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EDITORIAL article

Front. Endocrinol.

Sec. Cancer Endocrinology

This article is part of the Research TopicNew molecular pathways in thyroid biology: Role of coding and noncoding genes in thyroid pathophysiology, volume IIView all 11 articles

Editorial: New molecular pathways in thyroid cancer and pathophysiology: Role of coding and noncoding genes, volume II

Provisionally accepted
  • 1University of São Paulo, São Paulo, Brazil
  • 2Universidad Nacional de Cordoba Facultad de Ciencias Quimicas, Córdoba, Argentina

The final, formatted version of the article will be published soon.

explore recent advances to the understanding of thyroid biology, especially those involved in thyroid oncogenesis and progression.Thyroid cancer is often a curable disease being most cases from papillary thyroid cancer, the most common variant, which is also classified as a well-differentiated tumor (DTC) that maintains certain similarity to normal thyroid gland, mainly the ability to concentrate iodine. However, a small fraction of PTC may exhibit a more aggressive behavior with enhanced probability of recurrence and of evolving into poor outcomes. In In sum, we hope the Research Topic "New molecular pathways in thyroid cancer and pathophysiology: Role of coding and noncoding genes, Volume II" have contributed to accelerate the understanding of this thrilling field of thyroid biology, and that further studies can bring fruitful applications for thyroid pathologies treatment.

Keywords: thyroid cancer (THCA), Tumor microenvironment - TME, metastasis, circRNA, PANoptosis, FNA (fine needle aspiration), Molecular analyses

Received: 21 Oct 2025; Accepted: 23 Oct 2025.

Copyright: © 2025 Fuziwara and Nicola. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Cesar Seigi Fuziwara, cesar.fuziwara@usp.br

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.