CORRECTION article
Front. Endocrinol.
Sec. Bone Research
Volume 16 - 2025 | doi: 10.3389/fendo.2025.1690095
Mechanism of action of curculigoside ameliorating osteoporosis: an analysis based on network pharmacology and experimental validation
Provisionally accepted
- 1First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, China
- 2Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China
- 3Shandong University of Traditional Chinese Medicine, Jinan, China
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MMP3, MMP9, IL-6, and caspase-3, acting on signaling pathways including Rap1 and TNF. These results indicate that curculigoside exhibits multi-target and multi-pathway characteristics in osteoporosis treatment, providing a theoretical basis for further clinical investigation.
Keywords: Curculigoside, Osteoporosis, Network Pharmacology, molecular docking, Micro CT technology
Received: 21 Aug 2025; Accepted: 29 Aug 2025.
Copyright: © 2025 Wei, Zhang, Lou, Li and Cao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Hui Cao, Shandong University of Traditional Chinese Medicine, Jinan, China
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