Your new experience awaits. Try the new design now and help us make it even better

RETRACTION article

Front. Endocrinol., 27 November 2025

Sec. Cellular Endocrinology

Volume 16 - 2025 | https://doi.org/10.3389/fendo.2025.1751575

Retraction: LRP6 knockdown ameliorates insulin resistance via modulation of autophagy by regulating GSK3β signaling in human L02 hepatocytes

This article is a retraction of:

  1. RETRACTED: LRP6 Knockdown Ameliorates Insulin Resistance via Modulation of Autophagy by Regulating GSK3β Signaling in Human LO2 Hepatocytes

    1. Read original article
Frontiers Editorial Office* Frontiers Editorial Office*

    A Retraction of the Original Research Article
    LRP6 knockdown ameliorates insulin resistance via modulation of autophagy by regulating GSK3β signaling in human LO2 hepatocytes

    By Li L, Xue J, Wan J, Zhou Q, Wang S, Zhou Y, Zhao H and Wang X (2019) Front. Endocrinol. 10:73. doi: 10.3389/fendo.2019.00073

    The journal retracts the February 19 2019 article cited above.

    Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers’ policies.

    This retraction was approved by the Chief Executive Editor of Frontiers. The authors received a communication regarding the retraction and had a chance to respond. This communication has been recorded by the publisher.

    Frontiers would like to thank the users on PubPeer for bringing the published article to our attention.

    Citation: Frontiers Editorial Office (2025) Retraction: LRP6 knockdown ameliorates insulin resistance via modulation of autophagy by regulating GSK3β signaling in human L02 hepatocytes. Front. Endocrinol. 16:1751575. doi: 10.3389/fendo.2025.1751575

    Received: 21 November 2025; Accepted: 21 November 2025;
    Published: 27 November 2025.

    Approved by:

    Frontiers Editorial Office, Frontiers Media SA, Switzerland

    Copyright © 2025 Frontiers Editorial Office. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    *Correspondence: Frontiers Editorial Office, cmVzZWFyY2guaW50ZWdyaXR5QGZyb250aWVyc2luLm9yZw==

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.