Frontiers in Aging Neuroscience

Original Research

Published on 11 Apr 2025

Baicalein ameliorates cognitive decline induced by chronic cerebral hypoperfusion through the SIRT1-mediated Notch1 pathway to improve angiogenesis and suppress neuroinflammation

in Neurocognitive Aging and Behavior

Meixi Li
Jiaxi Song
Xiaoli Niu
Feng Mo
Xiaohua Xie
Xiuqin Li
Yu Yin
Tianjun Wang
Xiujuan Song
Jingze Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1521353

2,726 views
1 citation

Original Research

Published on 11 Apr 2025

Explainable graph neural network based on metabolic brain imaging for differential diagnosis of parkinsonism

in Neurocognitive Aging and Behavior

Ronghua Ling
Xingxing Cen
Shaoyou Wu
Min Wang
Ying Zhang
Juanjuan Jiang
Jiaying Lu
Yingqian Liu
Chuantao Zuo
Jiehui Jiang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1580910

3,924 views
3 citations

Systematic Review

Published on 10 Apr 2025

Frontotemporal dementia: a systematic review of artificial intelligence approaches in differential diagnosis

in Alzheimer's Disease and Related Dementias

Serena Dattola
Augusto Ielo
Giuseppe Varone
Alberto Cacciola
Angelo Quartarone
Lilla Bonanno

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1547727

7,595 views
5 citations

Correction

Published on 09 Apr 2025

Corrigendum: Boosting antioxidant self-defenses by grafting astrocytes rejuvenates the aged microenvironment and mitigates nigrostriatal toxicity in parkinsonian brain via an Nrf2-driven Wnt/β-catenin prosurvival axis

in Parkinson’s Disease and Aging-related Movement Disorders

Maria Francesca Serapide
Francesca L'Episcopo
Cataldo Tirolo
Nunzio Testa
Salvatore Caniglia
Carmela Giachino
Bianca Marchetti

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1596878

1,210 views

Systematic Review

Published on 09 Apr 2025

Identification of functional near-infrared spectroscopy for older adults with mild cognitive impairment: a systematic review

in Neurocognitive Aging and Behavior

Bo Yang
Xia Deng
Xianfeng Qu
Yingjie Li
Lei Guo
Nengwei Yu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1492800

3,703 views

Original Research

Published on 09 Apr 2025

Knowledge of Parkinson’s disease among non-PD specialists: a web-based survey in South China

in Parkinson’s Disease and Aging-related Movement Disorders

Shaohua Lyu
Zhe Li
Zhenhui Mao
Jingbo Sun
Chunye Zheng
Qiaozhen Su

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1488009

2,825 views

Original Research

Published on 09 Apr 2025

Machine learning study on predicting depressive symptoms and genetic correlations in Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Haijun Zhang
Yifan Zhang
Guihua Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1584005

2,523 views

Original Research

Published on 09 Apr 2025

Correlation of cognitive impairment with Mediterranean diet and mortality: a prospective cohort study

in Neurocognitive Aging and Behavior

Ling Li
Xiaoxiao Zheng
Hongyue Ma
Mingxia Zhu
Xiuli Li
Xinhong Feng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1556608

3,475 views
1 citation

Review

Published on 08 Apr 2025

Alzheimer's disease and insomnia: a bibliometric study and visualization analysis

in Neurocognitive Aging and Behavior

Zi-Yue Tian
Bing Jiang
Meng Jin
Xiao-Kun Yu
Qi-Lin Chen
Jia-Hui Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1542607

6,063 views
3 citations

Original Research

Published on 08 Apr 2025

Predictors of white matter hyperintensities in the elderly Congolese population

in Alzheimer's Disease and Related Dementias

Emile Omba Yohe
Alvaro Alonso
Daniel L. Drane
Saranya Sundaram Patel
Megan Schwinne
Emmanuel Epenge
Guy Gikelekele
Esambo Herve
Immaculee Kavugho
Nathan Tshengele

