Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Original Research

Accepted on 03 Nov 2025

Dysfunctional Default Mode and Visual Networks Underlie Cognitive Deficits in Dementia With Lewy Bodies: A Resting-State fMRI Study

in Alzheimer's Disease and Related Dementias

Zhou Su
Jun Kuai
Tingting Yi
Yuechang Zheng
Xinran Bao
Jiyu Ji

Frontiers in Aging Neuroscience

Original Research

Published on 31 Oct 2025

Spatial transcriptomics reveals an unexpected impact of tau and tau pathology on the expression of transthyretin

in Alzheimer's Disease and Related Dementias

Deborah L. Croteau
Jose Fernandez Navarro
Thomas Comptdaer
Zaneta Andrusivova
Aleksandra Jurek
Eliette Bonnefoy
Luc Buée
Vilhelm A. Bohr
Joakim Lundeberg
Marie-Christine Galas

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1656850

857 views

Review

Accepted on 30 Oct 2025

Unvalidated Efficacy and Significant Risks Hinder Clinical Use of Deep Cervical Lymphatic-Venous Anastomosis for Alzheimer's Disease

in Alzheimer's Disease and Related Dementias

Rui Zhang
Xinjun Li

Frontiers in Aging Neuroscience

Review

Accepted on 30 Oct 2025

Structural and Microstructural Changes in White and Grey Matter Across the Alzheimer Disease Continuum

in Alzheimer's Disease and Related Dementias

Lingling Lv
Hui Guo
Zhiru zhao
Xiongfei Zhao

Frontiers in Aging Neuroscience

Original Research

Accepted on 28 Oct 2025

MRI-derived global small vessel disease burden serves as markers of hippocampal sclerosis and clinical stage across the probable Alzheimer's disease continuum

in Alzheimer's Disease and Related Dementias

Ya-Che Chen
Ting-Bin Chen
Hsin-Chieh Chen

Frontiers in Aging Neuroscience

407 views

Original Research

Accepted on 27 Oct 2025

Evaluation of Microcurrent as an Adjunct to Donepezil Therapy in an Alzheimer's Disease Mouse Model: A Pilot Study

in Alzheimer's Disease and Related Dementias

Eun Ho Kim
Yoon-Jin Lee
Yong Suk Moon
Oh Dae Kwon
Dong Rak Kwon

Frontiers in Aging Neuroscience

146 views

Original Research

Accepted on 27 Oct 2025

Clinical and neuropsychological features associated with progression in subjective cognitive decline

in Alzheimer's Disease and Related Dementias

Rafael Villino
Mirla Ríos-Rivera
Genoveva Montoya-Murillo
Jonathan Patricio Baldera
Salomón Salaza-Londoño
Maria Cruz Rodríguez-Oroz
Miguel German Borda
Adolfo Jimenez-Huete
Mario Riverol

Frontiers in Aging Neuroscience

160 views

Review

Accepted on 27 Oct 2025

THE PATHOBIOME-NEURODEGENERATION AXIS: TROPICAL INFECTIOUS AGENTS, GUT MICROBIOME PERTURBATIONS, AND ALZHEIMER'S DISEASE PATHOGENESIS

in Alzheimer's Disease and Related Dementias

Edward Jenner Tettevi
David Larbi Simpong
Frank Adu-Nti
Lawrencia Osae-Nyarko
Mike Yaw Osei-Atweneboana

Frontiers in Aging Neuroscience

166 views

Original Research

Accepted on 27 Oct 2025

Music-Induced Physiological Markers for Alzheimer's Disease Detection Using Machine Learning

in Alzheimer's Disease and Related Dementias

Rodrigo Lima
Goncalo Barradas
Sergi Bermúdez i Badia

Frontiers in Aging Neuroscience

152 views

Original Research

Accepted on 27 Oct 2025

Intracranial self‐stimulation mitigates spatial task deficits, modifies miR‐146a and miR‐495 serum levels and restores hippocampal NRF2 levels in a rat model of sporadic Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Andrea Riberas-Sánchez
Soleil García-Brito
Laia Vila-Solés
Laura Aldavert-Vera
Pilar Segura-Torres
Gemma Huguet
Gemma Carreras-Badosa
Elisabet Kadar

Frontiers in Aging Neuroscience

213 views

Original Research

Published on 27 Oct 2025

Multimodal radiomics of cerebellar subregions for machine learning-driven Alzheimer’s disease diagnosis

in Alzheimer's Disease and Related Dementias

Xinqing Hao
Ying Li
Xiulin Wang
Changjun Ma
Ruichen Liu
Yang Jiao
Chunbo Dong
Jing Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1679788

421 views

Original Research

Accepted on 24 Oct 2025

Integrated Analysis of N-Glycosylation and Alzheimer's Disease: Identifying Key Biomarkers and Mechanisms

in Alzheimer's Disease and Related Dementias

Zhang hao
Chen wen jun
Yuan shu you
Cai bo
Ding shao xiang
Bao hong xia
Sun jun kai
Lu Wei
Zhu hao gang

Frontiers in Aging Neuroscience

414 views

Correction

Accepted on 24 Oct 2025

Five-year dementia prediction and decision support system based on real-world data

in Alzheimer's Disease and Related Dementias

Themis Exarchos
George A Dimakopoulos
Konstantinos Lazaros
Marios Krokidis
Aristidis Vrahatis
Gerasimos Grammenos
Antigoni Avramouli
Konstantina Skolariki
Roy Adams
VASILIKI MACHAIRAKI

Frontiers in Aging Neuroscience

277 views

Review

Accepted on 22 Oct 2025

Exercise Modulation of Gut Microbiota in Alzheimer's Disease: Pathophysiological Mechanisms and Therapeutic Perspectives

in Alzheimer's Disease and Related Dementias

Si-yi Leng
Qi-Hang Yang
Yang Yuan
Bingao Chen
Hongbao Chen
Weikang Ban
Jiahao Zhang

Frontiers in Aging Neuroscience

579 views

Editorial

Published on 22 Oct 2025

Editorial: Current chemical approaches in combating neuroinflammation in Alzheimer's disease (AD)

in Alzheimer's Disease and Related Dementias

Sayan Roy Chowdhury
Venkatesh Katari
Dwaipayan Sen
Prasenjit Mondal

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1712601

573 views

Original Research

Published on 22 Oct 2025

Baseline CSF ferritin levels were associated with trajectories of depressive symptoms among older people without dementia

in Alzheimer's Disease and Related Dementias

Qing Wang
Xinwu Ye
Yongjian Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1516388

454 views