Frontiers in Genetics

Original Research

Published on 01 Oct 2025

Using buccal methylomic data to create explainable aging clocks as well as classifiers and regressors for lifestyle and demographic factors

in Epigenomics and Epigenetics

Maxim N. Shokhirev
Adiv A. Johnson

Frontiers in Genetics

doi 10.3389/fgene.2025.1637186

4,467 views

Editorial

Published on 30 Sep 2025

Editorial: Genetic dissection and improvement of crop quality and stress adaptation

in Genetics and Genomics of Plants and Plant-Associated Organisms

Liwei Zheng
Hangkai Zhang
Songwen Zhang
Yingpeng Hua
Lihu Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1694599

2,889 views

Original Research

Published on 30 Sep 2025

Prenatal diagnosis and molecular characterization of PKHD1 variants in two Chinese fetuses with Caroli disease/syndrome

in Genetics of Common and Rare Diseases

Hui Huang
Sheng Zhao
Dan Wang
Shengbao Pan
Fang Liu
Peiwen Chen
Xinlin Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1651306

3,521 views

Original Research

Published on 29 Sep 2025

Understanding stakeholders’ experience with sickle cell disease by social media listening across Europe

in ELSI in Science and Genetics

Daniel Brás
Celeste Bento
Sathyaraj Asaithambi
Jyoti Chauhan
Ines Moital

Frontiers in Genetics

doi 10.3389/fgene.2025.1629510

4,600 views

Original Research

Published on 29 Sep 2025

Comparative genome-wide analysis of Ovis aries in Saudi Arabia highlighting inbreeding and genetic isolation of the Najdi sheep breed

in Livestock Genomics

Abdulrahman K. Aldawish
Mohanad A. Ibrahim
Faisal M. Alsubaie
Quaiser Saquib
Mohammed Fahad Albeshr

Frontiers in Genetics

doi 10.3389/fgene.2025.1646127

4,396 views

Original Research

Published on 29 Sep 2025

Immune-molecular nexus in reproductive disorders: mechanisms linking POI and RSA

in Computational Genomics

Chen Chen
Xinyue Zhang
Wenxin Li
Yueqin Liu
Dan Zhao
Subo Zhang
Xiaolan Zhu

Frontiers in Genetics

doi 10.3389/fgene.2025.1652519

2,972 views

Original Research

Published on 29 Sep 2025

LncRNA and mRNA expression characteristic and bioinformatic analysis in anemic diabetic foot ulcers

in RNA

Jiayu Lin
Jingying Wang
Bo Liang

Frontiers in Genetics

doi 10.3389/fgene.2025.1603315

1,871 views
1 citation

Original Research

Published on 26 Sep 2025

ZmEXPB7, a β-expansin gene, contributes to drought tolerance in Arabidopsis

in Genomics of Plants and the Phytoecosystem

Jing Xiong
Xianqiu Wang
Xueling Ye
Changying Liu
Jialiang Han

Frontiers in Genetics

doi 10.3389/fgene.2025.1688658

3,624 views
1 citation

Methods

Published on 26 Sep 2025

CNAdjust: enhancing CNA calling accuracy through systematic baseline adjustment

in Cancer Genetics and Oncogenomics

Hangjia Zhao
Michael Baudis

Frontiers in Genetics

doi 10.3389/fgene.2025.1674138

2,736 views

Methods

Published on 26 Sep 2025

A partially automated method for DNA extraction from marmoset hair follicles to avoid blood chimerism

in Genomic Assay Technology

Alexandra M. Stendahl
Qiangge Zhang
Ana C. Lima
Curtis Mello
James Nemesh
Sam Peterson
Jenna Castro
Fritzie T. Celino-Brady
Karina Ray
Xian Gao

Frontiers in Genetics

doi 10.3389/fgene.2025.1608504

4,506 views

Original Research

Published on 26 Sep 2025

Developing prognostic models for cholesterol-related genes linked with immune infiltration in prostate cancer

in Cancer Genetics and Oncogenomics

Jie Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1604113

2,781 views

Original Research

Published on 25 Sep 2025

Association between LRRK2 gene polymorphisms and Parkinson’s disease progression in a Chinese Han population

in Genetics of Common and Rare Diseases

Zhaoting Zhang
Lei Geng
Jiuxin Gao
Ruifang She
Zhonglin Ge
Jianhua Liu
Qianqian He
Bing Fu
Weiguo Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1662348

