry (2015) (15), 239. doi: 10.1186/s12888-015-0620-9

PubMed Abstract | CrossRef Full Text | Google Scholar

69. Daniels N, Sabin JE. Setting limits fairly: can we learn to share medical resources?. Oxford: Oxford University Press (2002). doi: 10.1093/acprof:oso/9780195149364.001.0001

CrossRef Full Text | Google Scholar

70. Davoren M, O'Dwyer S, Abidin Z, Naughton L, Gibbons O, Doyle E, et al. Prospective in-patient cohort study of moves between levels of therapeutic security: the DUNDRUM-1 triage security, DUNDRUM-3 programme completion and DUNDRUM-4 recovery scales and the HCR-20. BMC Psychiatry (2012) 12:80. doi: 10.1186/1471-244X-12-80

PubMed Abstract | CrossRef Full Text | Google Scholar

71. Eckert M, Schel S, Kennedy H, Bulten E. Patient characteristics related to length of stay in Dutch forensic psychiatric care. J Forens Psychiatry Psychol (2017) 28(6):863–80. doi: 10.1080/14789949.2017.1332771

CrossRef Full Text | Google Scholar

72. Adams J, Thomas SDM, Mackinnon T, Eggleton D. The risks, needs and stages of recovery of a complete forensic patient cohort in an Australian state. BMC Psychiatry (2018) 18(1):35. doi: 10.1186/s12888-017-1584-8

PubMed Abstract | CrossRef Full Text | Google Scholar

73. Adams J, Thomas S, Mackinnon T, Eggleton D. How secure are the secure psychiatric units in New South Wales? Australas Psychiatry (2019) 27(1):32–5. doi: 10.1177/1039856218804334

PubMed Abstract | CrossRef Full Text | Google Scholar

74. Simpson AI, Penney SR, Fernane S, Wilkie T. The impact of structured decision making on absconding by forensic psychiatric patients: results from an AB design study. BMC Psychiatry (2015) 15(1):103. doi: 10.1186/s12888-015-0474-1

PubMed Abstract | CrossRef Full Text | Google Scholar

75. Wilkie T, Penney SR, Fernane S, Simpson AI. Characteristics and motivations of absconders from forensic mental health services: a case control study. BMC Psychiatry (2014) 14:91. doi: 10.1186/1471-244X-14-91

PubMed Abstract | CrossRef Full Text | Google Scholar

76. Wilson CM, Nicholls TL, Charette Y, Seto MC, Crocker AG. Factors associated with review board dispositions following re-hospitalization among discharged persons found not criminally responsible. Behav Sci Law (2016) 34:278–94. doi: 10.1002/bsl.2220

PubMed Abstract | CrossRef Full Text | Google Scholar

77. Davoren M, Abidin Z, Naughton L, Gibbons O, Nulty A, Wright B. Kennedy HG. Prospective study of factors influencing conditional discharge from a forensic hospital: the DUNDRUM-3 programme completion and DUNDRUM-4 recovery structured professional judgement instruments and risk. BMC Psychiatry (2013) 13:185. doi: 10.1186/1471-244X-13-185

PubMed Abstract | CrossRef Full Text | Google Scholar

78. Davoren M, Hennessy S, Conway C, Marrinan S, Gill P, Kennedy HG. Recovery and concordance in a secure forensic psychiatry hospital —the self rated DUNDRUM-3 programme completion and DUNDRUM-4 recovery scales. BMC Psychiatry (2015) 15:61. doi: 10.1186/s12888-015-0433-x

PubMed Abstract | CrossRef Full Text | Google Scholar

79. McGorry P, Keshavan M, Goldstone S, Amminger P, Allott K, et al. Biomarkers and clinical staging in psychiatry. World Psychiatry (2014) 13:211–23. doi: 10.1002/wps.20144

PubMed Abstract | CrossRef Full Text | Google Scholar

80. McGorry PD, Hartmann JA, Spooner R, Nelson B. Beyond the “at risk mental state” concept: transitioning to transdiagnostic psychiatry. World Psychiatry (2018) 17(2):133–42. doi: 10.1002/wps.20514

PubMed Abstract | CrossRef Full Text | Google Scholar

81. Salagre E, Dodd S, Aedo A, Rosa A, Amoretti S, Pinzon J, et al. Toward precision psychiatry in bipolar disorder: staging 2.0. Front Psychiatry (20182018) 9:641. doi: 10.3389/fpsyt.2018.00641

