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ORIGINAL RESEARCH article

Front. Cell. Infect. Microbiol.

Sec. Veterinary and Zoonotic Infection

Volume 15 - 2025 | doi: 10.3389/fcimb.2025.1658759

This article is part of the Research TopicUnveiling Host-Pathogen Interactions: Insights into Animal Cellular Immunity and Novel Diagnostics - Volume IIView all 19 articles

The study of biosafety risk identification and analysis for facilities in biosafety level 3 (BSL-3) laboratories

Provisionally accepted
Bingwang  LvBingwang LvZhiyu  ZhouZhiyu ZhouJinsong  WangJinsong WangQun  NiuQun NiuYuchen  ShiYuchen ShiYanbo  SunYanbo SunHongda  ZhaoHongda ZhaoDongsheng  LuDongsheng LuTao  FanTao Fan*Yang  HuangYang Huang*
  • National Institutes for Food and Drug Control (China), Beijing, China

The final, formatted version of the article will be published soon.

The aim of this study was to identify and analyze biosafety risk points in biosafety level 3 (BSL-3) laboratory facilities to bring awareness to the attention of administrative staff, reduce the biosafety risks, and improve the risk management.The biosafety risk points in BSL-3 facilities were identified by literature searches and field research methods, and the identified biosafety risk points subsequently analyzed using the fault analysis event tree method. Results & Conclusion: Throughout the comprehensive screening and identification of biosafety risk points in BSL-3 laboratory facilities, risk assessments were performed to rank their seriousness. This will help effectively reduce the biosafety risk level of BSL-3 laboratory facilities.

Keywords: Biosafety level 3 laboratory, Facility, biosafety, risk identification, risk analysis

Received: 03 Jul 2025; Accepted: 11 Aug 2025.

Copyright: © 2025 Lv, Zhou, Wang, Niu, Shi, Sun, Zhao, Lu, Fan and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Tao Fan, National Institutes for Food and Drug Control (China), Beijing, China
Yang Huang, National Institutes for Food and Drug Control (China), Beijing, China

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.