REVIEW article
Front. Cell. Infect. Microbiol.
Sec. Extra-intestinal Microbiome
Volume 15 - 2025 | doi: 10.3389/fcimb.2025.1595182
The untapped potential of vaginal microbiome diagnostics in improving women's health
Provisionally accepted
- 1King's College London, London, England, United Kingdom
- 2Medicines and Healthcare products Regulatory Agency (United Kingdom), London, United Kingdom
- 3BiowaveW, Seoul, Republic of Korea
- 4Ewha Womans University, Seoul, Seoul, Republic of Korea
- 5University of Liverpool, Liverpool, North West England, United Kingdom
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Microbiome research has exploded in the last 15 years; however, the main focus has been in the gut microbiome. While understudied, the vaginal microbiome has the potential to significantly contribute to improve women's health. In this paper, we describe the current clinical diagnostic techniques utilizsed in women's health and examine their drawbacks and limitations. We also discuss the potential for new emerging diagnostic technologies based on microbiome analysis that could enable greater precision in diagnosis and personalised treatment. We aadditionallylso suggest the need for standardisation in microbiome analysis and effectively build strengthen the knowledge base in the field to allow for advancements in accurate diagnosis, ultimately improving patient outcomes. This article aims to uncover opportunities in the field that can transform health outcomes for women and outline the actions needed to bring these opportunities into reality, improving women's lives.
Keywords: vaginal microbiome, diagnostics, Standardisation, Women's Health, Personalised treatment
Received: 17 Mar 2025; Accepted: 10 Jun 2025.
Copyright: © 2025 Sofia Da Silva, Anwar, Park, Park, Goodfellow and Sergaki. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Chrysi Sergaki, Medicines and Healthcare products Regulatory Agency (United Kingdom), London, United Kingdom
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.