2,578 views

Original Research

Published on 25 Sep 2025

Functional analysis of MEIS2 splice site variant c.438 + 1G>T in a congenital heart patient

in Genetics of Common and Rare Diseases

Chenyu Xu
Junjuan Li
Xinghui Ma
Wenqi Li
Bo Jiang
Hua Bai
Fuhong Wu
Chunlian Liu
Jiwei Gu

Frontiers in Genetics

doi 10.3389/fgene.2025.1629159

2,046 views

Original Research

Published on 25 Sep 2025

MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma

in Cancer Genetics and Oncogenomics

Rong Qi
Chen Fang
Penghui Liu
Weiguo Gu
Chao Shi
Guohua Zhang
Feng Qiu

Frontiers in Genetics

doi 10.3389/fgene.2025.1615018

2,591 views

Original Research

Published on 25 Sep 2025

Concordance of an in-house 2-steps PCR-SSP and nanopore sequencing for HLA-B57:01 and HLA-B58:01 typing: a comparative study

in Pharmacogenetics and Pharmacogenomics

Nattapong Intharuangrung
Chonticha Sirikul
Pattaraporn Nimsamer
Thidathip Wongsurawat
Auttachai Saejia
Nampeung Anukul

Frontiers in Genetics

doi 10.3389/fgene.2025.1649990

4,647 views

Original Research

Published on 25 Sep 2025

Cross-modal predictive modeling of multi-omic data in 3D airway organ tissue equivalents during viral infection

in Computational Genomics

Mostafa Rezapour
Patrick M. McNutt
David A. Ornelles
Stephen J. Walker
Sean V. Murphy
Anthony Atala
Metin Nafi Gurcan

Frontiers in Genetics

doi 10.3389/fgene.2025.1658577

3,116 views
1 citation

Original Research

Published on 24 Sep 2025

Identifying metabolism-related genes in liver cancer through weighted gene co-expression network analysis and machine learning

in Cancer Genetics and Oncogenomics

Taorui Wang
Zijun Lai
Shengjun Tang
Lehang Lin
Mingjiao Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1654459

4,288 views

Review

Published on 24 Sep 2025

Mechanisms of circular RNAs in diabetic cardiomyopathy: biological characteristics and clinical prospects

in RNA

Yunfei Guan
Quancheng Han
Meng Wang
Jianguo Xu
Xiujuan Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1665571

3,560 views
2 citations

Original Research

Published on 24 Sep 2025

Intrauterine phenotype, genetic analysis, and pregnancy follow-up of fetuses with the 16p12.2 microdeletion

in Genetics of Common and Rare Diseases

Meiying Cai
Na Lin
Hailong Huang
Wenqiang You
Nan Guo
Liangpu Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1595399

2,066 views

Case Report

Published on 23 Sep 2025

Case Report: a family report of hereditary pancreatitis caused by SPINK1 and PRSS1 gene mutations

in Genetics of Common and Rare Diseases

Jing Xu
Ying Hu
Banghui Xiao
Juan He
Miao Zhang
Rui Wang
Nianchun Peng

Frontiers in Genetics

doi 10.3389/fgene.2025.1610108

3,330 views

Original Research

Published on 22 Sep 2025

Constructing a novel mitochondrial-related gene signature for predicting survival and evaluating the tumor immune microenvironment in clear cell renal cell carcinoma

in Cancer Genetics and Oncogenomics

Jiaxuan Qin
Lijian Zhang
Bowen Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1543593

4,262 views

Original Research

Published on 22 Sep 2025

Identification of platelet function-related genes in STEMI patients

in Computational Genomics

Jingjing Zhu
Shuangya Yang
Qing Guo
Yifan Yang
Bei Shi

Frontiers in Genetics

doi 10.3389/fgene.2025.1651794

1,959 views

Hypothesis and Theory

Published on 22 Sep 2025

Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation

in Evolutionary and Population Genetics

Todor Chobanov
Svetoslav Stamov
for Bulgarian Academy of Science and Institute for Balkan Studies

Frontiers in Genetics

doi 10.3389/fgene.2025.1610942

10,566 views
1 citation

Original Research

Published on 22 Sep 2025

Next-generation sequencing of mitochondrial DNA reveals pathogenic variants and protective haplogroup D4 in esophageal cancer

in Cancer Genetics and Oncogenomics

Xiucheng Jiang
Lan Shi
Mei Zhao
Cui Chen
Tao Tang
Simeng Ji
Bingbing Lv
Lihua Jia
Shuhan Duan
Jinyue Ma

Frontiers in Genetics

doi 10.3389/fgene.2025.1643229

2,499 views

16,577 articles

articles

Using buccal methylomic data to create explainable aging clocks as well as classifiers and regressors for lifestyle and demographic factors

