Frontiers in Genetics

Original Research

Published on 17 Oct 2025

Association of APOA5 rs2075291 and CIDEB rs2144492 polymorphisms with hypertriglyceridemia in individuals with traditional Chinese medicine dampness syndrome: a case-control study

in Applied Genetic Epidemiology

Na Liu
Hongli Zeng
Xiangsheng Cai
Shuo Yang
Xinyan Chen
Guli Jiang
Jiamin Yuan
Jianxiong Cai
Hui Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1654501

1,511 views

Original Research

Published on 16 Oct 2025

A novel deletion upstream of POU3F4 in a Chinese family with X-linked deafness 2 and a literature review

in Genetics of Common and Rare Diseases

Yanting Yang
Shengwen Huang
Yao Liu
Dan Mu
Ting Bai
Xiaosha Jing
Lingling Xing
Hongqian Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1641999

1,987 views

Original Research

Published on 16 Oct 2025

CGSDA: inferring snoRNA-disease associations via ChebNetII and GatedGCN

in Computational Genomics

Yongfu Zou
Yusong Lu
Shanghui Lu
Zhanliang Wei
Le Li
Shuilin Liao
Ting Zeng
Yi Zhang
Rui Miao

Frontiers in Genetics

doi 10.3389/fgene.2025.1684484

1,539 views

Original Research

Published on 16 Oct 2025

A novel dinucleotide variant at 5′ splice sites in the F8 gene causes exon 19 skipping in a Chinese family with hemophilia A

in Statistical Genetics and Methodology

Xunzhao Zhou
Qi Yang
Qiuli Chen
Sheng Yi
Shengkai Wei
Jingsi Luo
Dahua Meng
Zailong Qin
Shujie Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1686184

1,777 views

Original Research

Published on 16 Oct 2025

Transcriptome profiling of hypothalamus-pituitary-ovary axis provides insights into egg-laying interval differences between european meat pigeons and shiqi pigeons

in Livestock Genomics

Xinlei Wang
Liyu Yang
Ruiting Li
Liheng Zhang
Zhanbing Han
Runzhi Wang
Qiang Li
Dingding Zhang
Mingjun Yang
Pengkun Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1676255

2,086 views

Original Research

Published on 16 Oct 2025

Whole exome sequencing identifies concurrent LDLR and ABCG8 mutations in a Saudi family with familial hypercholesterolemia and Sitosterolaemia

in Genetics of Common and Rare Diseases

Abdulrahman Hummadi
Dhayf Alrahman Mutawwam
Babajan Banaganapalli
Fai Alsubhi
Naji J. Aljohani
Ali J. Alhagawy
Turki Algohani
Ibrahim Fallatah
Mohammed Y. Daghriry
Rawan K. Alharbi

Frontiers in Genetics

doi 10.3389/fgene.2025.1679594

2,920 views

Original Research

Published on 16 Oct 2025

Identification and validation of selenium metabolism-related genes in lung adenocarcinoma prognosis using bioinformatics analysis

in Cancer Genetics and Oncogenomics

Yun Chen
Ping Li
Yang Wang
Shuai Shen
Ni Chen
Hao Peng
Zheyuan Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1655262

1,916 views

Brief Research Report

Published on 15 Oct 2025

A rare subtype of lynch syndrome familial with co-mutation of EpCAM c.344T>C, MSH2 c.2744A>G, PMS2 c.1408C>T and APC c.5465T>A, case report and literature review

in Cancer Genetics and Oncogenomics

Guiyu Lu
Ting Pan
Cuidong Deng
Xiaoqian Wan
Zihan Wang
Tengyue Hu
Xianshuo Cheng
Jian Dong

Frontiers in Genetics

doi 10.3389/fgene.2025.1667899

2,457 views

Original Research

Published on 15 Oct 2025

Clinical and genetic analysis of MOCOS gene-related hypouricemia

in Genetics of Common and Rare Diseases

Huifang Peng
Ping Tu
Qiaobo Ma
Jinpeng Tang
Wannv Xiao
Xinyu Hu
Yingyu Zhang
Hongwei Jiang

