MINI REVIEW article
Front. Cell. Infect. Microbiol.
Sec. Microbes and Innate Immunity
Volume 15 - 2025 | doi: 10.3389/fcimb.2025.1547525
This article is part of the Research TopicCurrent molecular, immunological, pathological and clinical aspects of pathogenic infectionsView all 11 articles
Exosome in HBV infection: current concepts and future perspectives
Provisionally accepted
- Fengdu General Hospital, Chongqin, China
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Exosomes are nanoparticles delimited by a lipid bilayer that are secreted by a wide variety of cells. They play a significant role in the pathophysiological processes associated with HBV infection, which poses huge burdens for public health. Emerging evidence has been demonstrated that exosomes are extensively associated with the replication and transmission processes of HBV. In this review, we outline the process of exosome production, composition and function. Moreover, we elaborate on the essential role of exosomes in the pathology processes of HBV infection. Exosomes could serve as essential biomarkers for early detection of HBV infection and HBV-related diseases.Finally, we outline the therapeutic potential of exosomes in anti-HBV therapy, which may provide novel insights into the prevention and treatment of HBV.
Keywords: HBV, exosome, immune response, Virus infection, therapy
Received: 18 Dec 2024; Accepted: 02 Jul 2025.
Copyright: © 2025 Yuan, Huang and Ran. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yan Ran, Fengdu General Hospital, Chongqin, China
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