Frontiers in Cell and Developmental Biology

Original Research

Published on 06 May 2025

Generation and functional characterization of tuft cells in non-human primate pancreatic ducts through organoid culture systems

in Stem Cell Research

Kosuke Sakaguchi
Chiemi Kimura-Nakajima
Akihiko Inaba
Yoshiko Hatano
Hanako Ogawa
Yuichi Koshiishi
Keisuke Tanaka
Tatsuya Kometani
Makoto Ohmoto
Koji Sato

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1593226

4,910 views
1 citation

Brief Research Report

Published on 30 Apr 2025

Using a brain-like endothelial cell differentiation to characterize the CS79iBRCA-n2 BRCA1 mutated patient derived stem cell line

in Stem Cell Research

Natalie G. Alexander
Kylie A. Buchanan
Alexandra E. Meyer
Lauren M. Mitterway
Caroline O. Vanderburgh
Shreyas S. Rao
Brandon J. Kim

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1516669

2,680 views

Review

Published on 30 Apr 2025

Challenges of in vitro modelling of liver fibrosis

in Stem Cell Research

Patricia Ros-Tarraga
Estela Villanueva-Badenas
Estela Sanchez-Gonzalez
Gloria Gallego-Ferrer
M. Teresa Donato
Laia Tolosa

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1567916

4,961 views
3 citations

Original Research

Published on 29 Apr 2025

Dominant RDH12-retinitis pigmentosa impairs photoreceptor development and implicates cone involvement in retinal organoids

in Stem Cell Research

Cécile Méjécase
Ya Zhou
Nicholas Owen
Pablo Soro-Barrio
Riccardo Cheloni
Neelima Nair
Hajrah Sarkar
Lyes Toualbi
Mariya Moosajee

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1511066

3,699 views
2 citations

Original Research

Published on 29 Apr 2025

Mitochondria-derived reactive oxygen species induce over-differentiation of neural stem/progenitor cells after non-cytotoxic cisplatin exposure

in Stem Cell Research

Felipe A. Bustamante-Barrientos
Eliana Lara-Barba
Yeimi Herrera-Luna
Cynthia García-Guerrero
Eduardo Silva-Pavez
Jonathan Morales-Reyes
María Jesús Araya
Liliana Yanten-Fuentes
Noymar Luque-Campos
Claudia Altamirano

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1555153

4,137 views
5 citations

Original Research

Published on 24 Apr 2025

TAL1 overexpression in induced pluripotent stem cells promotes the formation of hematopoietic cell-forming complexes but inhibits enucleation in vitro

in Stem Cell Research

Arim Shin
Sung Ah Park
Ji Yeon Kim
Eun Jung Baek

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1474631

2,837 views
2 citations

Original Research

Published on 23 Apr 2025

Dapagliflozin ameliorates intestinal stem cell aging by regulating the MAPK signaling pathway in Drosophila

in Stem Cell Research

Jinhua Yan
Chenxi Feng
Hanmei Zhang
Ting Luo
Haiyang Chen
Haiou Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1576258

3,767 views

Review

Published on 22 Apr 2025

The role of endothelial cells in pancreatic islet development, transplantation and culture

in Stem Cell Research

Ajun Geng
Shubo Yuan
Qing Cissy Yu
Yi Arial Zeng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1558137

5,152 views
2 citations

Original Research

Published on 08 Apr 2025

Engineered mesenchymal stromal cells with interleukin-1beta sticky-trap attenuate osteoarthritis in knee joints

in Stem Cell Research

Christopher Kim
Biao Li
Sayaka Nakamura
Eric J. Neely
Jason S. Rockel
Tatiana Oussenko
Puzheng Zhang
Mohit Kapoor
Andras Nagy

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1559155

3,279 views
2 citations

Original Research

Published on 04 Apr 2025

GSDME knockout alleviates hematopoietic stem cell irradiation injury and aggravates myeloid-biased differentiation

in Stem Cell Research

Lulu Su
Yinping Dong
Bowen Guan
Yuquan Wang
Yanhua Lu
Xinyue Wang
Wenxuan Li
Qidong Huo
Aimin Meng
Deguan Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1544320