PubMed Abstract | CrossRef Full Text | Google Scholar

82. Lavoie S, Polari AR, Goldstone S, Nelson B, McGorry PD. Staging model in psychiatry: review of the evolution of electroencephalography abnormalities in major psychiatric disorders. Early Interv Psychiatry (2019) doi: 10.1111/eip.12792

CrossRef Full Text | Google Scholar

83. Streb LG, Berk M, Kapczinski F. A short introductory note about neuroprogression in psychiatry. In: Kapczinski F, da Silva Magalhaes PV, Berk M, editors. Neuroprogression in psychiatry. Oxford: Oxford University Press (2019). ISBN 978-0-19-878714-3. doi: 10.1093/med/9780198787143.001.0001

CrossRef Full Text | Google Scholar

84. Translational psychiatry: aims and scope of journal. Accessed on (2nd March 2019). https://www.nature.com/tp/about.

Google Scholar

85. Crocker AG, Livingstone JD, Leclair MC. Forensic mental health systems internationally. In: Roesch R, Cook AN, editors. Handbook of forensic mental health systems. Taylor & Francis (2017). doi: 10.4324/9781315627823-2

CrossRef Full Text | Google Scholar

86. Richter MS, O’Reilly K, O’Sullivan D, O’Flynn P, Corvin A, Donohoe G, et al. Prospective observational cohort study of 'treatment as usual' over four years for patients with schizophrenia in a national forensic hospital. BMC Psychiatry (2018) 18:289. doi: 10.1186/s12888-018-1862-0

PubMed Abstract | CrossRef Full Text | Google Scholar

87. Bzdok D, Schulz M, Lindquist M. Emerging shifts in neuroimaging data analysis in the era of “big data”. In: Passos IC, Mwangi B, Kapczinski F, editors. Personalized psychiatry: big data analytics in mental health. Springer Nature Switzerland AG (2019). doi: 10.1007/978-3-030-03553-2_6

CrossRef Full Text | Google Scholar

88. Tognin S, van Hell HH, Merritt K, Winter-van Rossum I, Bossong MG, Kempton MJ, et al. Towards precision medicine in psychosis: benefits and challenges of multimodal multicenter studies—PSYSCAN: translating neuroimaging findings from research into clinical practice. Schizophr Bull (2019), pii: sbz067. doi: 10.1093/schbul/sbz067

CrossRef Full Text | Google Scholar

89. Shinkfield G, Ogloff J. A review and analysis of routine outcome measures for forensic mental health services. Int J Forens MentHealth (2014) 13:252–71. doi: 10.1080/14999013.2014.939788

CrossRef Full Text | Google Scholar

90. Porter M, Larsson S, Lee TH. Standardizing patient outcomes measurement. N Engl J Med (2016) 374:504–6. doi: 10.1056/NEJMp1511701

PubMed Abstract | CrossRef Full Text | Google Scholar

91. Kretschmer E. Korperbau und Charakter. Berlin: Verlag von Julius Springer (1922).

Google Scholar

92. Jaspers K. Allgemeine Psychopathologie 1913; General psychopathology volumes 1 & 2. Translated by J Hoenig and MW Hamilton. Baltimore and London. The Johns Hopkins Press. 1997; Springer Verlag Berlin Heidelberg 1959, Manchester University Press 1963.

Google Scholar

93. Muller-Isberner M, Webster CD, Gretenkord L. Measuring progress in hospital order treatment: relationship between levels of security and C and R scores of the HCR-20. Int J Forensic Men Health (2007) 6:113–21. doi: 10.1080/14999013.2007.10471256

CrossRef Full Text | Google Scholar

94. Pillay SM, Oliver B, Butler L, Kennedy HG. Risk stratification and the care pathway. Irish J Psychol Medi (2008) 25(4):123–7. doi: 10.1017/S0790966700011228

CrossRef Full Text | Google Scholar

95. Abidin Z, Davoren M, Naughton L, Gibbons O, Nulty A, Kennedy HG. Susceptibility (risk and protective) factors for in-patient violence and self-harm: prospective study of structured professional judgement instruments START and SAPROF, DUNDRUM-3 and DUNDRUM-4 in forensic mental health services. BMC Psychiatry (2013) 13:197. doi: 10.1186/1471-244X-13-197

PubMed Abstract | CrossRef Full Text | Google Scholar

96. Chang Z, Lichtenstein P, Långström N, Larsson H, Fazel S. Association between prescription of major psychotropic medications and violent reoffending after prison release. JAMA (2016) 316(17):1798–807. doi: 10.1001/jama.2016.15380