Frontiers in Genetics

doi 10.3389/fgene.2025.1636032

1,951 views

Original Research

Published on 15 Oct 2025

Epitranscriptome-wide profiling identifies RNA editing events regulated by ADAR1 that are associated with DNA repair mechanisms in human TK6 cells

in RNA

Akito Yoshida
Yuqian Song
Hotaru Takaine
Sujin Song
Nonoka Konishi
Yu-Hsien Hwang-Fu
Zachary Johnson
Kiyoe Ura
Akira Sassa

Frontiers in Genetics

doi 10.3389/fgene.2025.1663827

14,830 views
1 citation

Review

Published on 14 Oct 2025

CircZFR functions in cancer from molecular networks to precision therapy

in RNA

Jinniang Nan
Min Li
Xinru Li
Yuqing Guo
Ziye Cai
Zekang Deng
Chengyi Zhan
Jiacheng Li
Shuying Liu
Ziyi Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1694220

2,421 views
1 citation

Original Research

Published on 14 Oct 2025

Identification of key genes for heart failure in dilated cardiomyopathy in different populations

in Computational Genomics

Yue Yu
Chentian Xue
Dong Ji
Wei Sheng
Xiang Gao
Xize Wu
Chengyan Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1618390

2,878 views

Case Report

Published on 14 Oct 2025

Ataxia, intentional tremor and hypotonia syndrome caused by a novel POU4F1 gene mutation: a case report

in Neurogenomics

Qisheng Hu
Feng Zhu
Wanfen Wang
Yihang Xu
Haiyan Ren
Yanni Zheng
Yiqing Jiang
Shaofa Ke

Frontiers in Genetics

doi 10.3389/fgene.2025.1702803

1,850 views

Review

Published on 14 Oct 2025

Gene-LLMs: a comprehensive survey of transformer-based genomic language models for regulatory and clinical genomics

in Computational Genomics

P. Balakrishnan
A. Anny Leema
V. Dhivya Shree
C. Mohammad Saad
A. Mohan Babu

Frontiers in Genetics

doi 10.3389/fgene.2025.1634882

6,634 views

Correction

Published on 13 Oct 2025

Correction: DeepRNAac4C: a hybrid deep learning framework for RNA N4-acetylcytidine site prediction

in Computational Genomics

Guohua Huang
Runjuan Xiao
Chunying Peng
Jinyun Jiang
Weihong Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1704319

936 views

Original Research

Published on 13 Oct 2025

Transcriptomic profiling reveals macrophage gene signatures associated with lactylation-related pathways in chronic obstructive pulmonary disease

in Epigenomics and Epigenetics

Hui Guo
Weilin Sun
Fang Zhao
Yang Yu
Xiaoyun Zhao
Daqiang Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1653163

4,040 views

Editorial

Published on 13 Oct 2025

Editorial: The neurogenetics of brain wiring

in Behavioral and Psychiatric Genetics

Ting Feng
Wenfeng Chen
Aja McDonagh
Zhenxing Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1699487

2,091 views

Case Report

Published on 13 Oct 2025

Thoracic aortic aneurysm combined with intracranial vascular abnormalities caused by dual mutations in MYLK and FBN2: a case report

in Genetics of Common and Rare Diseases

Maorong Cai
Yang Liu
Zhaodi Liao
Yiping Wu
Jiantong Jiao

Frontiers in Genetics

doi 10.3389/fgene.2025.1672342

1,768 views

Case Report

Published on 10 Oct 2025

Case Report: Practical approach to differentiating juvenile parkinsonism of genetic cause and drug-induced parkinsonism in adolescents: a case series and literature review

in Genetics of Common and Rare Diseases

Ioana Grigore
Lăcrămioara Ionela Butnariu
Thomas Gabriel Schreiner
Vasile Valeriu Lupu
Ancuta Lupu
Ludmila Darie
Cătălin Prăzaru
Elena Țarcă
Setalia Popa
Ecaterina Grigore

Frontiers in Genetics

doi 10.3389/fgene.2025.1672445

1,993 views
1 citation

Editorial

Published on 09 Oct 2025

Editorial: Application of next-generation sequencing in clinical settings

in Human and Medical Genomics

Zhi Chai
Han Mei
Quan Li
Iram Maqsood
Jingxian Cai
Marilyn M. Li
Feng Xu
Xiaonan Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1700975

