ORIGINAL RESEARCH article
Front. Cell. Infect. Microbiol.
Sec. Clinical Infectious Diseases
This article is part of the Research TopicNeglected Tropical Diseases: Drug Targets, and Potential TreatmentsView all 6 articles
Auxin-Mediated biosynthesis of silver nanoparticles: comprehensive characterisation and antibacterial activity analysis
Provisionally accepted
Sahil .1
Anis Ahmad Chaudhary2
Sonia Sorout1Kushi Yadav3
Mohamed A. M. Ali2
Fehmi Boufahja2
Vikram Kumar1SL Kothari1
Devendra Jain4
Kumar Sambhav1*- 1Amity University Rajasthan, Jaipur, India
- 2Imam Muhammad Ibn Saud Islamic University College of Science, Riyadh, Saudi Arabia
- 3Amity University Noida, Noida, India
- 4Maharana Pratap University of Agriculture and Technology, Udaipur, India
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Abstract Silver nanoparticles (AgNPs) possess antibacterial properties, but antibiotic resistance necessitates alternative antimicrobial solutions. This study explores the synthesis of AgNPs using biomolecules, also known as plant growth hormones, "Auxins", including indole-3-acetic acid (IAA) and indole-3-butyric acid (IBA), and evaluates their antibacterial activity. AgNPs were synthesised using IAA, IBA and characterised through UV-Visible spectroscopy, FTIR, Particle Size Analyser, including DLS for hydrodynamic diameter, Zeta potential for surface charge, and FE-SEM. Antibacterial assays were conducted against S. aureus and E. coli. The synthesised AgNPs exhibited controlled composition and enhanced antibacterial activity, particularly against S. aureus. IAA and IBA-mediated AgNPs offer an eco-friendly approach for the synthesis of nanoparticles and demonstrate their potential as antibacterial agents against resistant pathogens.
Keywords: Nanoparticles, Antimicrobial activity, antibiotic, indole-3-acetic acid, Indole-3-butyric acid, green nanotechnology, Auxin-mediated synthesis
Received: 02 Aug 2025; Accepted: 27 Oct 2025.
Copyright: © 2025 ., Chaudhary, Sorout, Yadav, Ali, Boufahja, Kumar, Kothari, Jain and Sambhav. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Kumar Sambhav, kumarsambhav29@gmail.com
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