Frontiers in Aging

Brief Research Report

Accepted on 05 Jan 2026

Age-related hearing loss in healthy older adults is associated with arterial stiffening and higher aortic systolic blood pressure: potential role of inflammation

in Healthy Longevity

Nicholas Anthony Carlini
Lynn M. Bielski
Courtney N. Mudd
Taylor C. Harman-Hornbeck
Matthew P. Harber
Bradley S. Fleenor

Frontiers in Aging

222 views

Brief Research Report

Published on 05 Jan 2026

Interplay between oxidative stress and physical exercise in hospitalized older adults: a secondary analysis of an RCT using malondialdehyde as a biomarker

in Molecular Mechanisms of Aging

Chenhui Chenhuichen
Pedro Azanon-Nogueira
Maite Izco-Cubero
Iciar Echeverria-Beistegui
Patricia Alvarez-Rodriguez
Fabíola Zambom-Ferraresi
Fabricio Zambom-Ferraresi
Marisa Fernández González De La Riva
Consuelo Borrás
Nicolas Martínez-Velilla

Frontiers in Aging

doi 10.3389/fragi.2025.1708162

871 views

Systematic Review

Published on 05 Jan 2026

Impact of digital health interventions on quality of life and mental health in older adults with chronic diseases: a systematic review and meta-analysis

in Interventions in Aging

Enliang Hu
Haozhe Wang
Jiayi Yao
Mingyu Liao
Wenjia Chen

Frontiers in Aging

doi 10.3389/fragi.2025.1737277

1,060 views
1 citation

Editorial

Published on 02 Jan 2026

Editorial: Application of bioinformatics, machine learning, and artificial intelligence to improve diagnosis, prognosis and treatment of cancer

in Aging and Cancer

Tinka Vidović
Petar Ozretić

Frontiers in Aging

doi 10.3389/fragi.2025.1763491

990 views

Review

Accepted on 26 Dec 2025

The gut and circulating virome: emerging players in aging and longevity

in Aging and the Immune System

Gretta Veronica Badillo-Pazmay
Carlo Fortunato
Laura Cianfruglia
Federica Novazzi
Pietro Giorgio Spezia
Luigi Rosa
Dolores Limongi
Carla Prezioso
Valeria D'Argenio
Olga Scudiero

Frontiers in Aging

485 views

Clinical Trial

Published on 19 Dec 2025

Trans-resveratrol reduces visible signs of skin ageing in healthy adult females over 40: an 8-week randomized placebo-controlled trial

in Healthy Longevity

Amanda Rao
David Briskey
Georgia Roche
Annie Tremblay
Marcia Da Silva Pinto
Thomas A. Tompkins

Frontiers in Aging

doi 10.3389/fragi.2025.1727244

7,152 views

Original Research

Published on 19 Dec 2025

CD38 promotes LPS-induced innate-like activation and proliferation of CD8+ T lymphocytes in aged mice

in Aging and the Immune System

Wendolaine Santiago-Cruz
Enrique Espinosa
Jocelyn C. Pérez-Lara
Héctor Romero-Ramírez
Priyadharshini Devarajan
Fabio García-García
Juan C. Rodríguez-Alba

Frontiers in Aging

doi 10.3389/fragi.2025.1701685

1,521 views

Review

Published on 19 Dec 2025

Dietary phenolics and exercise complementation to delay aging at its source: a comprehensive review highlighting mitochondrial function

in Interventions in Aging

Jiong Zhang
Wen-Wen Zhu
Yong-Yao Huang
Chuan-He Tang

Frontiers in Aging

doi 10.3389/fragi.2025.1693043

1,291 views

Opinion

Published on 18 Dec 2025

Ethical and logistical imperatives for AI-driven cardiovascular risk prediction among older adults in Tanzania: framing a digital health agenda for low-income settings

in Interventions in Aging

Innocent Arnold Tesha

Frontiers in Aging

doi 10.3389/fragi.2025.1673926

946 views

Review

Published on 18 Dec 2025

Methylation and algorithms in biological aging: a scoping review

in Aging and the Immune System

Alison Ziesel
Jennifer Reeves
Anastasia Mallidou
Lorelei Newton
Ryan E. Rhodes
Jie Zhang
Theone Paterson
Hosna Jabbari

