Frontiers in Aging Neuroscience

Original Research

Published on 06 Jun 2025

Diffusion tensor imaging of sequential neuropathological patterns in progressive supranuclear palsy

in Parkinson’s Disease and Aging-related Movement Disorders

Lavinia A. Bârlescu
Günter U. Höglinger
Heiko Volkmann
Albert C. Ludolph
Kelly Del Tredici
Heiko Braak
the DESCRIBE-PSP Study Group
Hans-Peter Müller
Jan Kassubek
Moritz Brandt

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1569302

3,500 views

Original Research

Published on 06 Jun 2025

Differential effects of concentric and eccentric contractions on the primary motor cortex in healthy young and elderly participants

in Neurocognitive Aging and Behavior

Marion Desachy
Nelly Héraud
Julien Lagarde
Simon Pla
Alain Varray

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1553277

3,419 views

Methods

Published on 06 Jun 2025

Normal and slow learners: a new discriminative method based on the speed of spatial learning in aged mice

in Neurocognitive Aging and Behavior

Céline Duffau
Senka Hadzibegovic
Vojislav Andelkovic
Bruno Bontempi
Olivier Nicole

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1567929

2,599 views

Mini Review

Published on 05 Jun 2025

Research progress on the role of exercise-regulated reactive astrocytes in the prevention and treatment of Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Quan Yang
Chunyu Zhuang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1561006

4,308 views
1 citation

Original Research

Published on 05 Jun 2025

The aging self: how older men and women reflect on themselves and others

in Neurocognitive Aging and Behavior

Marta Paź
Anna Nowicka

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1600029

2,621 views
1 citation

Systematic Review

Published on 05 Jun 2025

Functional brain changes in vascular cognitive impairment: a whole brain ALE meta-analysis

in Neurocognitive Aging and Behavior

Chunyang Zhang
Mingchen Xue
Han Zhang
Juan Li
Mingli He

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1521457

3,815 views
5 citations

Original Research

Published on 04 Jun 2025

Distinct trajectory patterns of neutrophil-to-albumin ratio predict clinical outcomes after endovascular therapy in large vessel occlusion stroke

in Neuroinflammation and Neuropathy

Weiwei Gao
Junxuan Sun
Lingfeng Yu
Jingjing She
Yanan Zhao
Lijuan Cai
Xingyu Chen
Renjing Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1570662

2,775 views
2 citations

Original Research

Published on 04 Jun 2025

Association between sarcopenic obesity and dementia in the Chinese elderly using different definitions of obesity: evidence from the CHARLS

in Alzheimer's Disease and Related Dementias

Lang Peng
Qingwei Xiang
Ge Jia
Renyi Yin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1540272

8,860 views
4 citations

Original Research

Published on 04 Jun 2025

Interventions for cognitive frailty: developing a Delphi consensus with multidisciplinary and multisectoral experts

in Neurocognitive Aging and Behavior

Carol A. Holland
Nikolett Dravecz
Susan Broughton
Lynne A. Barker
Fidelia Bature
Charlotte Clarke
Isaac M. Danat
Sayani Das
Irundika H. K. Dias
Annabel Dawson

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1541048

6,931 views

Original Research

Published on 04 Jun 2025

Non-linear relationship between calf circumference and global cognition in Chinese population: a cross-sectional study of 12,102 Chinese older adults

in Neurocognitive Aging and Behavior

Yuting Nie
Cheng Gu
Ruipeng Wu
Fulin Gao
Le Zhang
Yamin Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1473135

3,170 views
1 citation

Review

Published on 02 Jun 2025

Neurobiological and therapeutic landmarks of depression associated with Alzheimer’s disease dementia

in Alzheimer's Disease and Related Dementias

Ilinca Untu
Michael Davidson
Gabriela-Dumitrita Stanciu
Jonathan Rabinowitz
Romeo-Petru Dobrin
Diana-Sabina Vieru
Bogdan-Ionel Tamba

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1584607

5,156 views
1 citation

Review

Published on 02 Jun 2025

Research progress of deubiquitinating enzymes in cerebral ischemia-reperfusion injury

in Neuroinflammation and Neuropathy

XiaoHong Qin
JiangRui Zhu
HaoRan Lu
MaoRui Yi
ZiLong Zhao
WenFei Zhang
Jing Cheng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1588920

5,626 views
2 citations

Original Research

Published on 30 May 2025

Triglyceride-glucose indices predict all-cause mortality after stroke in NHANES 1999–2018

in Neuroinflammation and Neuropathy

Jiaqian Zheng
Weiwen Mao
Mengqian Sang
Xinyu Pan
Yiluo Xie
Yichi Xie

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1617419

4,389 views
1 citation

Study Protocol

Published on 30 May 2025

Effect of transcranial magnetic stimulation combined with transcutaneous auricular vagus nerve stimulation on mild cognitive impairment: a study protocol for a randomized controlled trial

in Neurocognitive Aging and Behavior

Jingjing Zhang
Jun Ma
Yao Rao
Jiali Wu
Hui Xu
Jiawei Ni
Zhiwei Zhao
Cong Wang
Chunlei Shan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1600921

4,500 views
1 citation

Original Research

Published on 30 May 2025

Healthy aging in rats is associated with a decline in the ability to inhibit maladaptive responses, but not in measures of self-control by delayed gratification

in Neurocognitive Aging and Behavior

Adam T. Brockett
Xavier Sciarillo
Xuan Li
Matthew R. Roesch

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1579934

1,702 views

Systematic Review

Published on 30 May 2025

Bibliometric analysis of global research on PD-L1/PD-1 pathway and neurodegenerative diseases over the last two decades (2004–2023)

in Neurocognitive Aging and Behavior

Jialin Wu
Chaojin Zhang
Qiang Cao
Wei Xuan
Xiaorong Huai
Jie Zhou
Jie Tian

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1570428

2,763 views

Original Research

Published on 30 May 2025

Potential cerebrospinal fluid metabolomic biomarkers and early prediction model for Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Yifan Zhang
Yuexin Yan
Xiangxu Kong
Haijun Zhang
Shengyuan Su

