Frontiers in Genetics | Applied Genetic Epidemiology

Original Research

Published on 15 May 2025

Integrated transcriptomic analysis of COVID-19 stages and recovery: insights into key gene signatures, immune features, and diagnostic biomarkers through machine learning

in Applied Genetic Epidemiology

Zhiyuan Gong
He An

Frontiers in Genetics

doi 10.3389/fgene.2025.1599867

186 views

Original Research

Accepted on 14 May 2025

Highly multiplex molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole genome sequencing assessments for selection and relatedness

in Applied Genetic Epidemiology

Karamoko Niaré
Rebecca Crudale
Abebe Fola
Neeva Wernsman Young
Victor Asua
Melissa Conrad
Pierre Gashema
Anita Ghansah
Stan Hangi
Deus S Ishengoma

Frontiers in Genetics

doi 10.3389/fgene.2025.1526049

Original Research

Published on 14 May 2025

EGFR polymorphisms drive lung cancer risk and survival disparities: a genotype-expression-outcome cohort study

in Applied Genetic Epidemiology

Chao Zuo
Ziqiang Wang
Yi Liu
Jing Cheng
Dongli Yang
Yu Wang
Yongchao Qiao

Frontiers in Genetics

doi 10.3389/fgene.2025.1591539

282 views

Original Research

Accepted on 12 May 2025

Global, Regional, and National Burden of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency from 1990 to 2021: A Systematic Analysis of the Global Burden of Disease Study 2021

in Applied Genetic Epidemiology

Zhengyu Yu
Qiang Xioing
Zhongwang Wang
Linfeng Li
Ting Niu

Frontiers in Genetics

doi 10.3389/fgene.2025.1593728

143 views

Original Research

Published on 09 May 2025

Nonmetastatic cell 1 gene polymorphisms are associated with the clinical progression and prognoses of patients with colorectal cancer

in Applied Genetic Epidemiology

Yabin Liu
Tianliang Bai
Zhenxi Zhang
Yanjun Xu
Dexian Kong

Frontiers in Genetics

doi 10.3389/fgene.2025.1485855

295 views

Original Research

Accepted on 07 May 2025

Genetic Association of ACE2 rs2285666 (C>T) and rs2106809 (A>G) and susceptibility to SARS-CoV-2 infection among the Ghanaian population.

in Applied Genetic Epidemiology

Alexander Owusu Boakye
Christian Obirikorang
Anthony Afum-Adjei Awuah
Evans Asamoah Adu
Doris Winter
Eric Ebenezer Boham
Hakim Alani
Sylvester Kofi Newton
Nana Safi Toure Almoustapha
James Deke

Frontiers in Genetics

doi 10.3389/fgene.2025.1555515

Original Research

Accepted on 02 May 2025

The Role of E2F1 in Promoting EIF4EBP1 Transcription in Cryptorchid Mice: Association with Autophagy in Germ Cells

in Applied Genetic Epidemiology

Jianguo Zhang
Yanhui Liu
Hailong Zhang
Lin Yang
Danjing Sun
Lili Xiao
Xiaoyun Wang
Xiangming Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1536672

Original Research

Published on 01 May 2025

Development and validation of a polygenic risk score for height in a Greek cohort: Association with blood pressure measurements

in Applied Genetic Epidemiology

Ioanna Panagiota Kalafati
Margaritis Tsifintaris
Maria Dimitriou
Effimia Grigoriou
Panagiotis Moulos
George V. Dedoussis

Frontiers in Genetics

doi 10.3389/fgene.2025.1538975

483 views

Original Research

Published on 15 Apr 2025

Multi-trait GWAS identifies pleiotropic loci associated with colorectal cancer in East Asian populations

in Applied Genetic Epidemiology

Xiqi Chen
Yong Zhu
Peng Zhong
Guangdong Xie

Frontiers in Genetics

doi 10.3389/fgene.2025.1590652

883 views

Data Report

Published on 26 Mar 2025

Adaptation of key bacterial vaginosis-associated bacteria to a medium simulating genital tract secretions: a transcriptomic analysis

in Applied Genetic Epidemiology

Lúcia G. V. Sousa
Angela França
Vânia Pinheiro
Christina A. Muzny
Nuno Cerca

Frontiers in Genetics

doi 10.3389/fgene.2025.1552307

1,023 views

Original Research

Published on 25 Mar 2025

Genetic analysis reveals the shared genetic architecture between breast cancer and atrial fibrillation

in Applied Genetic Epidemiology

Yang Yang
Jiayi Chen
XiaoHua Zhao
Fuhong Gong
Ruimin Liu
Jingge Miao
Mengping Lin
Fei Ge
Wenlin Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1450259

1,589 views

Review

Published on 11 Mar 2025

Bibliometric analysis of case-control studies on the association between HLA alleles and multiple sclerosis in adults

in Applied Genetic Epidemiology

Enola Maer
Marjorie Maya Hubacher
Livia Livint Popa
Dana Marieta Fodor
Razvan Mircea Chereches
Dafin F. Muresanu
Vitalie Vacaras
Maria Chiriac
Horea Vladi Matei
Nicu Catalin Draghici

Frontiers in Genetics

doi 10.3389/fgene.2025.1524360

982 views

Brief Research Report

Published on 11 Mar 2025

Retrospective chart review of inherited and idiopathic dystonia

in Applied Genetic Epidemiology

A. Alakkas
H. Shinawi
J. A. Bajwa
O. Alsinaidi
A. Al-Hashim

Frontiers in Genetics

doi 10.3389/fgene.2025.1504744

802 views

Review

Published on 05 Mar 2025

Sex differences in asthma: omics evidence and future directions

in Applied Genetic Epidemiology

Bichen Peng
Weiyi Ye
Shuai Liu
Yue Jiang
Ziang Meng
Miao Guo
Lili Zhi
Xiao Chang
Lei Shao

Frontiers in Genetics

doi 10.3389/fgene.2025.1560276

1,466 views

Original Research

Published on 05 Mar 2025

Identification of four key genes related to the diagnosis of chronic obstructive pulmonary disease using bioinformatics analysis

in Applied Genetic Epidemiology

Jinxia Li
Xiuming Liu
Yonghu Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1499996

1,023 views

Editorial

Published on 19 Feb 2025

Editorial: Advancements and prospects of genome-wide association studies

in Applied Genetic Epidemiology

Ayo P. Doumatey
Yafang Li
Juan Carlos Fernandez-Lopez

Frontiers in Genetics

doi 10.3389/fgene.2025.1564006

1,136 views