ORIGINAL RESEARCH article

Front. Cell. Infect. Microbiol.

Sec. Parasite and Host

Volume 15 - 2025 | doi: 10.3389/fcimb.2025.1568349

Proteomics and Phosphoproteomics of Freshwater Mollusks Carcasses Reveal Novel Insights as Potential Food Source

Provisionally accepted
Tielin  WangTielin WangShengkang  WangShengkang WangChangan  ZhuChangan ZhuChanglong  LiChanglong LiXinyi  ZhangXinyi ZhangGongzhen  LiuGongzhen Liu*
  • Linyi University, Linyi, China

The final, formatted version of the article will be published soon.

Cipangopaludina chinensis, Radix auricularia and Nodularia douglasiae are common mollusks living in fresh water, which are widely distributed in lakes and rivers in China. A total of 1382 proteins were identified in carcasses, and 492 proteins were quantified which involved in amino acid nutrition and metabolism, such as Glutamate dehydrogenase, Glyceraldehyde-3-phosphate dehydrogenase and Tyrosinase copper-binding domain-containing protein and so on. Bioinformatics analysis showed these proteins were primarily involved in carbon metabolism, microbial metabolism, ubiquitin mediate proteolysis pathways and RAS signaling pathways. To be notable, this study provides useful information for understanding the differential express proteins among different species. Further more, proteomics analysis of revealed significant novel proteins which helps to improve our understanding of the amino acid metabolism, protein diversity and signaling pathways among these species.

Keywords: freshwater, Mollusks carcases , Proteomics, phosphoproteomics, Cellular components, Molecular functions, Biological Processes, differentially expressed proteins (DEPs)

Received: 29 Jan 2025; Accepted: 19 Jun 2025.

Copyright: © 2025 Wang, Wang, Zhu, Li, Zhang and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Gongzhen Liu, Linyi University, Linyi, China

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