Frontiers in Cell and Developmental Biology

Original Research

Accepted on 13 Feb 2026

Efficacy and Safety of Autologous Cell-Based Therapies for Atrophic Acne Scar Treatment: An Updated Systematic Review and Meta-Analysis with In-Depth Methodological and Clinical Insights

in Stem Cell Research

Shuang Zhang
Yanxia Ren
Xudong Hong
Yuanzhe Shi
Tingting Si
Xudong Zhang

Frontiers in Cell and Developmental Biology

Original Research

Accepted on 13 Feb 2026

A conserved bioelectrical signature defines subventricular zone-derived human fetal neural stem cells and tracks their differentiation state

in Stem Cell Research

Roberta De Zio
Diletta Lucia Capobianco
Daniela Celeste Profico
Giada D'Aloisio
Giuseppe Procino
Maurizio Gelati
Angelo Luigi Vescovi
Francesco Pisani
Maria Svelto
Andrea Gerbino

Frontiers in Cell and Developmental Biology

Review

Published on 12 Feb 2026

Human cranial stem cells: developmental, pathologic, and therapeutic implications

in Stem Cell Research

Anvith Reddy
Anna Means
Sarah Qaddo
Victoria Tong
Franklin Gergoudis
Noah Alter
Ricardo Torres-Guzman
Michael Golinko
Wesley Thayer
Izabela Galdyn

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1718526

405 views

Review

Published on 11 Feb 2026

A novel paradigm for chronic subdural hematoma: regenerative medicine strategies targeting the pathological microenvironment

in Stem Cell Research

Zhijian Xu
Song Yang
Guifang Zheng
Huahui Chen
Xing Wan
Hu Xu
Yutiao Xu
Jian Wang
Minfeng Tong
Qi Tu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1757623

327 views

Editorial

Published on 10 Feb 2026

Editorial: Novel insights into cellular mechanisms and therapies for tissue regeneration

in Stem Cell Research

Weiqiang Lan
Yuheng Liu
Zhangheng Huang
Chuan Guo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1796515

247 views

Review

Accepted on 09 Feb 2026

Mechanical Forces Orchestrate the Epigenetic Landscape of Oral Mesenchymal Stem/Progenitor Cell Fate in Dental and Periodontal Tissues

in Stem Cell Research

Yikun Zhou
Gengming Zhang
Hong He

Frontiers in Cell and Developmental Biology

Review

Accepted on 09 Feb 2026

Ethical Review Key Considerations for Organoid Applications in Biomedical Research-a systematic review

in Stem Cell Research

Guo Zhili

Frontiers in Cell and Developmental Biology

Review

Accepted on 06 Feb 2026

The therapeutic potential of bone marrow mesenchymal stem cells-derived exosomes for retinal and optic nerve disease

in Stem Cell Research

Mingzhe Shi
Shounan Qi
Feifan Qi
Chenguang Wang

Frontiers in Cell and Developmental Biology

119 views

Correction

Published on 06 Feb 2026

Correction: A comparative analysis of stem cells derived from young rabbit knee joints: the potentially superior performance of decellularized extracellular matrix pretreated infrapatellar fat pad stem cells on nanofiber scaffolds

in Stem Cell Research

Zhixin Wei
Qingqing Yu
Qingyun Xie
Dongfa Liao
Xue Gou
Song Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1779159

283 views

Original Research

Published on 06 Feb 2026

Bioinspired artificial nanovesicles engineered from 3D spheroid-cultured UC-MSCs enhance angiogenic activity in vitro: functional proof-of-concept for ischemic applications

in Stem Cell Research

Prakash Gangadaran
Ramya Lakshmi Rajendran
Ji Min Oh
Jaeyoung Son
Chae Moon Hong
Byeong-Cheol Ahn

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1695559

418 views

Original Research

Published on 05 Feb 2026

Stem cell therapy targets THBS1 to reverse endometrial fibrosis

in Stem Cell Research

Xiaochuan Yu
Lijuan Shi
MingBo Qu
Yonggang Zhang
Yating Zhang
Xinyu Xu
Lina Liu
Huanan Wang
Huali Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1766915

486 views

Original Research

Published on 04 Feb 2026

Global clinical trial landscape of stem cell-based therapies for osteoarthritis: trends and translational implications

in Stem Cell Research

Xin Li
Yue Zhao
Dongsheng Guo
Chen Yan
Jian Zhang
Lin Cheng
Yuefu Dong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1757935

745 views

Original Research

Accepted on 02 Feb 2026

Extracellular Vesicles Modulate Skin Aging Biomarkers in 3D Reconstructed Full-Thickness Skin Model

in Stem Cell Research

YAO TENG
Elias BOU SAMRA
Sarah GIRARDEAU-HUBERT
Richard BETTS
Franck JUCHAUX
Xavier MARAT
Benedicte FALLOU
Lingyan ZHONG
Rodrigo De Vecchi
Nan HUANG

Frontiers in Cell and Developmental Biology

150 views

Review

Published on 02 Feb 2026

Deer antler stem cell-derived exosomes: a regenerative medicine powerhouse from nature’s own repair kit

in Stem Cell Research

Xidong Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1672234

774 views

Original Research

Accepted on 30 Jan 2026

Dynamic Activation and Dual Roles of SOX9⁺ Hepatocytes in Liver Regeneration under acute and chronic injuryand Chronic Disease Revealed by Single-Cell Transcriptomics

in Stem Cell Research

Junwei Zhang
Yiyao Xu
Xin Lu

Frontiers in Cell and Developmental Biology

152 views

Review

Published on 30 Jan 2026

Cellular plasticity: a double-edged sword driving malignant transformation and adaptive remodeling in stem cells

in Stem Cell Research

Xue Du
Zhimei Lin
Yijun Zeng
Chunbao Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1752590

