Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Mini Review

Accepted on 31 Jul 2025

Exploring efficient and effective mammalian models for Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Mitsunori Kayano

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1652754

125 views

Original Research

Accepted on 29 Jul 2025

Longitudinal multimodal MRI analysis of lecanemab treatment in mild cognitive impairment: a pilot study of structural, perfusion, and microstructural changes

in Alzheimer's Disease and Related Dementias

TOSHIYA TAKAHASHI
Thuy Ha Duy Dinh
Shingo Takenaka
Sayaka Ono
Maya Fukui
Yasushi Okada
Ｔomohiko Asada
Kan Niimi
Kaku Kimura
Akio Ikeda

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1651596

215 views

Review

Accepted on 28 Jul 2025

Artificial Intelligence Technologies for Enhancing Neurofunctionalities: A Comprehensive Review with Applications in Alzheimer’s Disease Research

in Alzheimer's Disease and Related Dementias

Zhirong Gu
Yuanyuan Wang
Yuanyuan Wang
Yiping Gong
Mei Qi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1609063

435 views

Original Research

Accepted on 28 Jul 2025

Virtual Reality Navigation for the Early Detection of Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Sayuri Shima
Reiko Ohdake
Yasuaki Mizutani
Harutsugu Tatebe
Riki Koike
Atsushi Kasai
Epifanio Bagarinao
Akihiro Ueda
Mizuki Ito
Junichi Hata

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1571429

214 views

Original Research

Accepted on 28 Jul 2025

Local Gyrification Index and Sulcal Depth as Imaging Markers of Cognitive Decline in Alzheimer's Disease

in Alzheimer's Disease and Related Dementias

Yongsik Sim
Changmin Seo
Young-gun Lee
Byoung Seok Ye
Ilwoo Lyu
Beomseok Sohn

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1635861

136 views

Original Research

Published on 28 Jul 2025

Multimodal DTI-ALPS and hippocampal microstructural signatures unveil stage-specific pathways in Alzheimer’s disease progression

in Alzheimer's Disease and Related Dementias

Peng Yu
Lu Shen
Lijun Tang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1609793

607 views

Original Research

Accepted on 25 Jul 2025

Effect of Aspirin Use on Conversion Risk from Mild Cognitive Impairment to Alzheimer's Disease

in Alzheimer's Disease and Related Dementias

Bo Kyu Choi
Yeonju Jin
Hokyung Lee
Sung-Woo Kim
Sojeong Park
Ickpyo Hong
Min Seok Baek

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1603892

237 views

Review

Accepted on 24 Jul 2025

Advancement in Modelling of Alzheimer's Disease: A Comprehensive Review of Preclinical Screening Platforms

in Alzheimer's Disease and Related Dementias

Souvik Adak
Shivam Singh
Ridhi Jain
Abhilasha Tiwari
Binny Singh
Sumit Kumar
Ayushi Dadhwal
Avishek Chakroborty
Ashish Kumar Sharma
Ravindra Pal Singh

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1646551

306 views

Original Research

Accepted on 24 Jul 2025

Bioinformatics and experimental validation identify biomarkers for diagnosing Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Hui Liu
Chenye Li
Congchen Zhai
Mei Li
Lan Ma

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1566929

272 views

Review

Accepted on 24 Jul 2025

Naringenin as a neurotherapeutic agent in Alzheimer's disease: Epigenetic signatures, gut microbiota alterations, and molecular neuroprotection

in Alzheimer's Disease and Related Dementias

Long Ke

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1647967

201 views

Original Research

Accepted on 24 Jul 2025

Accelerated Midlife Endocrine and Bioenergetic Brain Aging in APOE4 Females

in Alzheimer's Disease and Related Dementias

Tian Wang
Zisu Mao
Yuan Shang
Simona Merlini
Francesca Vitali
Jean-Paul Wiegand
Roberta Diaz Brinton

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1632877

291 views

Original Research

Published on 24 Jul 2025

Estimating progression of Alzheimer’s disease with extracellular vesicle-related multi-omics risk models

in Alzheimer's Disease and Related Dementias

Xiao Zhang
Sanoji Wijenayake
Shakhawat Hossain
Qian Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1617611

909 views

Mini Review

Published on 24 Jul 2025

GLP-1R as a potential link between diabetes and Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Shujun Li
Nanqu Huang
Mei Wang
Wendi Huang
Jingshan Shi
Yong Luo
Juan Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1601602

757 views

Original Research

Accepted on 23 Jul 2025

Accurate and Robust Prediction of Amyloid-B Brain Deposition from Plasma Biomarkers and Clinical Information Using Machine Learning

in Alzheimer's Disease and Related Dementias

Jiayuan Xu
Andrew J Doig
Sofia Michopoulou
Petroula Proitsi
Fumie Costen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1559459

216 views

Review

Published on 23 Jul 2025

Tau and tauopathies across primate species: implications for modeling neurodegenerative disorders

in Alzheimer's Disease and Related Dementias

Julia C. Colwell
Marina E. Emborg

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1598245

624 views

Original Research

Published on 23 Jul 2025

Region-informed machine learning model for choroid plexus segmentation in Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Liangdong Zhou
Tracy A. Butler
Xiuyuan H. Wang
Samantha A. Keil
Seyed Hani Hojjati
Tsung-Wei Hu
Mélissa Savard
Firoza Z. Lussier
Pedro Rosa-Neto
Lidia Glodzik

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1613320

710 views