Frontiers in Bioinformatics | Computational BioImaging

Original Research

Published on 14 Aug 2025

Stain-free artificial intelligence-assisted light microscopy for the identification of blood cells in microfluidic flow

in Computational BioImaging

Alexander Hunt
Holger Schulze
Kay Samuel
Robert B. Fisher
Till T. Bachmann

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1628724

589 views

Technology and Code

Accepted on 30 Jun 2025

An image analysis pipeline to quantify the spatial distribution of cell markers in stroma-rich tumors

in Computational BioImaging

Antoine A Ruzette
Nina Kozlova
Kayla A Cruz
Taru Muranen
Simon F Nørrelykke

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1619790

192 views

Original Research

Accepted on 27 Jun 2025

Novel Deep Learning for Multi-class Classification of Alzheimer's in Disability using MRI Datasets

in Computational BioImaging

Mohammad Ali Moni
Sumaiya Binte Shahid
Maleeha Kaikaus
Md. Hasanul Kabir
Mohammad Abu Yousuf
AKM Azad
A. S. Al-Moisheer
Naif Alotaibi
Dr. Salem A. Alyami
Touhid Bhuiyan

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1567219

482 views

Perspective

Published on 30 May 2025

Trail-blazing and keeping pace: building, retaining and expanding image analysis expertise

in Computational BioImaging

David Kirchenbuechler
Mariana De Niz
Constadina Arvanitis

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1613866

995 views

Original Research

Published on 17 Apr 2025

Classification of collagen remodeling in asthma using second-harmonic generation imaging, supervised machine learning and texture-based analysis

in Computational BioImaging

Natasha N. Kunchur
Joshua J. A. Poole
Jesse Levine
Tillie-Louise Hackett
Rebecca Thornhill
Leila B. Mostaço-Guidolin

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1539936

1,496 views

Brief Research Report

Published on 10 Mar 2025

Improving acne severity detection: a GAN framework with contour accentuation for image deblurring

in Computational BioImaging

Philomina Princiya Mascarenhas
M. S. Sannidhan
Ancilla J. Pinto
Dabis Camero
Jason Elroy Martis

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1485797

1,251 views

Brief Research Report

Published on 29 Jan 2025

End-to-end 3D instance segmentation of synthetic data and embryo microscopy images with a 3D Mask R-CNN

in Computational BioImaging

Gabriel David
Emmanuel Faure

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1497539

1,801 views
1 citation

Technology and Code

Published on 21 Oct 2024

Quantification of muscle fiber malformations using edge detection to investigate chronic muscle pressure ulcers

in Computational BioImaging

Charlene Z. L. Ong
N. Jannah M. Nasir
Roy E. Welsch
Lisa Tucker-Kellogg
Jagath C. Rajapakse

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1450146

1,404 views

Technology and Code

Published on 27 Sep 2024

SciJava Ops: an improved algorithms framework for Fiji and beyond

in Computational BioImaging

Gabriel J. Selzer
Curtis T. Rueden
Mark C. Hiner
Edward L. Evans
David Kolb
Marcel Wiedenmann
Christian Birkhold
Tim-Oliver Buchholz
Stefan Helfrich
Brian Northan

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1435733

2,821 views

Perspective

Published on 09 Feb 2024

A perspective on FAIR quality control in multiplexed imaging data processing

in Computational BioImaging

Wouter-Michiel A. M. Vierdag
Sinem K. Saka

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1336257

2,071 views
2 citations

Editorial

Published on 06 Feb 2024

Editorial: Phasor analysis for fluorescence lifetime data

in Computational BioImaging

Ruofan Cao
Yide Zhang
Jessica Houston

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1375480

1,481 views

Original Research

Published on 23 Jan 2024

Deep learning-based automated pipeline for blood vessel detection and distribution analysis in multiplexed prostate cancer images

in Computational BioImaging

Grigorios M. Karageorgos
Sanghee Cho
Elizabeth McDonough
Chrystal Chadwick
Soumya Ghose
Jonathan Owens
Kyeong Joo Jung
Raghu Machiraju
Robert West
James D. Brooks

Frontiers in Bioinformatics

doi 10.3389/fbinf.2023.1296667

3,077 views
4 citations

Original Research

Published on 22 Dec 2023

Improving fluorescence lifetime imaging microscopy phasor accuracy using convolutional neural networks

in Computational BioImaging

Varun Mannam
Jacob P. Brandt
Cody J. Smith
Xiaotong Yuan
Scott Howard

Frontiers in Bioinformatics

doi 10.3389/fbinf.2023.1335413

3,219 views
6 citations

Original Research

Published on 15 Dec 2023

Efficient semi-supervised semantic segmentation of electron microscopy cancer images with sparse annotations

in Computational BioImaging

Lucas Pagano
Guillaume Thibault
Walid Bousselham
Jessica L. Riesterer
Xubo Song
Joe W. Gray

Frontiers in Bioinformatics

doi 10.3389/fbinf.2023.1308707

1,878 views

Original Research

Published on 15 Dec 2023

Segmentation of cellular ultrastructures on sparsely labeled 3D electron microscopy images using deep learning

in Computational BioImaging

Archana Machireddy
Guillaume Thibault
Kevin G. Loftis
Kevin Stoltz
Cecilia E. Bueno
Hannah R. Smith
Jessica L. Riesterer
Joe W. Gray
Xubo Song

Frontiers in Bioinformatics

doi 10.3389/fbinf.2023.1308708

2,827 views
7 citations

Original Research

Published on 30 Nov 2023

Real-time open-source FLIM analysis

in Computational BioImaging

Kevin K. D. Tan
Mark A. Tsuchida
Jenu V. Chacko
Niklas A. Gahm
Kevin W. Eliceiri

Frontiers in Bioinformatics

doi 10.3389/fbinf.2023.1286983

4,386 views
7 citations