577 views

Original Research

Accepted on 29 Jan 2026

Ascorbic Acid enhances in vitro Primordial germ cell-like cell differentiation from mouse ESCs

in Stem Cell Research

Umesh Kumar
Nithyapriya Kumar
P Chandra Shekar
Kumarasamy Thangaraj

Frontiers in Cell and Developmental Biology

354 views

Review

Published on 28 Jan 2026

Therapeutic value of mesenchymal stem cell-derived extracellular vesicles in hypertrophic and keloid scars: a systematic review and meta-analysis

in Stem Cell Research

Tianhui Zhai
Wanqi Tang
Pengchao Liu
Yakun Liang
Zhihong Ma
Leiqiang Fan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1739106

759 views

Original Research

Accepted on 27 Jan 2026

CG-RecNet: A Gated and Attention-Fused Deep Learning Framework for Label-Free and Classification of Neural Stem Cell Differentiation via Imaging Flow Cytometry

in Stem Cell Research

Qinzi Li
Fang Liu
JunYu Zhou
XuanJian Zou
ChenLin Gao
JingZe Li

Frontiers in Cell and Developmental Biology

184 views

Hypothesis and Theory

Published on 27 Jan 2026

Altered senescence and mitochondrial transcriptome defines age-related changes in satellite cells

in Stem Cell Research

Fasih A. Rahman
Joe Quadrilatero

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1699206

930 views

Original Research

Accepted on 26 Jan 2026

AI and Big Data driven knowledge mapping of exosome–hydrogel research in orthopedic regeneration and tissue engineering

in Stem Cell Research

Qinghan Li
Liming Lou
Shuaishuai Wang
Minglei Zhang

Frontiers in Cell and Developmental Biology

181 views

Original Research

Published on 23 Jan 2026

BMP and NODAL paracrine signalling regulate the totipotent-like cell state in embryonic stem cells

in Stem Cell Research

Sanidhya Jagdish
Loick Joumier
Sabin Dhakal
Gilberto Duran-Bishop
Mohammed Usama
Mohan Malleshaiah

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1720355

725 views

Review

Published on 23 Jan 2026

Beyond the canonical niche: how astrocytes carried neurogenic potential into the brain parenchyma

in Stem Cell Research

Marco Fogli
Giulia Nato
Paolo Peretto
Annalisa Buffo
Federico Luzzati

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1737065

783 views

Original Research

Published on 22 Jan 2026

Menstrual blood-derived mesenchymal stromal cell secretome modulates macrophage polarization in a preconditioning-dependent manner

in Stem Cell Research

María Ángeles de Pedro
María Pulido
Ana María Marchena
Verónica Álvarez
Francisco Manuel González-Nuño
Witold Szymański
Johanna Pörschke
Silke Reinartz
Johannes Graumann
Elke Pogge von Strandmann

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1691010

694 views

1,784 articles

articles

Efficacy and Safety of Autologous Cell-Based Therapies for Atrophic Acne Scar Treatment: An Updated Systematic Review and Meta-Analysis with In-Depth Methodological and Clinical Insights

A conserved bioelectrical signature defines subventricular zone-derived human fetal neural stem cells and tracks their differentiation state

Human cranial stem cells: developmental, pathologic, and therapeutic implications

A novel paradigm for chronic subdural hematoma: regenerative medicine strategies targeting the pathological microenvironment

Editorial: Novel insights into cellular mechanisms and therapies for tissue regeneration

Mechanical Forces Orchestrate the Epigenetic Landscape of Oral Mesenchymal Stem/Progenitor Cell Fate in Dental and Periodontal Tissues

Ethical Review Key Considerations for Organoid Applications in Biomedical Research-a systematic review

The therapeutic potential of bone marrow mesenchymal stem cells-derived exosomes for retinal and optic nerve disease

Correction: A comparative analysis of stem cells derived from young rabbit knee joints: the potentially superior performance of decellularized extracellular matrix pretreated infrapatellar fat pad stem cells on nanofiber scaffolds

Bioinspired artificial nanovesicles engineered from 3D spheroid-cultured UC-MSCs enhance angiogenic activity in vitro: functional proof-of-concept for ischemic applications

Stem cell therapy targets THBS1 to reverse endometrial fibrosis

Global clinical trial landscape of stem cell-based therapies for osteoarthritis: trends and translational implications

Extracellular Vesicles Modulate Skin Aging Biomarkers in 3D Reconstructed Full-Thickness Skin Model

Deer antler stem cell-derived exosomes: a regenerative medicine powerhouse from nature’s own repair kit

Dynamic Activation and Dual Roles of SOX9⁺ Hepatocytes in Liver Regeneration under acute and chronic injuryand Chronic Disease Revealed by Single-Cell Transcriptomics

Cellular plasticity: a double-edged sword driving malignant transformation and adaptive remodeling in stem cells

Ascorbic Acid enhances in vitro Primordial germ cell-like cell differentiation from mouse ESCs

Therapeutic value of mesenchymal stem cell-derived extracellular vesicles in hypertrophic and keloid scars: a systematic review and meta-analysis

CG-RecNet: A Gated and Attention-Fused Deep Learning Framework for Label-Free and Classification of Neural Stem Cell Differentiation via Imaging Flow Cytometry

Altered senescence and mitochondrial transcriptome defines age-related changes in satellite cells

AI and Big Data driven knowledge mapping of exosome–hydrogel research in orthopedic regeneration and tissue engineering

BMP and NODAL paracrine signalling regulate the totipotent-like cell state in embryonic stem cells

Beyond the canonical niche: how astrocytes carried neurogenic potential into the brain parenchyma

Menstrual blood-derived mesenchymal stromal cell secretome modulates macrophage polarization in a preconditioning-dependent manner