Frontiers in Aging Neuroscience | Neuroinflammation and Neuropathy

Hypothesis and Theory

Accepted on 28 Oct 2025

The Interplay of Homeostasis, Inflammation, and Oxidative Stress in Neurodegenerative Disorders: The Role of Biological Markers, Antioxidants, Lithium, and TMS — A Proposed Framework for Preventing Neurodegenerative Disorders Through Biomarkers and Multimodal Therapies

in Neuroinflammation and Neuropathy

Leonard Lado, MD, ABPN, RPh
Aruna Misir, Medical Student and Researcher

Frontiers in Aging Neuroscience

Original Research

Accepted on 27 Oct 2025

Mediating Role of Muscle Quality in the Liver–Brain Axis: Integrated Analysis of CT Markers of Body Composition, Brain Aging, and Biomarkers

in Neuroinflammation and Neuropathy

Minchul Kim
Chongwon Pae
Joon Ho Moon
Inpyeong Hwang
Kyu Sung Choi

Frontiers in Aging Neuroscience

135 views

Editorial

Published on 27 Oct 2025

Editorial: Neuroinflammation and distribution of proinflammatory markers in the brain

in Neuroinflammation and Neuropathy

Huazheng Liang
Yong Hao
Yong Bi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1723530

390 views

Original Research

Accepted on 23 Oct 2025

Astrocytic Ror2-induced imbalance in brain and gut homeostasis contributes to chronic post-thoracotomy pain

in Neuroinflammation and Neuropathy

Chaoqun Liu
Le Shen
Li Xu
Afang Zhu
Yuguang Huang

Frontiers in Aging Neuroscience

348 views

Review

Accepted on 23 Oct 2025

Brain microenvironment orchestrates highly aggressive tumor variants: current trends and therapeutic approaches

in Neuroinflammation and Neuropathy

Juhi Mishra
John D Dickinson
Shailendra Kumar Maurya

Frontiers in Aging Neuroscience

364 views

Review

Accepted on 20 Oct 2025

Research progress on the role of microbiome-immune-neurotransmitter network in post-stroke sleep disorders

in Neuroinflammation and Neuropathy

Wanting Shi
Li Wu
Qiong Qin
Yanjing Li
Wei Chen

Frontiers in Aging Neuroscience

365 views

Original Research

Accepted on 20 Oct 2025

Dynamic Decline in Estimated Glomerular Filtration Rate Associated with In-Hospital Mortality Risk in Acute Ischemic Stroke Patients After Endovascular Therapy: Evidence from a Chinese Stroke Center

in Neuroinflammation and Neuropathy

Yanping Lin
Jingjing She
Lijuan Cai
Lingfeng Yu
Shouyue Jin
Xingyu Chen
Renjing Zhu
Weiwei Gao

Frontiers in Aging Neuroscience

318 views

Review

Published on 02 Oct 2025

Role of lipocalin-2 in amyotrophic lateral sclerosis

in Neuroinflammation and Neuropathy

Zhuoya Wang
Wen Cao
Dongsheng Fan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1672903

1,798 views

Original Research

Published on 01 Oct 2025

Western diet-induced visceral adipose tissue inflammation promotes Alzheimer’s disease pathology via microglial activation in a mouse model

in Neuroinflammation and Neuropathy

Ji Sun Lim
Soyoung Kwak
Mi-Hee Yu
Mee-Na Park
Hye Suk Baek
Junho Kang
Jeong-Ho Hong
Jin Kyung Kim
Hye Won Lee
Sang-Woo Lee

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1644988

1,417 views

Mini Review

Published on 25 Sep 2025

Role of store-operated Ca2+ entry and STIM2 in retinal neurodegeneration during glaucoma

in Neuroinflammation and Neuropathy

Sofiia Baranykova

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1657590

2,032 views

Opinion

Published on 24 Sep 2025

Regulatory mechanisms of neuro inflammation from a gender perspective: interactions among astrocytes, sex hormones, and the gut-brain axis

in Neuroinflammation and Neuropathy

Jia-Wei Shi
Xiu-Li Meng
Yu Ye
Yi-Ting Wang
He-Xuan Ding
Wen-Xu Qi
Rui Feng
Ke Zhang
Ming Lei

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1675694

1,747 views

Original Research

Published on 23 Sep 2025

The impact of ondansetron on clinical outcomes in cranial surgery patients: a propensity-matched analysis of retrospective data

in Neuroinflammation and Neuropathy

Debo Yun
Yongzhen Luo
Rui Li
Wenyong Li
Chunyou Wan
Qinjiang Huang
Jiang Du
Shiyi Zeng
Guangdong Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1627353

1,876 views

General Commentary

Published on 11 Sep 2025

Commentary: Sensorimotor dysfunction and postural instability in older adults with type 2 diabetes mellitus: the role of proprioception and neuropathy

in Neuroinflammation and Neuropathy

Datian Chen
Hui Gong

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1658306

2,015 views

Review

Published on 08 Sep 2025

Cognitive deterioration in patients undergoing hemodialysis: how variations in age influence the development of new mechanisms and treatment approaches?

in Neuroinflammation and Neuropathy

Hongyu Jiang
Dongyuan He
Yue Hu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1645702

1,928 views

Mini Review

Published on 01 Sep 2025

The estrogen–brain interface in neuroinflammation: a multidimensional mechanistic insight

in Neuroinflammation and Neuropathy

Jie Lu
Tie-Jun Xian
Cheng-Jun Li
Yang Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1671552

2,096 views
1 citation

Original Research

Published on 29 Aug 2025

Systemic inflammation versus clinical demographics: patient age surpasses the platelet-to-lymphocyte ratio in differentiating secondary trigeminal neuralgia

in Neuroinflammation and Neuropathy

Zihao Zhang
Qingpei Hao
Tao Wang
Shijun Peng
Xin Chang
Yuepeng Wang
Jia Ouyang
Ruen Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1658854

1,101 views