Frontiers in Aging

doi 10.3389/fragi.2025.1682873

1,247 views

Original Research

Published on 16 Dec 2025

Reasoning decline during aging under familiar and unfamiliar physics

in Healthy Longevity

Melissa Dexter
Hélène Grandchamp des Raux
Ori Ossmy

Frontiers in Aging

doi 10.3389/fragi.2025.1646655

4,478 views

Editorial

Published on 15 Dec 2025

Editorial: Hypertension and cardiorenal syndrome and their relationship with aging: friends and foes

in Aging, Metabolism and Redox Biology

Humberto Muzi-Filho
Adalberto Vieyra

Frontiers in Aging

doi 10.3389/fragi.2025.1760202

675 views

Correction

Published on 12 Dec 2025

Correction: Preliminary research on the effect of sutra chanting on oral and respiratory function: a comparison between expert sutra chanting buddhist priests and general buddhist priests in Japan

in Healthy Longevity

Ayako Edahiro
Chiaki Ura
Yoshiko Motohashi
Ryosho Shoji
Reisai Kaneko
Yukan Ogawa
Akinori Takase
Kousho Nakano
Tsuyoshi Okamura

Frontiers in Aging

doi 10.3389/fragi.2025.1721074

4,510 views

Original Research

Published on 11 Dec 2025

Self-reported, functional, and objective health and sociodemographic characteristics among older adults in Kenya: findings from the pilot longitudinal study of health and ageing in Kenya (LOSHAK)

in Healthy Longevity

Eunice Muthoni Mwangi
James Orwa
Roselyter Monchari Riang’a
Niranjani Nagarajan
Felix Agoi
Patrick N. Mwangala
Alden L. Gross
Jean N. Ikanga
Kenneth M. Langa
Edward Miguel

Frontiers in Aging

doi 10.3389/fragi.2025.1693701

5,037 views

Original Research

Published on 11 Dec 2025

Age and liver transplantation: a key factor in clinical outcomes? single center study in Argentina

in Aging and the Immune System

Marco Santillán Pazmiño
Paula Constanza Arriola Benitez
Maria Florencia Fernandez
Silvina Yantorno
Valeria Descalzi
Franco Daniel Tarditti
María Lucia Novellis
Juan Cruz Fasolo
Martín Rumbo
Stefan Günther Tullius

Frontiers in Aging

doi 10.3389/fragi.2025.1729048

908 views

Editorial

Published on 11 Dec 2025

Editorial: (Un)healthy lifestyles, aging, and type 2 diabetes

in Interventions in Aging

Pedro Duarte-Mendes
Fernanda M. Silva
Ana M. Teixeira

Frontiers in Aging

doi 10.3389/fragi.2025.1696856

815 views

Original Research

Published on 10 Dec 2025

Impact of multicomponent home-based exercise on fear of falling in older people with a history of falls: insights from the GAITCARE project

in Musculoskeletal Aging

Elisabet Huertas-Hoyas
Marta Neira Álvarez
Agustín Curiel-Regueros
Luisa Ruiz-Ruiz
Rafael García-Molina
Cristina Alonso Bouzón
Eva Rincon-Herrera
Sara García De Villa
Antonio R. Jiménez-Ruiz

Frontiers in Aging

doi 10.3389/fragi.2025.1698917

731 views

Editorial

Published on 09 Dec 2025

Editorial: Insights in aging, metabolism and redox biology: 2024

in Aging, Metabolism and Redox Biology

Ruben K. Dagda
Jianhua Zhang

Frontiers in Aging

doi 10.3389/fragi.2025.1750125

1,312 views

Mini Review

Published on 05 Dec 2025

Toward precision longevity: aging interventions in the single-cell atlas era

in Interventions in Aging

Jason B. Chen
Miranda C. Wang
Shangyu Gong
Hongjie Li

Frontiers in Aging

doi 10.3389/fragi.2025.1674112

2,399 views

Review

Published on 04 Dec 2025

The intersection of TREX1, cGAS, STING and the DNA damage theory of aging

in Genetics, Genomics and Epigenomics of Aging

Kate M. Jones
Samuel D. Chauvin
Jonathan J. Miner

Frontiers in Aging

doi 10.3389/fragi.2025.1720372

1,920 views

Brief Research Report

Published on 01 Dec 2025

Epigenetic age acceleration and neurotrophin signaling pathways in cancer-related cognitive impairment: a longitudinal, prospective cohort study

in Genetics, Genomics and Epigenomics of Aging

Michael Sayer
Ding Quan Ng
Julia Trudeau
Raymond J. Chan
Munjal M. Acharya
Kord Kober
Alexandre Chan

