%A He,Xun %A Duan,Xi-Ling %A Liu,Jing-Song %D 2022 %J Frontiers in Psychiatry %C %F %G English %K neuropsychiatric systemic lupus erythematosus,case report,Hair loss,diagnosis,symptom %Q %R 10.3389/fpsyt.2022.839566 %W %L %M %P %7 %8 2022-May-13 %9 Case Report %# %! Systemic lupus erythematosus %* %< %T A Case of Neuropsychiatric Systemic Lupus Erythematosus With Hair Loss as the First Diagnostic Symptom %U https://www.frontiersin.org/articles/10.3389/fpsyt.2022.839566 %V 13 %0 JOURNAL ARTICLE %@ 1664-0640 %X Neuropsychiatric systemic lupus erythematosus is a serious complication of systemic lupus erythematosus. A 33-year-old female patient had repeated hair loss for more than 3 years. A dermatologic examination showed several pieces of irregularly shaped hair loss patterns in the center of the patient's scalp. The systemic treatment included oral hydroxychloroquine, aspirin enteric-coated tablets and prednisone, and intrathecal injection of dexamethasone and methotrexate. The local treatment included intralesional injection of triamcinolone acetonide and lidocaine in the lesion area, 0.1% tacrolimus ointment for external use. After 2-month treatment, hair regrew in a non-scarring patchy alopecia region with no further hair loss.