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1582362

2,882 views

Original Research

Published on 30 May 2025

Integrative single-cell and cell-free plasma RNA transcriptomics identifies biomarkers for early non-invasive AD screening

in Alzheimer's Disease and Related Dementias

Li Wu
Renxin Zhang
Yichao Wang
Shaoxing Dai
Naixue Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1571783

3,765 views
1 citation

Original Research

Published on 30 May 2025

Blood essential trace elements and Alzheimer’s disease biomarkers in midlife

in Alzheimer's Disease and Related Dementias

Xin Wang
Kelly M. Bakulski
Carrie A. Karvonen-Gutierrez
Sung Kyun Park
David Morgan
Brian P. Jackson
Roger L. Albin
Henry L. Paulson

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1539749

2,867 views
3 citations

Original Research

Published on 30 May 2025

Risk factors and mediation role of sleep quality for depression in cognitively frail older adults: a cross-sectional study

in Neurocognitive Aging and Behavior

Xiaoxing Lai
Yonghua Cai
Hongwei Zhu
Zhiyuan Zhang
Xinyue Zhang
Yang Li
Jiazhen Liu
Xiaopeng Huo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1541555

2,426 views
2 citations

Original Research

Published on 30 May 2025

Global and tract-specific differences between younger and older adults in DTI measures of white matter integrity

in Neurocognitive Aging and Behavior

Stephanie Matijevic
Lee Ryan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1562660

1,749 views
1 citation

Original Research

Published on 30 May 2025

Association of neutrophil-percentage-to-albumin ratio with mortality in older stroke survivors

in Neuroinflammation and Neuropathy

Jie Huang
Xiaowei Zhang
Luyao Ding
Jiaxiang Yu
Mingshen Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1611289

3,151 views
2 citations

Study Protocol

Published on 27 May 2025

Protocol of a randomized, single-blind, controlled trial of an 18-month, home-based, high-intensity, exercise intervention in older, cognitively unimpaired APOE ε4 carriers

in Neurocognitive Aging and Behavior

Stephen M. Rao
Alexandria L. Chorba
M. J. Helppi
Alina Tuladhar
Amanda L. Penko
Sarah Holley
Brandon Nehls
Sabrina Paulino
Matthew C. Streicher
Audrey Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1584115

3,623 views

Original Research

Published on 27 May 2025

Predictive model for the therapeutic effect of bilateral subthalamic nucleus deep brain stimulation on the freezing of gait in Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Qi Limuge
Yuqing Zhang
Xiaofei Jia
Fang Wang
Dongsheng Yu
Lixia Chen
Li Zhang
Yongqiang Jiang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1511845

2,424 views

7,808 articles

articles

Diffusion tensor imaging of sequential neuropathological patterns in progressive supranuclear palsy

Differential effects of concentric and eccentric contractions on the primary motor cortex in healthy young and elderly participants

Normal and slow learners: a new discriminative method based on the speed of spatial learning in aged mice

Research progress on the role of exercise-regulated reactive astrocytes in the prevention and treatment of Parkinson’s disease

The aging self: how older men and women reflect on themselves and others

Functional brain changes in vascular cognitive impairment: a whole brain ALE meta-analysis

Distinct trajectory patterns of neutrophil-to-albumin ratio predict clinical outcomes after endovascular therapy in large vessel occlusion stroke

Association between sarcopenic obesity and dementia in the Chinese elderly using different definitions of obesity: evidence from the CHARLS

Interventions for cognitive frailty: developing a Delphi consensus with multidisciplinary and multisectoral experts

Non-linear relationship between calf circumference and global cognition in Chinese population: a cross-sectional study of 12,102 Chinese older adults

Neurobiological and therapeutic landmarks of depression associated with Alzheimer’s disease dementia

Research progress of deubiquitinating enzymes in cerebral ischemia-reperfusion injury

Triglyceride-glucose indices predict all-cause mortality after stroke in NHANES 1999–2018

Effect of transcranial magnetic stimulation combined with transcutaneous auricular vagus nerve stimulation on mild cognitive impairment: a study protocol for a randomized controlled trial

Healthy aging in rats is associated with a decline in the ability to inhibit maladaptive responses, but not in measures of self-control by delayed gratification

Bibliometric analysis of global research on PD-L1/PD-1 pathway and neurodegenerative diseases over the last two decades (2004–2023)

Potential cerebrospinal fluid metabolomic biomarkers and early prediction model for Parkinson’s disease

Integrative single-cell and cell-free plasma RNA transcriptomics identifies biomarkers for early non-invasive AD screening

Blood essential trace elements and Alzheimer’s disease biomarkers in midlife

Risk factors and mediation role of sleep quality for depression in cognitively frail older adults: a cross-sectional study

Global and tract-specific differences between younger and older adults in DTI measures of white matter integrity

Association of neutrophil-percentage-to-albumin ratio with mortality in older stroke survivors

Protocol of a randomized, single-blind, controlled trial of an 18-month, home-based, high-intensity, exercise intervention in older, cognitively unimpaired APOE ε4 carriers

Predictive model for the therapeutic effect of bilateral subthalamic nucleus deep brain stimulation on the freezing of gait in Parkinson’s disease