REVIEW article
Front. Endocrinol.
Sec. Gut Endocrinology
Research progress of gut microbiota and its metabolites in polycystic ovary syndrome
Provisionally accepted
- 1Chongqing Health Center for Women and Children, Chongqing, China
- 2The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Polycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic diseases in women of reproductive age, but its specific pathogenesis remains unknown. More and more evidence indicates that PCOS may be a complex polymorphic disease, influenced by epigenetic and environmental factors, including diet and lifestyle. This review focuses on the role of the gut microbiota and its metabolites in PCOS, a topic that has gained significant attention recently due to the established link between the gut microbiome and metabolic disorders.
Keywords: Polycystic Ovary Syndrome, Gut Microbiota, Short Chain Fatty Acids, lipopolysaccharide, Bile acids, Trimethylamine N-oxide, Branched chain amino acid, intestinal fungus
Received: 08 Sep 2025; Accepted: 30 Nov 2025.
Copyright: © 2025 Qin, Guo, Tan, Li and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Ke Li
Jiayu Huang
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