4,105 views

Original Research

Published on 09 Oct 2025

The molecular characterization of seven novel GLI family zinc finger 3 (GLI3) variants in Chinese families with limb malformations

in Genetics of Common and Rare Diseases

Siyuan Tao
Xuyu Gu
Xiaodong Wang
Xiaofang Shen
Xiuli Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1650790

1,569 views

Original Research

Published on 08 Oct 2025

GTAT-GRN: a graph topology-aware attention method with multi-source feature fusion for gene regulatory network inference

in Computational Genomics

Shuran Wang
Lilian Zhang
Lutao Gao
Yao Rao
Jie Cui
Linnan Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1668773

2,702 views

Original Research

Published on 08 Oct 2025

Integrated transcriptomic and single-cell RNA sequencing identifies lysosomal ion channel genes as potential biomarkers for Alzheimer’s disease

in Neurogenomics

Xin Wang
Zelin Wu
Shaoli Wei
Xinran Zhao
Juan Lin
Fang Zhao
Xiaolei Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1676565

2,663 views

Data Report

Published on 08 Oct 2025

Catalogue of mitotic chromosome-associated small RNAs in mouse 3T3 cell line

in Human and Medical Genomics

Bishan Ye
Yicong Meng
Le Zhang
Yongzhuo Deng
Xuesong Zheng
Yihang Shen
Xinhui Li
Hua Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1559795

1,759 views

16,577 articles

articles

Association of APOA5 rs2075291 and CIDEB rs2144492 polymorphisms with hypertriglyceridemia in individuals with traditional Chinese medicine dampness syndrome: a case-control study

A novel deletion upstream of POU3F4 in a Chinese family with X-linked deafness 2 and a literature review

CGSDA: inferring snoRNA-disease associations via ChebNetII and GatedGCN

A novel dinucleotide variant at 5′ splice sites in the F8 gene causes exon 19 skipping in a Chinese family with hemophilia A

Transcriptome profiling of hypothalamus-pituitary-ovary axis provides insights into egg-laying interval differences between european meat pigeons and shiqi pigeons

Whole exome sequencing identifies concurrent LDLR and ABCG8 mutations in a Saudi family with familial hypercholesterolemia and Sitosterolaemia

Identification and validation of selenium metabolism-related genes in lung adenocarcinoma prognosis using bioinformatics analysis

A rare subtype of lynch syndrome familial with co-mutation of EpCAM c.344T>C, MSH2 c.2744A>G, PMS2 c.1408C>T and APC c.5465T>A, case report and literature review

Clinical and genetic analysis of MOCOS gene-related hypouricemia

Epitranscriptome-wide profiling identifies RNA editing events regulated by ADAR1 that are associated with DNA repair mechanisms in human TK6 cells

CircZFR functions in cancer from molecular networks to precision therapy

Identification of key genes for heart failure in dilated cardiomyopathy in different populations

Ataxia, intentional tremor and hypotonia syndrome caused by a novel POU4F1 gene mutation: a case report

Gene-LLMs: a comprehensive survey of transformer-based genomic language models for regulatory and clinical genomics

Correction: DeepRNAac4C: a hybrid deep learning framework for RNA N4-acetylcytidine site prediction

Transcriptomic profiling reveals macrophage gene signatures associated with lactylation-related pathways in chronic obstructive pulmonary disease

Editorial: The neurogenetics of brain wiring

Thoracic aortic aneurysm combined with intracranial vascular abnormalities caused by dual mutations in MYLK and FBN2: a case report

Case Report: Practical approach to differentiating juvenile parkinsonism of genetic cause and drug-induced parkinsonism in adolescents: a case series and literature review

Editorial: Application of next-generation sequencing in clinical settings

The molecular characterization of seven novel GLI family zinc finger 3 (GLI3) variants in Chinese families with limb malformations

GTAT-GRN: a graph topology-aware attention method with multi-source feature fusion for gene regulatory network inference

Integrated transcriptomic and single-cell RNA sequencing identifies lysosomal ion channel genes as potential biomarkers for Alzheimer’s disease

Catalogue of mitotic chromosome-associated small RNAs in mouse 3T3 cell line