2,644 views

Review

Published on 31 Mar 2025

Application of human cardiac organoids in cardiovascular disease research

in Stem Cell Research

Hongyan Zhang
Peng Qu
Jun Liu
Panke Cheng
Qian Lei

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1564889

6,500 views
3 citations

Review

Published on 27 Mar 2025

Mesenchymal stromal/stem cell-derived exosomes as a potential therapeutic approach to osteoarthritis combined with type 2 diabetes mellitus

in Stem Cell Research

Siyi Xie
Meiling Liu
Yajie Kong
Yiming Yang
Ruixue Chen
Yuzhong Wang
Shuxing Cao
Yongzhou Song

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1549096

4,983 views
2 citations

Original Research

Published on 26 Mar 2025

A comparative analysis of stem cells derived from young rabbit knee joints: the potentially superior performance of decellularized extracellular matrix pretreated infrapatellar fat pad stem cells on nanofiber scaffolds

in Stem Cell Research

Zhixin Wei
Qingqing Yu
Qingyun Xie
Dongfa Liao
Xue Gou
Song Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1539308

2,468 views

Original Research

Published on 26 Mar 2025

Ca2+/calmodulin-dependent protein kinase II regulates the inflammatory hDPSCs dentino-differentiation via BDNF/TrkB receptor signaling

in Stem Cell Research

Ji Hyun Kim
Muhammad Irfan
Sreelekshmi Sreekumar
Kerwin Chong
Jin Hong
Satish Alapati
Seung Chung

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1558736

2,120 views
4 citations

Original Research

Published on 26 Mar 2025

Identification of disease-stage therapeutic responses of mesenchymal stromal cells retrieved from murine osteoarthritic joints

in Stem Cell Research

Ana Ivanovska
Patrizio Mancuso
Amy Burke
Conor Hennessy
Swarna Raman
Claire Dooley
Steven McLoughlin
Georgina Shaw
Eka Mukeria
Jamie Reilly

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1521437

3,074 views
1 citation

Hypothesis and Theory

Published on 24 Mar 2025

Mesangiogenic progenitor cells: a mesengenic and vasculogenic branch of hemopoiesis? A story of neglected plasticity

in Stem Cell Research

Simone Pacini

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1513440

1,231 views

Methods

Published on 21 Mar 2025

Comparison between manual and automated methods for the isolation of mononuclear cells and mesenchymal stem cells using ficoll: efficacy and reproducibility

in Stem Cell Research

Ester Moñivas
Concepción Aguayo
Silvia de la Calle
Paula Martínez
Nieves Repollés
Mercedes Zurita

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1556697

2,500 views
1 citation

Original Research

Published on 19 Mar 2025

Generation and characterization of induced pluripotent stem cells of small apes

in Stem Cell Research

Yusuke Hamazaki
Hiroto Akuta
Hikaru Suzuki
Hideyuki Tanabe
Kenji Ichiyanagi
Takuya Imamura
Masanori Imamura

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1536947

3,909 views
2 citations

Editorial

Published on 17 Mar 2025

Editorial: Functional implications of Piwi proteins and piRNAs in stem cell maintenance and development

in Stem Cell Research

Fernanda Loureiro Almeida O’Sullivan
Ani V. Das
Patricia Rojas-Ríos

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1583955

1,612 views

Original Research

Published on 17 Mar 2025

Bibliometric and visualized analysis of the applications of exosomes for bone regeneration

in Stem Cell Research

Shuai Ai
Zhou Xie
Ningdao Li
Runhan Zhao
Xiao Qu
Haining Zhou
Dagang Tang
Jun Zhang
Xiaoji Luo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1552727

