CORRECTION article

Front. Endocrinol., 21 March 2024

Sec. Reproduction

Volume 15 - 2024 | https://doi.org/10.3389/fendo.2024.1397017

Corrigendum: Dose-dependent stimulation of human follicular steroidogenesis by a novel rhCG during ovarian stimulation with fixed rFSH dosing

  • 1. Laboratory of Reproductive Biology, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark

  • 2. Global Biometrics, Ferring Pharmaceuticals A/S, Copenhagen, Denmark

  • 3. Reproductive Medicine & Maternal Health, Ferring Pharmaceuticals A/S, Copenhagen, Denmark

  • 4. Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

In the published article, there was an error in Table 2 as published. The incorrect data was included in the last row of the table for 17-OH-progesterone as these were a duplicate of the testosterone values from a few rows above. The corrected table in this corrigendum (Table 1) and its caption Steroid hormone concentrations (nmol/L) in serum and follicle fluid and their relative increase upon CG beta treatment appear below on the next page.

Table 1

TREATMENT GROUP (hCG dose)
ENDPOINTPlacebo (0 µg)1 µg2 µg4 µg8 µg12 µg
EstradiolSerum2.9 (100)3.8* (133)4.3* (147)4.8* (166)6.2* (215)5.9* (202)
FF1891 (100)3664* (194)4352* (230)5523* (292)6929* (366)8047* (426)
AndrostenedioneSerum6.2 (100)8.3* (134)8.9* (144)10.4* (169)12.3* (199)11.9* (194)
FF13.6 (100)19.4* (142)23.7* (174)32.7* (240)49.2* (361)54.6* (400)
TestosteroneSerum1.7 (100)2.3* (136)2.5* (145)2.9* (171)3.5* (209)3.3* (196)
FF6.0 (100)17.8* (294)22.9* (380)37.6* (623)58.9* (977)63.2* (1047)
ProgesteroneSerum27.6 (100)23.8 (86)22.3* (81)19.5* (71)20.5* (74)19.6* (71)
FF40090 (100)38130 (95)34660 (86)38340 (96)32750 (82)46220 (115)
17-OH-progesteroneSerum16.9 (100)20.1* (119)22.1* (131)22.5* (133)26.8* (158)25.0* (148)
FF4230 (100)5210* (123)5460* (129)6490* (153)6860* (162)8210* (194)

Steroid hormone concentrations (nmol/L) in serum and follicle fluid and their relative increase upon CG beta treatment.

Mean values of steroid hormones (nmol/L) in serum and follicle fluid (FF) in relation to treatment group. The relative increase (%) of steroid hormone levels is indicated in parenthesis. *Denotes statistically significant difference compared with placebo (p<0.05). Results for FF and serum hormones are at oocyte retrieval. Steroid hormones were measured by different assays in serum and FF. hCG, human choriogonadotropin.

The authors sincerely apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Statements

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Summary

Keywords

Steroidogenesis, FE 999302, recombinant hCG, ovarian stimulation, cumulus cells, single nucleotide polymorphisms

Citation

Bøtkjær JA, Kristensen SG, Olesen HØ, Larsson P, Mannaerts B and Andersen CY (2024) Corrigendum: Dose-dependent stimulation of human follicular steroidogenesis by a novel rhCG during ovarian stimulation with fixed rFSH dosing. Front. Endocrinol. 15:1397017. doi: 10.3389/fendo.2024.1397017

Received

06 March 2024

Accepted

08 March 2024

Published

21 March 2024

Approved by

Frontiers Editorial Office, Frontiers Media SA, Switzerland

Volume

15 - 2024

Updates

Copyright

*Correspondence: Jane Alrø Bøtkjær,

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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