ORIGINAL RESEARCH article
Front. Endocrinol.
Sec. Bone Research
Knowledge, attitudes, and practices of patients with chronic kidney disease toward osteosarcopenia
Chunmei Yang 1
Wei Wei 1
Wenhui Chai 1
Tao Li 1
Yue Ma 1
Xuan Wang 1
Mei Liu 2
Bumaryam Abla 1
Hongtao Cai 1
Ping Li 1
Ying Liu 1
Jiao Liu 1
1. People's Hospital of Changji Hui Autonomous Prefecture, Xinjiang, China
2. Changji Hui Autonomous Prefecture Hospital of Traditional Chinese Medicine, Xinjiang, China
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Abstract
Objective: To investigate the knowledge, attitudes, and practices of patients with chronic kidney disease regarding osteosarcopenia. Methods: This cross-sectional survey was conducted among patients with chronic kidney disease at People's Hospital of Changji Hui Autonomous Prefecture, Xinjiang from February to September, 2025. Demographic information was obtained, and KAP scores were assessed using a questionnaire. The differences in KAP toward osteosarcopenia were compared among patients with different demographic characteristics. The factors influencing knowledge, attitudes, and practices were determined using logistic regression analyses. A path analysis was conducted to examine the relationships between the knowledge, attitudes, and practices dimensions. Results: This study enrolled 585 participants. The mean knowledge score was 6.33±5.48 (on a maximum of 20, 31.65%), the mean attitude score was 34.33±5.98 (on a maximum of 50, 68.66%), and the mean practice score was 27.89±9.82 (on a maximum of 50, 55.78%). Being single (OR=0.532, 95% CI: 0.322-0.876), requiring partial assistance with activities of daily living (OR=0.247, 95% CI: 0.144-0.424), being bedridden (OR=0.055, 95% CI: 0.012-0.246), score 9-12 for social support and environmental factors (OR=1.674, 95% CI: 1.000-2.804), score 13-20 for social support and environmental factors (OR=5.771, 95% CI: 2.971-11.209), score 5.0-6.9 for confidence level in preventing osteosarcopenia (OR=3.933, 95% CI: 2.179-7.101), and score 7.0-10.0 for confidence level in preventing osteosarcopenia (OR=4.227, 95% CI: 2.174-8.216) were independently associated with the knowledge scores. Knowledge had a direct and positive influence on attitude (β=0.682, P<0.001) and practice (β=0.523, P<0.001). Attitude positively directly influenced practice (β=0.344, P<0.001). Knowledge had a positive indirect influence on practice through attitude (β=0.235, P<0.001). Conclusion: Patients with chronic kidney disease had suboptimal knowledge, attitudes, and practices toward osteosarcopenia. Interventions should be designed to improve their knowledge, attitudes, and practices toward osteosarcopenia.
Summary
Keywords
Attitude, Chronic Kidney Disease, Cross-sectional study, Health Knowledge, osteosarcopenia, Practice
Received
04 November 2025
Accepted
18 February 2026
Copyright
© 2026 Yang, Wei, Chai, Li, Ma, Wang, Liu, Abla, Cai, Li, Liu and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Chunmei Yang
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