Frontiers in Cell and Developmental Biology

Original Research

Published on 17 Jul 2026

CNOT11 depletion is associated with autophagy-related responses and IL-6–JAK–STAT signaling in cancer cells

in Signaling

Saori Nishijima
Toru Suzuki
Tadashi Yamamoto

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1854333

309 views

Review

Accepted on 13 Jul 2026

The emerging metabolic role and treatment target of CPT1A in CRC

in Signaling

Xinyu Zhu
Jintao Yuan
Fei Mao
Tao Jin
Chengxue Yi

Frontiers in Cell and Developmental Biology

Mini Review

Accepted on 10 Jul 2026

Beyond KIR and NKG2A Blockade: Reprogramming NK-Cell Immunity in Solid Tumors

in Signaling

Claudia Pastorino
Michela Falco
Chiara Giordano
Najmeh Zarefeizabadi
Mariangela Rutigliani
Alessio Carbone
Matteo Clavarezza
Fulvia Ortolani
Luca Nanni
Mariella Della Chiesa

Frontiers in Cell and Developmental Biology

135 views

Original Research

Accepted on 06 Jul 2026

Toll/IL-1 receptor domain-containing adaptor protein plays a crucial role in macrophage-mediated hepatic stellate cell activation in alcoholic liver disease

in Signaling

Mirza S Baig
Pramod Patidar
Alexander G. Obukhov
Luciano Saso

Frontiers in Cell and Developmental Biology

127 views

Review

Published on 06 Jul 2026

The primary cilium as a compartmentalized signaling hub in tissue immunity and homeostasis

in Signaling

Anqi Zhang
Changjun Huo
Ting Song

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1875556

553 views

Mini Review

Published on 03 Jul 2026

From metabolism to genome integrity: NRF2 as a key mediator of cancer therapy response

in Signaling

Andrea Sarrecchia
Claudia Di Girolamo
Irene Taddei
Claudia Contadini
Daniela Barilà
Claudia Cirotti

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1868571

477 views

Original Research

Accepted on 01 Jul 2026

Conditional deletion of Wnt5a in myeloid osteoclast precursors results in low bone mass via disruption of osteoblast migration and focal adhesion dynamics

in Signaling

Valentina Daponte
Chandra Gavva
David Justin Kapfhamer
Joseph Roberts
Katrin Henke
Hicham Drissi

Frontiers in Cell and Developmental Biology

222 views

Review

Published on 01 Jul 2026

Microenvironmental remodeling in FLASH radiotherapy

in Signaling

Yubo Zhao
Hang Li
Jiaqiao Zhong
Jianguo Xu
Liangxue Zhou
Yi Liu
Yuelong Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1883109

663 views

Review

Published on 01 Jul 2026

Advances in drug addiction research using Caenorhabditis elegans: behavioral and molecular mechanisms

in Signaling

Lihua Yang
Shuang Wu
Jiale Liu
Wenjun Wang
Qinhong Yin
Elizabeth Rosalind Thomas
Xiang Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1880079

458 views

Review

Published on 30 Jun 2026

Endothelial-to-mesenchymal transition in atherosclerosis: mechanisms, therapeutic targets, and future perspectives

in Signaling

Xiaoshan Cui
Yuanyuan Chen
Hailang Luo
Hongzheng Li
Zikai Yu
Hao Guo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1850232

592 views

Original Research

Published on 30 Jun 2026

Association of triglyceride glucose index and volumetric bone mineral density in T2DM: fat distribution as a potential indirect link

in Signaling

Bei Huang
Feng Xu
Jun-Jie Yang
Peng-Xin Wang
Zi-Fei Liu
Feng-Rong Liu
Hai-Yang Li
Ling-Qing Yuan
Jun Liu
Xiao Lin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1811476

537 views

Review

Published on 30 Jun 2026

Decoding the secretory blueprint of bone healing: from gradients to regeneration

in Signaling

Wenxiao Yang
Yuanfang Wang
Keda Liu
Yutong Zhao
Wei Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1873387

531 views

Review

Accepted on 29 Jun 2026

The molecular mechanisms of gas signaling molecules in bronchopulmonary dysplasia related lung injury

in Signaling

Lulu Zhang
Lanbo Hu
Fangrui Ding

Frontiers in Cell and Developmental Biology

146 views

Review

Published on 26 Jun 2026

MicroRNA-mediated regulation of hair follicle regeneration: mechanisms, delivery strategies, and translational perspectives

in Signaling

Yuyu Deng
Kechun Hong
Mengting Xiong
Changxia Li
Xiaohua Tao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1880276

746 views

Original Research

Published on 23 Jun 2026

Sesamin attenuates atherosclerosis by alleviating vascular endothelial ferroptosis-related injury via m6A-dependent regulation of SREBF1 expression

in Signaling

Xiaoying Chen
Guanyi Zheng
Kailong Fu
Minglong Yao
Kan Lin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1807359

699 views

Review

Accepted on 22 Jun 2026

Decoding the Molecular Mechanisms of Pyroptosis and Its Therapeutic Development Prospects

in Signaling

Yi Shen
Qiangqiang Zheng
Yang Yuan
wei Chen
Min Liang
Feng Jian
Maohua Li
Yunfeng Zhou

