REVIEW article
Front. Cardiovasc. Med.
Sec. Atherosclerosis and Vascular Medicine
Summary of the best evidence for non-pharmacological interventions for dyslipidemia in patients with coronary heart disease
Zhi Zeng
Xin Zhou
Li Jiang
Yuan Huang
Xiaochun He
Huaili Luo
Mianyang Central Hospital, Mianyang, China
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Abstract
Objective: Retrieve, evaluate, and summarize evidence from domestic and international sources regarding non-pharmacological interventions for dyslipidemia in patients with coronary heart disease (CHD), providing reference for clinical practice. Methods: Following the "6S" evidence pyramid model, a systematic search was conducted for literature on 3 non-pharmacological interventions for dyslipidemia in CHD patients, both domestically and internationally, covering the period from January 2014 to December 2025. Two researchers independently screened and evaluated the studies for inclusion, after which the evidence was synthesized. Results: A total of 31 studies were ultimately included, comprising 15 English-language publications and 16 Chinese-language publications. Thirty-one evidence points were summarized, covering seven evidence themes: multidisciplinary team formation, assessment, lipid-lowering targets, lifestyle modification, non-pharmacological traditional Chinese medicine (TCM) interventions, health education, and follow-up management. Conclusion: This study provides a comprehensive summary of the best available evidence on non-pharmacological interventions for dyslipidemia in patients with CHD. The findings can serve as a valuable reference for clinical practitioners, enabling healthcare professionals to develop personalized intervention plans based on the lipid profiles and specific needs of CHD patients.
Summary
Keywords
Dyslipidemia, non-pharmacological interventions, patients with coronary heart disease, review, Summary of the evidence
Received
25 November 2025
Accepted
19 February 2026
Copyright
© 2026 Zeng, Zhou, Jiang, Huang, He and Luo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Xiaochun He; Huaili Luo
Disclaimer
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