ORIGINAL RESEARCH article
Front. Cell. Infect. Microbiol.
Sec. Clinical Infectious Diseases
Volume 15 - 2025 | doi: 10.3389/fcimb.2025.1587257
This article is part of the Research TopicImmunological Regulation to Enteroviruses and Respiratory Viruses: Infection and Vaccination ResponsesView all 4 articles
Epidemiological characteristics of adenovirus in children in Yancheng, China, 2023-2024
Provisionally accepted
Guoqing Chen1Jin Cao2,3Yingli Qu2Wenyan Tian2Peng Shen1Xuan Liu2Qin Luo2Qinqin Song2Qi Wen2Guangyu Xue2Yuting Hu2Qiangqiang Shi2Lifeng Zhang2Rundong Zhu2Juan Song2*
Jun Han2*- 1Yancheng Center for Disease Prevention and Control, Yancheng, China
- 2Chinese Center For Disease Control and Prevention, Beijing, China
- 3School of Medicine, Anhui University of Science and Technology, Huainan, Anhui Province, China
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Objective To understand the epidemiology and evolutionary characteristics of human adenovirus (HAdV) infecting children in Yancheng, China, during the winter of 2023-2024. Methods HAdV-positive throat swab samples were collected from pediatric patients in Yancheng. The Hexon, Penton base, and Fiber genes were amplified and sequenced for typing and phylogenetic analysis of HAdV. Results 170 HAdV-positive samples were collected and identified from children with acute respiratory infection (ARI) in Yancheng. A total of 133 samples were successfully amplified and sequenced for Hexon, Penton base, and Fiber genes. Phylogenetic analysis showed that HAdV-B3 was the dominant circulating strain, and two strains of B21, one strain of C1 and one strain of C5 were also identified. Conclusion During the winter of 2023-2024, HAdV infecting children in Yancheng was mainly the B3 type.
Keywords: Respiratory infections1, adenovirus2, Epidemiological characteristics3, genetic features4, phylogenetic trees5. 2
Received: 04 Mar 2025; Accepted: 14 May 2025.
Copyright: © 2025 Chen, Cao, Qu, Tian, Shen, Liu, Luo, Song, Wen, Xue, Hu, Shi, Zhang, Zhu, Song and Han. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Juan Song, Chinese Center For Disease Control and Prevention, Beijing, China
Jun Han, Chinese Center For Disease Control and Prevention, Beijing, China
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