Frontiers in Aging

doi 10.3389/fragi.2025.1667638

1,618 views

Review

Published on 27 Nov 2025

Single-cell multi-omics for precision cardiovascular and longevity medicine: from methods to clinical translation

in Healthy Longevity

Thiago Guimarães Osório
Estefania Pavesi
Khalil Abou El-Ardat
Needa Qureshi
Leanne Cassidy
Terrence Lee St. John
Nicole Sirotin
Bartlomiej Piechowski-Jozwiak

Frontiers in Aging

doi 10.3389/fragi.2025.1656727

6,906 views

Brief Research Report

Published on 27 Nov 2025

Bone mineral density and turnover response to GLP-1 receptor agonists in older adults with overweight/obesity and prediabetes/type 2 diabetes: a 20-week pilot trial post hoc analysis

in Musculoskeletal Aging

Lauren Dinkla
Kristen M. Beavers
Ronna Robbins
Dela Akpalu
Sarah J. Wherry
Gary Miller
Daniel P. Beavers
Sara Espinoza
Jonathan Trejo
Allison Stepanenko

Frontiers in Aging

doi 10.3389/fragi.2025.1691007

2,453 views

Original Research

Published on 27 Nov 2025

Celastrol attenuates diabetic kidney disease progression by repressing senescence of renal tubular epithelial cells

in Cellular Senescence

Yajun Zhang
Zewei Sun
Weixue Meng
Siqi Lei
Jingyong Sun
Yixuan Tang
Xiaodong Mu

Frontiers in Aging

doi 10.3389/fragi.2025.1657947

1,368 views

671 articles

articles

Age-related hearing loss in healthy older adults is associated with arterial stiffening and higher aortic systolic blood pressure: potential role of inflammation

Interplay between oxidative stress and physical exercise in hospitalized older adults: a secondary analysis of an RCT using malondialdehyde as a biomarker

Impact of digital health interventions on quality of life and mental health in older adults with chronic diseases: a systematic review and meta-analysis

Editorial: Application of bioinformatics, machine learning, and artificial intelligence to improve diagnosis, prognosis and treatment of cancer

The gut and circulating virome: emerging players in aging and longevity

Trans-resveratrol reduces visible signs of skin ageing in healthy adult females over 40: an 8-week randomized placebo-controlled trial

CD38 promotes LPS-induced innate-like activation and proliferation of CD8+ T lymphocytes in aged mice

Dietary phenolics and exercise complementation to delay aging at its source: a comprehensive review highlighting mitochondrial function

Ethical and logistical imperatives for AI-driven cardiovascular risk prediction among older adults in Tanzania: framing a digital health agenda for low-income settings

Methylation and algorithms in biological aging: a scoping review

Reasoning decline during aging under familiar and unfamiliar physics

Editorial: Hypertension and cardiorenal syndrome and their relationship with aging: friends and foes

Correction: Preliminary research on the effect of sutra chanting on oral and respiratory function: a comparison between expert sutra chanting buddhist priests and general buddhist priests in Japan

Self-reported, functional, and objective health and sociodemographic characteristics among older adults in Kenya: findings from the pilot longitudinal study of health and ageing in Kenya (LOSHAK)

Age and liver transplantation: a key factor in clinical outcomes? single center study in Argentina

Editorial: (Un)healthy lifestyles, aging, and type 2 diabetes

Impact of multicomponent home-based exercise on fear of falling in older people with a history of falls: insights from the GAITCARE project

Editorial: Insights in aging, metabolism and redox biology: 2024

Toward precision longevity: aging interventions in the single-cell atlas era

The intersection of TREX1, cGAS, STING and the DNA damage theory of aging

Epigenetic age acceleration and neurotrophin signaling pathways in cancer-related cognitive impairment: a longitudinal, prospective cohort study

Single-cell multi-omics for precision cardiovascular and longevity medicine: from methods to clinical translation

Bone mineral density and turnover response to GLP-1 receptor agonists in older adults with overweight/obesity and prediabetes/type 2 diabetes: a 20-week pilot trial post hoc analysis

Celastrol attenuates diabetic kidney disease progression by repressing senescence of renal tubular epithelial cells