Frontiers in Cell and Developmental Biology | Molecular and Cellular Pathology

Original Research

Published on 30 May 2025

A machine learning model for predicting anatomical response to Anti-VEGF therapy in diabetic macular edema

in Molecular and Cellular Pathology

Wenrui Lu
Kunhong Xiao
Xuemei Zhang
Yuqing Wang
Wenbin Chen
Xierong Wang
Yunxi Ye
Yan Lou
Li Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1603958

511 views

Review

Published on 30 May 2025

Deep learning-driven approach for cataract management: towards precise identification and predictive analytics

in Molecular and Cellular Pathology

Shuaixin Lu
Lingling Ba
Jie Wang
Min Zhou
Peiyao Huang
Xiaohua Zhang
Simo Pan
Xinmiao Zhou
Kai Wen
Jing Sun

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1611216

704 views

Review

Accepted on 29 May 2025

Mitochondrial Metabolic Regulation of Macrophage Polarization in Osteomyelitis and Other Orthopedic Disorders: Mechanisms and Therapeutic Opportunities

in Molecular and Cellular Pathology

Jinglin Li
Lin Zhang
Jiaze Peng
Chuntao Zhao
Wenguang Li
Yang Yu
Xianpeng Huang
Fuyin Yang
Xuan Deng
Xuxu Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1604320

121 views

Review

Published on 29 May 2025

A comprehensive overview of focused ion beam-scanning electron microscopy (FIB-SEM) applications for the evaluation of outer retina

in Molecular and Cellular Pathology

Sanjay Ch
Rayne R. Lim
Shermaine W. Y. Low
Deana G. Grant
Sam Patterson
Aparna Ramasubramanian
Ashish K. Gadicherla
Shyam S. Chaurasia

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1586029

688 views

Editorial

Published on 29 May 2025

Editorial: Next generation micro-physiological systems for pragmatic use in regular industrial workflow

in Molecular and Cellular Pathology

Ali Kermanizadeh
David M. Brown
Wolfgang Moritz

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1607979

934 views

Brief Research Report

Accepted on 28 May 2025

POU5F1 bridges Hedgehog signalling and epithelial remodelling in COPD

in Molecular and Cellular Pathology

Laure M G Petit
Randa Belgacemi
Pauline Mulette
Audrey Brisebarre
Lynda SABER CHERIF
Maëva A Devilliers
Sarah Hatoum
Julien Ancel
Gonzague Delepine
ANNE DURLACH

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1566251

149 views

Review

Accepted on 28 May 2025

Single-Cell RNA Sequencing: New Insights for Pulmonary Endothelial Cells

in Molecular and Cellular Pathology

Ying Yang
Mengyuan Wang
Xiao Qiu
Rui Yang
Chengfang Yao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1576067

116 views

Original Research

Accepted on 26 May 2025

Revealing age-related changes in the intraocular microenvironment and senescence modulators based on aqueous humor proteomics via machine learning

in Molecular and Cellular Pathology

Sheng Xiao Huang
Tiansheng Chou
Xinhua Liu
Kun Zeng
Liangnan Sun
Zonghui Yan
Shaoyi Mei
Wenqun Xi
Zongyi Zhan
Yi Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1583330

159 views

Original Research

Published on 26 May 2025

Early detection of retinal and choroidal microvascular impairments in diabetic patients with myopia

in Molecular and Cellular Pathology

Yufei Wu
Jiahui Jiang
Xiaoyu Deng
Xixi Zhang
Jinger Lu
Zian Xu
Yitian Zhao
Zai-Long Chi
Qinkang Lu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1609928

487 views

Review

Accepted on 23 May 2025

Large language models in the management of chronic ocular diseases： A scoping review

in Molecular and Cellular Pathology

Ting Fan
Jia-tong Zhang
Xiao-Xi Song
Bo-cheng Tian
Ming-Ke Tian
Zhi-chang Zhang
Jing Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608988

165 views

Original Research

Published on 23 May 2025

Large language model-based multimodal system for detecting and grading ocular surface diseases from smartphone images

in Molecular and Cellular Pathology

Zhongwen Li
Zhouqian Wang
Liheng Xiu
Pengyao Zhang
Wenfang Wang
Yangyang Wang
Gang Chen
Weihua Yang
Wei Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1600202

593 views

Original Research

Published on 22 May 2025

snRNA-seq reveals subcutaneous white adipose tissue remodeling upon return to thermoneutrality after cold stimulation

in Molecular and Cellular Pathology

Yusha Yang
Guanyu Zhang
Ting Yi
Shuran Yang
Shuai Wu
Yongqiang Zhang
Li Zhang
Xi Li
Xiuxuan Wu
Jun Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1578180

860 views

Original Research

Published on 22 May 2025

Machine learning-driven prediction of cycloplegic refractive error in Chinese children

in Molecular and Cellular Pathology

Bichi Chen
Li Tian
Fuyue Tian
Qiaochu Yang
Ying Ruan
Ying Li
Min Cao
Chuanyan Wu
Maoyuan Yang
Suzhong Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608494

546 views

Original Research

Published on 22 May 2025

Cell-based high-content approach for SARS-CoV-2 neutralization identifies unique monoclonal antibodies and PI3K pathway inhibitors

in Molecular and Cellular Pathology

Carly R. Cabel
Briana A. Guzman
Elaheh Alizadeh
Shuaizhi Li
Cameron Holberg
Chonlarat Wichaidit
Darren A. Cusanovich
Andrew L. Paek
Gregory R. J. Thatcher
Koenraad Van Doorslaer

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1538934

729 views

Original Research

Published on 22 May 2025

Integration of machine learning and bulk sequencing revealed exosome-related gene FOSB was involved in the progression of abdominal aortic aneurysm

in Molecular and Cellular Pathology

Xianlu Ma
Hongjie Zhou
Ren Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1554972

405 views

Original Research

Published on 21 May 2025

Based on TransRes-Pix2Pix network to generate the OBL image during SMILE surgery

in Molecular and Cellular Pathology

Zeyu Zhu
Peifen Lin
Lingling Zhong
Qing Wang
Jingjing Xu
Kang Yu
Zheliang Guo
Yicheng Xu
Taorong Qiu
Yifeng Yu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1598475

598 views