In the original article, there was an error. The term “placental MVM” was used instead of “placental BM.”
A correction has been made to the Introduction, Glucose Transport, Paragraph Number three:
“Pedersen's original hypothesis proposed that maternal hyperglycemia in type 1 diabetes mellitus accelerates placental glucose transfer resulting in fetal hyperglycemia and hyperinsulinemia, which in turn stimulates fetal growth. However, macrosomia is also common in well-controlled diabetic pregnancies suggesting a change in placental function. Women with type 1 diabetes, with first trimester moderate hyperglycemia, showed higher expression of GLUT1 in the BM compared to healthy pregnancies (62). Likewise, a positive correlation has been reported between birth weight and GLUT1 density in the placental BM in type 1 diabetic pregnancies (82). Under in vitro conditions, hyperglycemia partially limits GLUT1 expression and its activity was inversely related to extracellular glucose in primary cultured human trophoblast from uncomplicated pregnancies (83). In addition, elevated glucose concentration promotes the translocation of the GLUT transporters from the cell surface to the intracellular compartment as a mechanism to downregulate glucose uptake (84) in cultured trophoblast cells. An interaction of insulin and glucose may be important in determining in vivo expression of placental GLUT isoforms.”
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Summary
Keywords
obesity, gestational diabetes, placental transport, syncytiotrophoblast, fetal growth
Citation
Castillo-Castrejon M and Powell TL (2019) Corrigendum: Placental Nutrient Transport in Gestational Diabetic Pregnancies. Front. Endocrinol. 10:5. doi: 10.3389/fendo.2019.00005
Received
29 November 2018
Accepted
09 January 2019
Published
28 January 2019
Volume
10 - 2019
Edited and reviewed by
Hubert Vaudry, Université De Rouen, France
Updates
Copyright
© 2019 Castillo-Castrejon and Powell.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Theresa L. Powell theresa.powell@ucdenver.edu
This article was submitted to Neuroendocrine Science, a section of the journal Frontiers in Endocrinology
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