3,027 views
2 citations

Correction

Published on 13 Mar 2025

Corrigendum: Advances in application of hypoxia-preconditioned mesenchymal stem cell-derived exosomes

in Stem Cell Research

Haitao Zhuo
Yunfei Chen
Guifang Zhao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1583347

1,267 views

Original Research

Published on 13 Mar 2025

Unraveling the impact of human cerebrospinal fluid on human neural stem cell fate

in Stem Cell Research

Klaudia Radoszkiewicz
Aleksandra Bzinkowska
Monika Sypecka
Dorota Sulejczak
Daniela Ferrari
Maurizio Gelati
Angelo Luigi Vescovi
Anna Sarnowska

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1527557

2,475 views
1 citation

Original Research

Published on 12 Mar 2025

Cerebrospinal fluid-contacting neurons: a promising source for adult neural stem cell transplantation in spinal cord injury treatment

in Stem Cell Research

Zhangrong Luo
Zeyu Shangguan
Liang Cao
Yi Zhang
Qizhe Li
Xuexing Shi
Jiangquan Fu
Chunqing Wang
Xiaowei Dou
Wei Tan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1549194

3,093 views
2 citations

Review

Published on 12 Mar 2025

Regulation of HSC development and function by Lin28b

in Stem Cell Research

Grant Cox
Michihiro Kobayashi
Brian D. Rudd
Momoko Yoshimoto

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1555877

3,817 views
2 citations

1,782 articles

articles

Generation and functional characterization of tuft cells in non-human primate pancreatic ducts through organoid culture systems

Using a brain-like endothelial cell differentiation to characterize the CS79iBRCA-n2 BRCA1 mutated patient derived stem cell line

Challenges of in vitro modelling of liver fibrosis

Dominant RDH12-retinitis pigmentosa impairs photoreceptor development and implicates cone involvement in retinal organoids

Mitochondria-derived reactive oxygen species induce over-differentiation of neural stem/progenitor cells after non-cytotoxic cisplatin exposure

TAL1 overexpression in induced pluripotent stem cells promotes the formation of hematopoietic cell-forming complexes but inhibits enucleation in vitro

Dapagliflozin ameliorates intestinal stem cell aging by regulating the MAPK signaling pathway in Drosophila

The role of endothelial cells in pancreatic islet development, transplantation and culture

Engineered mesenchymal stromal cells with interleukin-1beta sticky-trap attenuate osteoarthritis in knee joints

GSDME knockout alleviates hematopoietic stem cell irradiation injury and aggravates myeloid-biased differentiation

Application of human cardiac organoids in cardiovascular disease research

Mesenchymal stromal/stem cell-derived exosomes as a potential therapeutic approach to osteoarthritis combined with type 2 diabetes mellitus

A comparative analysis of stem cells derived from young rabbit knee joints: the potentially superior performance of decellularized extracellular matrix pretreated infrapatellar fat pad stem cells on nanofiber scaffolds

Ca2+/calmodulin-dependent protein kinase II regulates the inflammatory hDPSCs dentino-differentiation via BDNF/TrkB receptor signaling

Identification of disease-stage therapeutic responses of mesenchymal stromal cells retrieved from murine osteoarthritic joints

Mesangiogenic progenitor cells: a mesengenic and vasculogenic branch of hemopoiesis? A story of neglected plasticity

Comparison between manual and automated methods for the isolation of mononuclear cells and mesenchymal stem cells using ficoll: efficacy and reproducibility

Generation and characterization of induced pluripotent stem cells of small apes

Editorial: Functional implications of Piwi proteins and piRNAs in stem cell maintenance and development

Bibliometric and visualized analysis of the applications of exosomes for bone regeneration

Corrigendum: Advances in application of hypoxia-preconditioned mesenchymal stem cell-derived exosomes

Unraveling the impact of human cerebrospinal fluid on human neural stem cell fate

Cerebrospinal fluid-contacting neurons: a promising source for adult neural stem cell transplantation in spinal cord injury treatment

Regulation of HSC development and function by Lin28b