REVIEW article
Front. Cell Dev. Biol.
Sec. Cancer Cell Biology
Volume 13 - 2025 | doi: 10.3389/fcell.2025.1572373
This article is part of the Research TopicProgress in Molecular Mechanisms and Targeted Therapies for Solid Tumor MicroenvironmentsView all 7 articles
The potential role of miR-155 in the tumorigenesis of cervical cancer
Provisionally accepted
- 1Department of Pathology, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China
- 2First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi Province, China
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Cervical cancer poses a major threat to the health of females and is the leading cause of mortality in females. Despite advancements in treatment, most cervical cancer patients have a poor prognosis due to late diagnosis and resistance to treatment. Investigating microRNAs introduces a new path for developing cancer prevention and treatment. miR-155, one of many microRNAs, plays an essential role in tumor development by regulating gene expression processes, such as transcription, translation, and splicing. In cervical cancer, a number of studies have been conducted to exploring the role and mechanisms of miR-155. Therefore, a comprehensive review summarizing all available findings is necessary to clarify the role of miR-155 in cervical cancer development and progression. This review presents an overview of the state-of-the-art research in miR-155 for cervical cancer, including cell apoptosis, migration, invasion, and drug resistance, and highlights its potential as a biomarker and therapeutic target for cervical cancer treatment and prognosis.
Keywords: cervical cancer, tumorigenesis, prognosis, Mechanism, clnical
Received: 07 Feb 2025; Accepted: 22 Jul 2025.
Copyright: © 2025 Chen, Zheng and Zeng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xianxu Zeng, Department of Pathology, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China
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