PubMed Abstract | CrossRef Full Text | Google Scholar

97. Wolf A, Whiting D, Fazel S. Violence prevention in psychiatry: an umbrella review of interventions in general and forensic psychiatry. J Forens Psychiatry Psychol. (2017) 28(5):659–73. doi: 10.1080/14789949.2017.1284886

PubMed Abstract | CrossRef Full Text | Google Scholar

98. Fazel S, Hayes AJ, Bartellas K, Clerici M, Trestman R. Mental health of prisoners: prevalence, adverse outcomes, and interventions. Lancet Psychiatry. (2016) 3(9):871–81. doi: 10.1016/S2215-0366(16)30142-0

PubMed Abstract | CrossRef Full Text | Google Scholar

99. Fazel S, Wolf A, Fimińska Z, Larsson H. Mortality, rehospitalisation and violent crime in forensic psychiatric patients discharged from hospital: rates and risk factors. PLoS One (2016) 11(5):e0155906. doi: 10.1371/journal.pone.0155906

PubMed Abstract | CrossRef Full Text | Google Scholar

100. Rosa AR, Lima F. Functioning and illness progression in severe mental illness. In: Kapczinski F, da Silva Maghalhaes PV, editors. Neuroprogression in psychiatry. Oxford University Press (2019). ISBN 978-0-19-878714-3.

Google Scholar

101. Torous J, Bamiri N, Keshavan M. A clinical perspective on big data in mental health. In: Passos IC, Mwangi B, Kapczinski F, editors. Personalized psychiatry: big data analytics in mental health. Springer Nature Health AG (2019). doi: 10.1007/978-3-030-03553-2_3

CrossRef Full Text | Google Scholar

102. Silva RF, Plis SM. How to integrate data from multiple biological layers in mental health?. In: Passos IC, Mwangi B, Kapczinski F, editors. Personalized psychiatry: big data analytics in mental health. Springer Nature Health AG (2019). doi: 10.1007/978-3-030-03553-2_8

CrossRef Full Text | Google Scholar

103. Appleby L, Kapur N, Shaw J, Hunt IM, Ibrahim S, Gianatsi M, et al. The National Confidential Inquiry into Suicide and Safety in Mental Health. Annual report: England, Northern Ireland, Scotland, Wales. October 2018.University of Manchester. http://documents.manchester.ac.uk/display.aspx?DocID=38469.

Google Scholar

104. Burleyson GT, Tielsch JM, Cameron JL. The effects of regionalization on cost and outcome for one general high-risk surgical procedure. Ann Surg (1995) 221(1):43–9. doi: 10.1097/00000658-199501000-00005

PubMed Abstract | CrossRef Full Text | Google Scholar

105. Tseng JF, Pisters PWT, Lee JE, Wang H, Gomez HF, Sun CC, et al. The learning curve in pancreatic surgery. Surgery (2007) 141(4):456–63. doi: 10.1016/j.surg.2006.09.013

PubMed Abstract | CrossRef Full Text | Google Scholar

106. Max Schmidt CM, Turrini O, Parikh P, House MG, Zyromski NJ, Nakeeb A, et al. Effect of hospital volume, surgeon experience, and surgeon volume on patient outcomes after pancreaticoduodenectomy: a single-institution experience. Arch Surg (2010) 145(7):634–40. doi: 10.1001/archsurg.2010.118

PubMed Abstract | CrossRef Full Text | Google Scholar

107. Amato L, Colais P, Davoli M, Ferroni E, Fusco D, Minozzi S, et al. Volume and health outcomes: evidence from systematic reviews and from evaluation of Italian hospital data. Epidemiol Prev (2013) 37(2–3 Suppl 2):1–100.

Google Scholar

108. Amato L, Fusco D, Acampora A, Bontempi K, Rosa AC, Colais P, et al. Volume and health outcomes: evidence from systematic reviews and from evaluation of Italian hospital data. Epidemiol Prev (2017) 41(5–6 (Suppl 2)):1–128. doi: 10.19191/EP17.5-6S2.P001.100

CrossRef Full Text | Google Scholar

109. Lee B, Kim K, Park Y, Lim MC, Bristow RE. Impact of hospital care volume on clinical outcomes of laparoscopic radical hysterectomy for cervical cancer: a systematic review and meta-analysis. Medicine (Baltimore). (2018) 97(49):e13445. doi: 10.1097/MD.0000000000013445

PubMed Abstract | CrossRef Full Text | Google Scholar

110. Ananth CV, Lavery JA, Friedman AM, Wapner RJ, Wright JD. Serious maternal complications in relation to severe pre-eclampsia: a retrospective cohort study of the impact of hospital volume. BJOG (2017) 124(8):1246–53. doi: 10.1111/1471-0528.14384