Frontiers in Cell and Developmental Biology

240 views

Mini Review

Accepted on 18 Jun 2026

Targeting Glycolytic Pathways to Overcome Chemoresistance in the Tumor Microenvironment: Mechanistic Insights and Emerging Therapeutics

in Signaling

Zhongyi Tan
Lai Wen
Hewen Guan
Bao Nabuqi
Zijing Wu
Xu Ji
Lin Lin

Frontiers in Cell and Developmental Biology

265 views

Review

Published on 17 Jun 2026

Decoding signaling crosstalk in pulpitis: pathogenesis and precision therapeutics

in Signaling

Zhaohui Jia
Zongzong Sun
Hairui Zhou

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1872666

733 views

Review

Published on 17 Jun 2026

H2S-mediated protein S-sulfhydration: a novel regulatory module in lipid metabolism

in Signaling

Mingchang Pang
Haoyang Chen
Shuofeng Li
Huayu Yang
Yilei Mao
Yongfa Huang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1866744

751 views

Original Research

Published on 12 Jun 2026

Connective tissue profiling in keratinized and non-keratinized oral mucosa reveals distinct extracellular and intracellular features

in Signaling

Ruoxuan Huang
Leyao Xu
Chunhsin Hsu
Yuanxiang Liu
Runheng Liu
Shudan Deng
Zhipeng Li
Zetao Chen
Shoucheng Chen
Zhuofan Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1815527

1,008 views

Original Research

Published on 05 Jun 2026

Broccoli-derived nanovesicles protect against UVB-induced skin photoaging via integrated transcriptomic and proteomic reprogramming of redox and extracellular matrix homeostasis

in Signaling

Kunjie Li
Songfa Lin
Yanwei Xiao
Pengjun Zhou
Niu Xiang
Bo Cheng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1806671

1,028 views

Original Research

Published on 04 Jun 2026

FGFR inhibitor resistance in cervical cancer: a role for integrin α2 and mTOR signalling

in Signaling

Nauf Bou Antoun
Richard P. Grose
Anthony J. Walker
Helmout Modjtahedi
Athina Myrto Chioni

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1863679

2,566 views

Original Research

Published on 03 Jun 2026

Mitofusins are required for specialized mitochondrial morphology and function of rod photoreceptor cells

in Signaling

Michael Landowski
Ryo Hagimori
Purnima Gogoi
Pawan K. Shahi
Kazuya Oikawa
Vijesh J. Bhute
Gillian J. McLellan
Sakae Ikeda
Ken-ichi Yamada
Bikash R. Pattnaik

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1724328

1,658 views
1 citation

Review

Published on 01 Jun 2026

G protein-coupled receptor signaling in osteogenic bone mesenchymal stem/stromal cells

in Signaling

Trevor J. Wolfe
Samantha R. Weaver

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1795445

1,450 views

1,339 articles

articles

CNOT11 depletion is associated with autophagy-related responses and IL-6–JAK–STAT signaling in cancer cells

The emerging metabolic role and treatment target of CPT1A in CRC

Beyond KIR and NKG2A Blockade: Reprogramming NK-Cell Immunity in Solid Tumors

Toll/IL-1 receptor domain-containing adaptor protein plays a crucial role in macrophage-mediated hepatic stellate cell activation in alcoholic liver disease

The primary cilium as a compartmentalized signaling hub in tissue immunity and homeostasis

From metabolism to genome integrity: NRF2 as a key mediator of cancer therapy response

Conditional deletion of Wnt5a in myeloid osteoclast precursors results in low bone mass via disruption of osteoblast migration and focal adhesion dynamics

Microenvironmental remodeling in FLASH radiotherapy

Advances in drug addiction research using Caenorhabditis elegans: behavioral and molecular mechanisms

Endothelial-to-mesenchymal transition in atherosclerosis: mechanisms, therapeutic targets, and future perspectives

Association of triglyceride glucose index and volumetric bone mineral density in T2DM: fat distribution as a potential indirect link

Decoding the secretory blueprint of bone healing: from gradients to regeneration

The molecular mechanisms of gas signaling molecules in bronchopulmonary dysplasia related lung injury

MicroRNA-mediated regulation of hair follicle regeneration: mechanisms, delivery strategies, and translational perspectives

Sesamin attenuates atherosclerosis by alleviating vascular endothelial ferroptosis-related injury via m6A-dependent regulation of SREBF1 expression

Decoding the Molecular Mechanisms of Pyroptosis and Its Therapeutic Development Prospects

Targeting Glycolytic Pathways to Overcome Chemoresistance in the Tumor Microenvironment: Mechanistic Insights and Emerging Therapeutics

Decoding signaling crosstalk in pulpitis: pathogenesis and precision therapeutics

H2S-mediated protein S-sulfhydration: a novel regulatory module in lipid metabolism

Connective tissue profiling in keratinized and non-keratinized oral mucosa reveals distinct extracellular and intracellular features

Broccoli-derived nanovesicles protect against UVB-induced skin photoaging via integrated transcriptomic and proteomic reprogramming of redox and extracellular matrix homeostasis

FGFR inhibitor resistance in cervical cancer: a role for integrin α2 and mTOR signalling

Mitofusins are required for specialized mitochondrial morphology and function of rod photoreceptor cells

G protein-coupled receptor signaling in osteogenic bone mesenchymal stem/stromal cells