SYSTEMATIC REVIEW article
Front. Endocrinol.
Sec. Clinical Diabetes
This article is part of the Research TopicDiabetes and Pregnancy: Optimizing Maternal and Fetal Outcomes through Advanced TechnologiesView all 4 articles
The Impact of Mobile Health (mHealth) Interventions on Maternal-Neonatal Outcomes in Women with Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis
Provisionally accepted
- 1Jinhua Maternal and Child Health Care Hospital, Jinhua, China
- 2Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China
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Background: Gestational diabetes mellitus (GDM), a prevalent complication during pregnancy, is closely associated with an elevated risk of adverse maternal and neonatal outcomes. Mobile health (mHealth) technologies have emerged as convenient tools for GDM management; however, their clinical efficacy in improving maternal and neonatal outcomes among GDM-affected pregnant individuals remains to be comprehensively evaluated. Objective: The study aims to evaluate the effectiveness of mHealth interventions in improving maternal and neonatal outcomes among pregnant individuals with GDM. Methods: This study systematically searched the PubMed, Web of Science, Scopus, Cochrane Library, and EMBASE databases from their inception to July 23, 2025. Two researchers independently screened the studies, extracted data, and assessed quality. All data analyses were performed using STATA 17.0 software. Results: Compared with routine care, mHealth interventions significantly reduced the risk of cesarean section (OR 0.76, 95% CI 0.63–0.91) and emergency cesarean (OR 0.55, 95% CI 0.39–0.77) among women with GDM. Additionally, a significant reduction in the risk of composite neonatal complications was observed (OR 0.63, 95% CI 0.44–0.89). Furthermore, mHealth interventions significantly improved 2-hour postprandial blood glucose levels (SMD −0.36, 95% CI −0.53 to −0.19). A trend toward reduced gestational weight gain was also noted in the mHealth intervention group (SMD −0.37, 95% CI −0.83 to 0.08). Conclusion: mHealth interventions can reduce the risk of cesarean section rate and emergency cesarean section, as well as the risk of composite neonatal complications. mHealth interventions may also improve two-hour postprandial blood glucose control in pregnant women with GDM and can effectively supplement conventional clinical care for GDM.
Keywords: gestational diabetes mellitus, Maternal and neonatal outcomes, mobile health interventions, Systematic review, Meta-analysis
Received: 22 Sep 2025; Accepted: 03 Dec 2025.
Copyright: © 2025 Yang, Yang, Nie and Lou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jianyi Lou
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