Editorial: Genetic dissection and improvement of crop quality and stress adaptation

Prenatal diagnosis and molecular characterization of PKHD1 variants in two Chinese fetuses with Caroli disease/syndrome

Understanding stakeholders’ experience with sickle cell disease by social media listening across Europe

Comparative genome-wide analysis of Ovis aries in Saudi Arabia highlighting inbreeding and genetic isolation of the Najdi sheep breed

Immune-molecular nexus in reproductive disorders: mechanisms linking POI and RSA

LncRNA and mRNA expression characteristic and bioinformatic analysis in anemic diabetic foot ulcers

ZmEXPB7, a β-expansin gene, contributes to drought tolerance in Arabidopsis

CNAdjust: enhancing CNA calling accuracy through systematic baseline adjustment

A partially automated method for DNA extraction from marmoset hair follicles to avoid blood chimerism

Developing prognostic models for cholesterol-related genes linked with immune infiltration in prostate cancer

Association between LRRK2 gene polymorphisms and Parkinson’s disease progression in a Chinese Han population

Functional analysis of MEIS2 splice site variant c.438 + 1G>T in a congenital heart patient

MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma

Concordance of an in-house 2-steps PCR-SSP and nanopore sequencing for HLA-B57:01 and HLA-B58:01 typing: a comparative study

Cross-modal predictive modeling of multi-omic data in 3D airway organ tissue equivalents during viral infection

Identifying metabolism-related genes in liver cancer through weighted gene co-expression network analysis and machine learning

Mechanisms of circular RNAs in diabetic cardiomyopathy: biological characteristics and clinical prospects

Intrauterine phenotype, genetic analysis, and pregnancy follow-up of fetuses with the 16p12.2 microdeletion

Case Report: a family report of hereditary pancreatitis caused by SPINK1 and PRSS1 gene mutations

Constructing a novel mitochondrial-related gene signature for predicting survival and evaluating the tumor immune microenvironment in clear cell renal cell carcinoma

Identification of platelet function-related genes in STEMI patients

Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation

Next-generation sequencing of mitochondrial DNA reveals pathogenic variants and protective haplogroup D4 in esophageal cancer

articles

Using buccal methylomic data to create explainable aging clocks as well as classifiers and regressors for lifestyle and demographic factors

Editorial: Genetic dissection and improvement of crop quality and stress adaptation

Prenatal diagnosis and molecular characterization of PKHD1 variants in two Chinese fetuses with Caroli disease/syndrome

Understanding stakeholders’ experience with sickle cell disease by social media listening across Europe

Comparative genome-wide analysis of Ovis aries in Saudi Arabia highlighting inbreeding and genetic isolation of the Najdi sheep breed

Immune-molecular nexus in reproductive disorders: mechanisms linking POI and RSA

LncRNA and mRNA expression characteristic and bioinformatic analysis in anemic diabetic foot ulcers

ZmEXPB7, a β-expansin gene, contributes to drought tolerance in Arabidopsis

CNAdjust: enhancing CNA calling accuracy through systematic baseline adjustment

A partially automated method for DNA extraction from marmoset hair follicles to avoid blood chimerism

Developing prognostic models for cholesterol-related genes linked with immune infiltration in prostate cancer

Association between LRRK2 gene polymorphisms and Parkinson’s disease progression in a Chinese Han population

Functional analysis of MEIS2 splice site variant c.438 + 1G>T in a congenital heart patient

MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma

Concordance of an in-house 2-steps PCR-SSP and nanopore sequencing for HLA-B*57:01 and HLA-B*58:01 typing: a comparative study

Cross-modal predictive modeling of multi-omic data in 3D airway organ tissue equivalents during viral infection

Identifying metabolism-related genes in liver cancer through weighted gene co-expression network analysis and machine learning

Mechanisms of circular RNAs in diabetic cardiomyopathy: biological characteristics and clinical prospects

Intrauterine phenotype, genetic analysis, and pregnancy follow-up of fetuses with the 16p12.2 microdeletion

Case Report: a family report of hereditary pancreatitis caused by SPINK1 and PRSS1 gene mutations

Constructing a novel mitochondrial-related gene signature for predicting survival and evaluating the tumor immune microenvironment in clear cell renal cell carcinoma

Identification of platelet function-related genes in STEMI patients

Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation

Next-generation sequencing of mitochondrial DNA reveals pathogenic variants and protective haplogroup D4 in esophageal cancer

Concordance of an in-house 2-steps PCR-SSP and nanopore sequencing for HLA-B57:01 and HLA-B58:01 typing: a comparative study