Frontiers in Bioengineering and Biotechnology | Organoids and Organ-On-A-Chip

Original Research

Published on 02 Oct 2024

A millifluidic bioreactor allows the long term culture of primary lymphocytes or CD34+ hematopoietic cells while allowing the detection of tumorigenic expansion

in Organoids and Organ-On-A-Chip

Paolo Ritter
Stefania Oliveto
Chiara Cordiglieri
Alessandra Fasciani
Christian Andrea Di Buduo
Lucrezia della Volpe
Alberto Bocconi
Claudio Conci
Carolina Paula Miguel
Raffaella Di Micco

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1388312

2,333 views

Review

Published on 02 Oct 2024

Tumor-on-chip platforms for breast cancer continuum concept modeling

in Organoids and Organ-On-A-Chip

Anca-Narcisa Neagu
Danielle Whitham
Pathea Bruno
Nicholas Versaci
Peter Biggers
Costel C. Darie

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1436393

3,312 views
1 citation

Review

Published on 25 Sep 2024

Improving tumor microenvironment assessment in chip systems through next-generation technology integration

in Organoids and Organ-On-A-Chip

Daniela Gaebler
Stephanie J. Hachey
Christopher C. W. Hughes

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1462293

2,831 views
1 citation

Editorial

Published on 25 Sep 2024

Editorial: Emerging bioanalytical techniques and therapies for human disease models

in Organoids and Organ-On-A-Chip

Xuerui Wang
Jinnuo Lu
Yixiao Huang
Xinhao Liu
Guocheng Fang
Chih-Tsung Yang
Zhaobin Guo

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1453813

1,201 views

Original Research

Published on 06 Sep 2024

Bidirectionally validated in silico and in vitro formation of specific depth zone-derived chondrocyte spheroids and clusters

in Organoids and Organ-On-A-Chip

Eiichiro Takada
Hayato L. Mizuno
Yoshiki Takeoka
Shuichi Mizuno

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1440434

2,061 views

Original Research

Published on 02 Aug 2024

A multiparametric analysis including single-cell and subcellular feature assessment reveals differential behavior of spheroid cultures on distinct ultra-low attachment plate types

in Organoids and Organ-On-A-Chip

Mario Vitacolonna
Roman Bruch
Ane Agaçi
Elina Nürnberg
Tiziana Cesetti
Florian Keller
Francesco Padovani
Simeon Sauer
Kurt M. Schmoller
Markus Reischl

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1422235

4,096 views
1 citation

Original Research

Published on 25 Jun 2024

Optimization and validation of a fat-on-a-chip model for non-invasive therapeutic drug discovery

in Organoids and Organ-On-A-Chip

Lindsey K. Huff
Charles M. Amurgis
Lauren E. Kokai
Rosalyn D. Abbott

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1404327

2,423 views
1 citation

Original Research

Published on 12 Jun 2024

Cell identity dynamics and insight into insulin secretagogues when employing stem cell-derived islets for disease modeling

in Organoids and Organ-On-A-Chip

Chencheng Wang
Shadab Abadpour
Aleksandra Aizenshtadt
Andrea Dalmao-Fernandez
Merete Høyem
Ingrid Wilhelmsen
Justyna Stokowiec
Petter Angell Olsen
Stefan Krauss
Simona Chera

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1392575

6,810 views
1 citation

Review

Published on 24 May 2024

Progress and application of lung-on-a-chip for lung cancer

in Organoids and Organ-On-A-Chip

Lantao Li
Wentao Bo
Guangyan Wang
Xin Juan
Haiyi Xue
Hongwei Zhang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1378299

3,766 views
7 citations

Original Research

Published on 12 Apr 2024

In vitro co-culture of Clostridium scindens with primary human colonic epithelium protects the epithelium against Staphylococcus aureus

in Organoids and Organ-On-A-Chip

Hao Wang
Raehyun Kim
Yuli Wang
Kathleen L. Furtado
Christopher E. Sims
Rita Tamayo
Nancy L. Allbritton

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1382389

2,226 views
3 citations

Original Research

Published on 04 Apr 2024

Rational design of a near-infrared fluorescent probe for monitoring butyrylcholinesterase activity and its application in development of inhibitors

in Organoids and Organ-On-A-Chip

Hao Li
Xiao-Dong Li
Chao-Hua Yan
Zhen-Hua Ni
Mu-Han Lü
Li-Wei Zou
Ling Yang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1387146

2,034 views
4 citations

Original Research

Published on 03 Apr 2024

Single molecule studies of dynamic platelet interactions with endothelial cells

in Organoids and Organ-On-A-Chip

Fabian Hauser
Christoph Naderer
Eleni Priglinger
Anja Peterbauer
Michael B. Fischer
Heinz Redl
Jaroslaw Jacak

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1372807

2,282 views
1 citation

Review

Published on 28 Mar 2024

Revolutionizing nephrology research: expanding horizons with kidney-on-a-chip and beyond

in Organoids and Organ-On-A-Chip

Wei Huang
Yi-Yuan Chen
Fang-Fang He
Chun Zhang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1373386

6,478 views
5 citations

Original Research

Published on 18 Mar 2024

Evaluation of nanoparticle albumin-bound paclitaxel loaded macrophages for glioblastoma treatment based on a microfluidic chip

in Organoids and Organ-On-A-Chip

Zuorun Xie
Junyi Ye
Xinghua Gao
Hang Chen
Maosong Chen
Jiangfang Lian
Jingyun Ma
Hongcai Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1361682

3,094 views
2 citations

Mini Review

Published on 22 Feb 2024

Advances in exercise-induced vascular adaptation: mechanisms, models, and methods

in Organoids and Organ-On-A-Chip

Hualing Sun
Yanyan Zhang
Lijun Shi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1370234

3,479 views
4 citations

Specialty Grand Challenge

Published on 22 Feb 2024

Grand challenges in organoid and organ-on-a-chip technologies

in Organoids and Organ-On-A-Chip

Aleksander Skardal

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1366280

6,444 views
5 citations