PubMed Abstract | CrossRef Full Text | Google Scholar

111. Hata T, Motoi F, Ishida M, Naitoh T, Katayose Y, Egawa S, et al. Effect of hospital volume on surgical outcomes after pancreaticoduodenectomy: a systematic review and meta-analysis. Ann Surg. (2016) 263(4):664–72. doi: 10.1097/SLA.0000000000001437

PubMed Abstract | CrossRef Full Text | Google Scholar

112. Hehir MP, Ananth CV, Wright JD, Siddiq Z, D’Alton ME, Friedman AM. Severe maternal morbidity and comorbid risk in hospitals performing <1000 deliveries per year. Am J Obstet Gynecol (2017) 216(2):179.e1–179.e12. doi: 10.1016/j.ajog.2016.10.029

CrossRef Full Text | Google Scholar

113. Friedman AM, Ananth CV, Huang Y, D'Alton ME, Wright JD. Hospital delivery volume, severe obstetrical morbidity, and failure to rescue. Am J Obstet Gynecol (2016) 215(6):795.e1–795.e14. doi: 10.1016/j.ajog.2016.07.039

CrossRef Full Text | Google Scholar

114. Brown BB, Patel C, McInnes E, Mays N, Young J, Haines M. The effectiveness of clinical networks in improving quality of care and patient outcomes: a systematic review of quantitative and qualitative studies. BMC Health Serv Res (2016) 16:360. doi: 10.1186/s12913-016-1615-z

PubMed Abstract | CrossRef Full Text | Google Scholar

115. EU Joint Programme - –Neurodegenerative Disease Research (JPND). Research strategy tackling the challenge of Alzheimer’s and other neurodegenerative diseases in Europe. JPND Research Strategy: published 2012 UK Medical Research Council ISSN 2049-3290.

Google Scholar

116. Webster CD, Douglas KS, Eaves D, Hart SD. HCR–20: assessing risk for violence. Burnaby: Mental Health Law and Policy Institute, Simon Fraser University (1997).

Google Scholar

117. Grisso T, Applebeum PS, Hill-Fotouchi C. The MacCAT-T: a clinical tool to assess patients’ capacities to make treatment decisions. Psychiatr Serv (1997) 48:1415–9. doi: 10.1176/ps.48.11.1415

PubMed Abstract | CrossRef Full Text | Google Scholar

118. Kennedy HG, O’Neill C, Flynn G, Gill P, Davoren M. The DUNDRUM toolkit V1.0.30, 1.0.30, Dublin. TARA (2016), 1–141.

Google Scholar

119. Kennedy HG, O’Reilly K, Davoren M, O’Flynn P, O’Sullivan OP. Chapter: how to measure progress in forensic care. In: Völlm B, editor. Long-term forensic-psychiatric care: clinical, ethical and legal challenges. Series International Library of Ethics, Law and the New Medicine. Heidelberg: Springer Verlag.

Google Scholar

120. McGuire J. A review of effective interventions for reducing aggression and violence. Phil Trans R Soc B (2008) 363:2577–97. doi: 10.1098/rstb.2008.0035

PubMed Abstract | CrossRef Full Text | Google Scholar

121. Wampold BE. How important are the common factors in psychotherapy? An update. World Psychiatry (2015) 14:270–7. doi: 10.1002/wps.20238

PubMed Abstract | CrossRef Full Text | Google Scholar

122. Murphy MJ, Newby JM, Butow P, Kirsten L, Allison K, Loughnan S, et al. iCanADAPT Early protocol: randomised controlled trial (RCT) of clinician supervised transdiagnostic internet-delivered cognitive behaviour therapy (iCBT) for depression and/or anxiety in early stage cancer survivors -vs- treatment as usual. BMC Cancer (2017) 17(1):193. doi: 10.1186/s12885-017-3182-z

PubMed Abstract | CrossRef Full Text | Google Scholar

123. Paxton R, Shrubb S, Griffiths H, Cameron L, Maunder L. Tiered approach: matching mental health services to needs. J Ment Health (2000) 9:137–44. doi: 10.1080/09638230050009131

CrossRef Full Text | Google Scholar

124. Kessler RC, Bernecker SL, Bossarte RM, Luedtke AR, McCarthy JF, Nock MK, et al. The role of big data analytics in predicting suicide. In: Passos IC, Mwangi B, Kapczinski F, editors. Personalized psychiatry: big data analytics in mental health. Springer Nature Health AG (2019). doi: 10.1007/978-3-030-03553-2_5

CrossRef Full Text | Google Scholar

125. The Forensic Mental Health Services Managed Care Network (Forensic Network). https://www.forensicnetwork.scot.nhs.uk/forensic-network/.