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1491477

2,450 views
1 citation

Review

Published on 08 Apr 2025

Research progress on resistance exercise therapy for improving cognitive function in patients with AD and muscle atrophy

in Neurocognitive Aging and Behavior

Wenyao Li
Wei Fang
Yier Zhang
Qiulu Chen
Wuyue Shentu
Qilun Lai
Lin Cheng
Sicheng Yan
Qi Kong
Song Qiao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1552905

6,215 views
3 citations

Editorial

Published on 07 Apr 2025

Editorial: Recent advances in research on cognitive frailty and related conditions

in Neurocognitive Aging and Behavior

Takao Yamasaki
Mutsuhide Tanaka
Shuzo Kumagai

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1595526

3,863 views
2 citations

Original Research

Published on 07 Apr 2025

Substantia nigra and blood gene signatures and biomarkers for Parkinson’s disease from integrated multicenter microarray-based transcriptomic analyses

in Parkinson’s Disease and Aging-related Movement Disorders

Hui-Hui Fan
Na-Na Hou
Dao-Lu Zhang
Dan-Ni Liu
Rong-Ting Tang
Hai-Tao Luo
Ya-Dan Song
Lei Cui
Xiong Zhang
Jian-Hong Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1540830

3,148 views
3 citations

Original Research

Published on 07 Apr 2025

Calcineurin-mediated regulation of growth-associated protein 43 is essential for neurite and synapse formation and protects against α-synuclein-induced degeneration

in Alzheimer's Disease and Related Dementias

Ekaterina Grebenik
Sofia Zaichick
Gabriela Caraveo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1566465

2,520 views
5 citations

Original Research

Published on 04 Apr 2025

Exploring the link between estimated glucose disposal rate and Parkinson’s disease: cross-sectional and mortality analysis of NHANES 2003–2016

in Parkinson’s Disease and Aging-related Movement Disorders

Xiaoting Li
Zhaohao Zeng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1548020

4,333 views
4 citations

Review

Published on 04 Apr 2025

Aerobic exercise, an effective intervention for cognitive impairment after ischemic stroke

in Neurocognitive Aging and Behavior

Mingjin Zhu
Wenjun Chen
Jie Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1514271

9,640 views
4 citations

Original Research

Published on 04 Apr 2025

Galangin reduces MPTP-induced dopamine neuron injury via the autophagy dependent-PI3K/AKT pathway

in Parkinson’s Disease and Aging-related Movement Disorders

Liping Huang
Qiaofeng Li
Jingyi Wu
Yingying He
Junwei Huang
Sipeng Xie
Canfeng Yang
Qingling Ruan
Zhongliu Zhou
Minzhen Deng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1568002

3,802 views
4 citations

Original Research

Published on 03 Apr 2025

Mapping the scientific research on exercise therapy for Alzheimer’s disease: a scientometric study of hotspots and emerging trends

in Alzheimer's Disease and Related Dementias

Shi Long Song
Wen Bing Yu
Xin Min Cai
Jie Ma
Lu Lu Zou
Li Li Gao
Shi Ming Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1536515

4,123 views

Original Research

Published on 03 Apr 2025

Lifetime estrogen exposure and domain-specific cognitive performance: results from the IGNITE study

in Neurocognitive Aging and Behavior

Amber Watts
Shannon Donofry
Hayley Ripperger
Nicole M. Eklund
Lu Wan
Chaeryon Kang
George Grove
Lauren E. Oberlin
Swathi Gujral
Eric D. Vidoni

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1524474

5,019 views
1 citation

Original Research

Published on 02 Apr 2025

Evaluation of the efficacy of Tai Chi on the cognitive function of patients with mild cognitive dysfunction and research on its mechanism

in Neurocognitive Aging and Behavior

Lin Lin
Yao-Xi He
Quan Wen
Jia-Yang Liu
Yu Dai
Yu-Zhe Fei
Hang Li
Chang-Qing Li
Huan Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1435996

