REVIEW article
Front. Endocrinol.
Sec. Pediatric Endocrinology
Volume 16 - 2025 | doi: 10.3389/fendo.2025.1475465
This article is part of the Research TopicPolycystic Ovarian Syndrome in AdolescenceView all articles
Adipokines as biochemical marker of polycystic ovary syndrome in adolescents -review
Provisionally accepted
Dominika Orszulak*
Kacper Niziński
Aleksandra Matonóg
Maja Zięba-Domalik
Rafał Stojko
Agnieszka Drosdzol-Cop- Department of Gynecology, Obstetrics and Oncological Gynecology, Faculty of Health Sciences in Katowice, Medical University of Silesia, Katowice, Silesian, Poland
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Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders affecting approximately 10% of adolescent women. According to literature data, in the case of coexistence of obesity and PCOS, menstrual cycle disorders are much more common. One of the probable reasons is the activity of adipose tissue, which secretes many types of adipokines that may have a negative impact on hormonal and metabolic functions. This article reviews the literature on the role of adipokines in the etiopathogenesis of PCOS in adolescent girls. The literature base consisted of published articles -clinical trials, meta-analyses, reviews and systematic reviews. The databases -PubMed, ScienceDirect, EMBASE were searched.
Keywords: Polycystic Ovary Syndrome, Adipokines, adolescents, Leptin, Adiponectin
Received: 03 Aug 2024; Accepted: 01 May 2025.
Copyright: © 2025 Orszulak, Niziński, Matonóg, Zięba-Domalik, Stojko and Drosdzol-Cop. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Dominika Orszulak, Department of Gynecology, Obstetrics and Oncological Gynecology, Faculty of Health Sciences in Katowice, Medical University of Silesia, Katowice, 40-211, Silesian, Poland
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