Google Scholar

126. Expertisecentrum Forensische Psychiatrie (EFP). https://efp.nl/en.

Google Scholar

127. Draper B, Brodaty H, Low LF. A tiered model of psychogeriatric service delivery: an evidence-based approach. Int J Geriatr Psychiatry (2006) 21(7):645–53. doi: 10.1002/gps.1541

PubMed Abstract | CrossRef Full Text | Google Scholar

128. Hutchison SD, Steginga SK, Dunn J. The tiered model of psychosocial intervention in cancer: a community based approach. Psychooncology (2006) 15(6):541–6. doi: 10.1002/pon.973

PubMed Abstract | CrossRef Full Text | Google Scholar

129. NHS Education for Scotland. The Matrix 2014: a guide to delivering evidence-based psychological therapies in Scotland. Part 1: delivering evidence-based psychological therapies. The Scottish Government. https://www.nes.scot.nhs.uk/media/3325612/matrix_part_1.pdf.

Google Scholar

130. NHS Education for Scotland. The Matrix 2014: a guide to delivering evidence-based psychological therapies in Scotland. Part 2: the evidence tables and how to use them. The Scottish Government. https://www.nes.scot.nhs.uk/media/3325318/matrix_-_part_2.pdf.

Google Scholar

131. NHS Education for Scotland. The Matrix 2014: The Matrix evidence services: forensic services. The Scottish Government. https://www.nes.scot.nhs.uk/media/3325324/matrix_-_forensicservicestables.pdf.

Google Scholar

132. Green MF, Nuechterlein KH, Kern RS, Baade LE, Fenton WS, Gold JM, et al. Functional co-primary measures for clinical trials in schizophrenia: results from the MATRICS Psychometric and Standardization Study. Am J Psychiatry (2008) 165(2):221–8. doi: 10.1176/appi.ajp.2007.07010089

PubMed Abstract | CrossRef Full Text | Google Scholar

133. Aimola L, Jasim S, Tripathi N, Bassett P, Quirk A, Worrall A, et al. Impact of a peer-review network on the quality of inpatient low secure mental health services: cluster randomised control trial. BMC Health Serv Res (2018) 18:994. doi: 10.1186/s12913-018-3797-z

PubMed Abstract | CrossRef Full Text | Google Scholar

134. Rangan A, Brealey S, Carr A. Orthopaedic trial networks. J Bone Joint Surg Am. (2012) 94 Suppl 1:97–100. doi: 10.2106/JBJS.L.00241

CrossRef Full Text | Google Scholar

135. Tansella M, Thornicroft G. A conceptual framework for mental health services: the matrix model. Psychol Med (1998) 28:503–8. doi: 10.1017/S0033291796005880

PubMed Abstract | CrossRef Full Text | Google Scholar

136. Thornicroft G, Tansella M. The mental health matrix: a manual to improve services. Cambridge: Cambridge University press (1999). doi: 10.1017/CBO9780511549557

CrossRef Full Text | Google Scholar

137. O’Reilly R, Allison S, Bastiampiallai T. Observed outcomes: an approach to calculate the optimum number of psychiatric beds. Adm Policy Ment Health Ment Health Serv Res (2019) 46:507–517 .doi: 10.1007/s10488-018-00917-8

CrossRef Full Text | Google Scholar

Keywords: excellence, quality, forensic - psychiatric practice, hospital, tiered

Citation: Kennedy HG, Simpson A and Haque Q (2019) Perspective On Excellence in Forensic Mental Health Services: What We Can Learn From Oncology and Other Medical Services. Front. Psychiatry 10:733. doi: 10.3389/fpsyt.2019.00733

Received: 14 May 2019; Accepted: 12 September 2019;
Published: 18 October 2019.

Edited by:

Thomas Nilsson,University of Gothenburg, Sweden

Reviewed by:

Anne G. Crocker, Universitéde Montréal, Canada
Sean Kaliski, University of Cape Town, South Africa

Copyright © 2019 Kennedy, Simpson and Haque. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Harry G, Kennedy, kennedh@tcd.ie

†ORCID: Alexander Simpson, orcid.org/0000-0003-0478-2583; Harry G. Kennedy, orcid.org/0000-0003-3174-3272

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