4,350 views
5 citations

Original Research

Published on 02 Apr 2025

Synapses-associated research in Parkinson’s disease: an explored trends analysis

in Parkinson’s Disease and Aging-related Movement Disorders

Yan-Jun Chen
Ming-Rong Xie
Sheng-Qiang Zhou
Fang Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1537119

2,542 views
4 citations

Original Research

Published on 31 Mar 2025

Allostatic load, a measure of cumulative physiological stress, impairs brain structure but not β-accumulation in older adults: an exploratory study

in Alzheimer's Disease and Related Dementias

Cassandre Palix
Léa Chauveau
Francesca Felisatti
Anne Chocat
Laurent Coulbault
Oriane Hébert
Florence Mézenge
Brigitte Landeau
Sacha Haudry
Séverine Fauvel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1508677

6,767 views
5 citations

Original Research

Published on 31 Mar 2025

Serine-129 phosphorylated α-synuclein drives mitochondrial dysfunction and calcium dysregulation in Parkinson’s disease model

in Neurocognitive Aging and Behavior

Jie Jiao
Weijin Liu
Ge Gao
Hui Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1538166

5,308 views
6 citations

Original Research

Published on 28 Mar 2025

Higher dietary butyrate intake is associated with better cognitive function in older adults: evidence from a cross-sectional study

in Alzheimer's Disease and Related Dementias

Jiayu Tu
Jun Zhang
Gang Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1522498

7,133 views
11 citations

7,819 articles

articles

Baicalein ameliorates cognitive decline induced by chronic cerebral hypoperfusion through the SIRT1-mediated Notch1 pathway to improve angiogenesis and suppress neuroinflammation

Explainable graph neural network based on metabolic brain imaging for differential diagnosis of parkinsonism

Frontotemporal dementia: a systematic review of artificial intelligence approaches in differential diagnosis

Corrigendum: Boosting antioxidant self-defenses by grafting astrocytes rejuvenates the aged microenvironment and mitigates nigrostriatal toxicity in parkinsonian brain via an Nrf2-driven Wnt/β-catenin prosurvival axis

Identification of functional near-infrared spectroscopy for older adults with mild cognitive impairment: a systematic review

Knowledge of Parkinson’s disease among non-PD specialists: a web-based survey in South China

Machine learning study on predicting depressive symptoms and genetic correlations in Parkinson’s disease

Correlation of cognitive impairment with Mediterranean diet and mortality: a prospective cohort study

Alzheimer's disease and insomnia: a bibliometric study and visualization analysis

Predictors of white matter hyperintensities in the elderly Congolese population

Research progress on resistance exercise therapy for improving cognitive function in patients with AD and muscle atrophy

Editorial: Recent advances in research on cognitive frailty and related conditions

Substantia nigra and blood gene signatures and biomarkers for Parkinson’s disease from integrated multicenter microarray-based transcriptomic analyses

Calcineurin-mediated regulation of growth-associated protein 43 is essential for neurite and synapse formation and protects against α-synuclein-induced degeneration

Exploring the link between estimated glucose disposal rate and Parkinson’s disease: cross-sectional and mortality analysis of NHANES 2003–2016

Aerobic exercise, an effective intervention for cognitive impairment after ischemic stroke

Galangin reduces MPTP-induced dopamine neuron injury via the autophagy dependent-PI3K/AKT pathway

Mapping the scientific research on exercise therapy for Alzheimer’s disease: a scientometric study of hotspots and emerging trends

Lifetime estrogen exposure and domain-specific cognitive performance: results from the IGNITE study

Evaluation of the efficacy of Tai Chi on the cognitive function of patients with mild cognitive dysfunction and research on its mechanism

Synapses-associated research in Parkinson’s disease: an explored trends analysis

Allostatic load, a measure of cumulative physiological stress, impairs brain structure but not β-accumulation in older adults: an exploratory study

Serine-129 phosphorylated α-synuclein drives mitochondrial dysfunction and calcium dysregulation in Parkinson’s disease model

Higher dietary butyrate intake is associated with better cognitive function in older adults: evidence from a cross-sectional study