Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Original Research

Accepted on 22 Aug 2025

Abnormal resting-state EEG neural oscillations and functional Connectivity in mild cognitive impairment

in Alzheimer's Disease and Related Dementias

Yi Jiang
Zhiwei Guo
Rubing Jiao
Haoru He
Ning Jiang
Jiayuan He

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1640966

122 views

Original Research

Published on 22 Aug 2025

Moderating role of triglycerides in the relationship between amyloid-β, hippocampal atrophy, and cognitive decline in mild cognitive impairment and early Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Ji-Woo Seok
Kahye Kim
Soonjo Hwang
Kun Ho Lee
Jaeuk U. Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1592341

392 views

Original Research

Accepted on 21 Aug 2025

The mediating role of depression on the association between physical activity and cognitive function among older adults

in Alzheimer's Disease and Related Dementias

HuanRui Zhang
Wen Tian
Guoxian Qi
XiuFang Wei

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1470256

Review

Accepted on 20 Aug 2025

Exercise-Mediated Cerebrovascular Repair in Alzheimer's Disease: From Pathophysiology to Therapeutic Precision

in Alzheimer's Disease and Related Dementias

Jingyun Hu
Ming Cai
Keren Cai
Ziqi Wei
Jing Zhou
Jiayi Shu
Weiyi Wang
Wanju Sun

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1632365

135 views

Original Research

Published on 20 Aug 2025

Virtual reality navigation for the early detection of Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Sayuri Shima
Reiko Ohdake
Yasuaki Mizutani
Harutsugu Tatebe
Riki Koike
Atsushi Kasai
Epifanio Bagarinao
Kazuya Kawabata
Akihiro Ueda
Mizuki Ito

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1571429

574 views

Original Research

Published on 20 Aug 2025

Disrupted calcium dynamics and electrophysiological activity in the stratum pyramidale and hippocampal alveus during fear conditioning in the 5xFAD model of Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Alexander Erofeev
Egor Vinokurov
Anastasia Bol’shakova
Ilya Bezprozvanny
Olga Vlasova

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1550673

484 views

Original Research

Published on 18 Aug 2025

Accelerated midlife endocrine and bioenergetic brain aging in APOE4 females

in Alzheimer's Disease and Related Dementias

Tian Wang
Zisu Mao
Yuan Shang
Simona Merlini
Francesca Vitali
Jean-Paul Wiegand
Roberta Diaz Brinton

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1632877

1,035 views

Original Research

Published on 18 Aug 2025

Accurate and robust prediction of Amyloid-β brain deposition from plasma biomarkers and clinical information using machine learning

in Alzheimer's Disease and Related Dementias

Jiayuan Xu
Andrew J. Doig
Sofia Michopoulou
Petroula Proitsi
Fumie Costen
The Alzheimer's disease neuroimaging initiative

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1559459

559 views

Review

Published on 15 Aug 2025

Naringenin as a neurotherapeutic agent in Alzheimer’s disease: epigenetic signatures, gut microbiota alterations, and molecular neuroprotection

in Alzheimer's Disease and Related Dementias

Zhenzhen Lai
Long Ke
Wei Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1647967

795 views

Review

Published on 15 Aug 2025

Artificial intelligence technologies for enhancing neurofunctionalities: a comprehensive review with applications in Alzheimer’s disease research

in Alzheimer's Disease and Related Dementias

Zhirong Gu
Bin Ge
Yuanyuan Wang
Yiping Gong
Mei Qi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1609063

1,083 views

Mini Review

Published on 14 Aug 2025

Exploring efficient and effective mammalian models for Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Mitsunori Kayano

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1652754

589 views

Original Research

Published on 12 Aug 2025

Local gyrification index and sulcal depth as imaging markers of cognitive decline in Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Yongsik Sim
Changmin Seo
Young-gun Lee
Byoung Seok Ye
Ilwoo Lyu
Beomseok Sohn

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1635861

514 views

Review

Accepted on 08 Aug 2025

The Manipulator Behind "Scissors": γ-Secretase and Its Modulators in Alzheimer's Disease

in Alzheimer's Disease and Related Dementias

Ning Gao
Fan Xing
Juan Du
Wenxue Zhao
Sijia Wang
Meinei Chen
Xiaolong Dong
Yiming Qi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1637671

470 views

Original Research

Accepted on 07 Aug 2025

Associations of plasma von Willebrand Factor levels with cognitive decline and neurodegeneration in older adults without dementia

in Alzheimer's Disease and Related Dementias

Pan Fu
Meiling Hu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1595071

183 views

Original Research

Accepted on 07 Aug 2025

Abnormal sleep blood pressure patterns are associated with diffusion tensor imaging along perivascular spaces index in cognitively impaired individuals

in Alzheimer's Disease and Related Dementias

Mariateresa Buongiorno
Gonzalo Sánchez-Benavides
Giovanni Caruana
Andrea Elias
Cristina Artero
Natalia Cullell
Pilar Delgado
Darly Milena Giraldo
Clara Marzal
Oriol Grau-Rivera

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1578270

134 views

Original Research

Published on 06 Aug 2025

Effect of aspirin use on conversion risk from mild cognitive impairment to Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Bo Kyu Choi
Yeonju Jin
Hokyung Lee
Sung-Woo Kim
Sojeong Park
Ickpyo Hong
Min Seok Baek

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1603892

781 views