MINI REVIEW article
Front. Cell. Infect. Microbiol.
Sec. Clinical and Diagnostic Microbiology and Immunology
Volume 15 - 2025 | doi: 10.3389/fcimb.2025.1695284
This article is part of the Research TopicPerspectives in Clinical Microbiology for Combating Multi-drug Resistant Bacterial Infections: 2024/2025View all 11 articles
Perspectives in Clinical Microbiology for Combating Multi-drug Resistant Bacterial Infections
Provisionally accepted
André Mauricio de Oliveira1*
Camila Prósperi de Castro2- 1Federal Center for Technological Education of Minas Gerais, Belo Horizonte, Brazil
- 2Centro Federal de Educacao Tecnologica de Minas Gerais, Belo Horizonte, Brazil
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Multidrug-resistant bacterial infections are a major global threat, exacerbated by globalization and poor sanitation. Bacteria develop resistance through mechanisms like enzymatic degradation, efflux pumps, and horizontal gene transfer. Rapid diagnostics and artificial intelligence are crucial for overcoming the limitations of traditional culture methods. Combating this issue requires novel therapeutic strategies, such as bacteriophages, antimicrobial peptides, and microbiome-based therapies. Ultimately, proper antibiotic use, increased research, and global multidisciplinary cooperation are essential to address this complex challenge.
Keywords: Multidrug-resistant bacterial infections, Broad-spectrum antibiotics, microbiota, Bacteriophages, microbiome
Received: 29 Aug 2025; Accepted: 08 Sep 2025.
Copyright: © 2025 de Oliveira and de Castro. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: André Mauricio de Oliveira, Federal Center for Technological Education of Minas Gerais, Belo Horizonte, Brazil
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