Frontiers in Genetics | Applied Genetic Epidemiology

Original Research

Published on 09 Sep 2026

Genomic analysis identifies candidate supergene architecture for host-feeding behavior in wild Aedes aegypti dengue vector mosquitoes

in Applied Genetic Epidemiology

Devojit Kumar Sarma
Sudeesh Warkare
Sweta Mishra
Deepanker Das
Lokendra Rathod
Manoj Kumawat
Siddharth Singh Tomar
Samradhi Singh
Manoj Kumar
Rajnarayan R. Tiwari

Frontiers in Genetics

doi 10.3389/fgene.2026.1910877

371 views

Original Research

Published on 28 Aug 2026

Gene by environment interaction effects on the metabolic subtype of Polycystic Ovary Syndrome in Hispanic Community Health Study/Study of Latinos

in Applied Genetic Epidemiology

Hridya R. Gardner
Michelle L. Meyer
Jennifer K. Wagner
Krista M. Perreira
Laura Y. Zhou
Martha Daviglus
Christina Cordero
Anne E. Justice
Lindsay Fernandez-Rhodes

Frontiers in Genetics

doi 10.3389/fgene.2026.1801152

777 views

Correction

Published on 03 Aug 2026

Correction: Enhancing glaucoma prediction across ancestries: integrating functional annotation into multi-trait polygenic risk scores

in Applied Genetic Epidemiology

Xiaoyi Raymond Gao

Frontiers in Genetics

doi 10.3389/fgene.2026.1942473

610 views

Review

Published on 17 Jul 2026

Genomic approaches to understanding pregnancy phenotypes and birth outcomes and their links with long-term maternal and offspring health—the value of distinguishing maternal and fetal genetic effects

in Applied Genetic Epidemiology

Ge Zhang
Rachel M. Freathy
Bo Jacobsson
Deborah A. Lawlor

Frontiers in Genetics

doi 10.3389/fgene.2026.1766185

1,485 views

Original Research

Published on 15 Jul 2026

Bidirectional association between zinc and liver cirrhosis: evidence from mendelian randomization and clinical validation

in Applied Genetic Epidemiology

Liu-dan Liang
Ying Yang
Qi-wen Huang
Chen-yi Huang
Bing-fang Lu
Jian-nan Lv
Wei Wei
Ying Li
Hao Wang
Hong-ling Yuan

Frontiers in Genetics

doi 10.3389/fgene.2026.1833546

1,074 views

Correction

Published on 15 Jul 2026

Correction: Distribution of CYP2C19 genetic polymorphisms and pharmacogenomic implications in 11,710 patients with cardiovascular and cerebrovascular conditions: a large population-based study in eastern China

in Applied Genetic Epidemiology

Minfei Peng
Minmin He
Ying Chen
Xiaoli Zhu
Jun Li

Frontiers in Genetics

doi 10.3389/fgene.2026.1925477

699 views

Original Research

Published on 13 Jul 2026

Community awareness of genetic disorders associated with consanguineous marriage and acceptance of preventive screening, a cross-sectional study from Saudi Arabia

in Applied Genetic Epidemiology

Abdulmajeed A. A. Sindi
Uthman Albakri
Sarah A. Alzahrani
Haneen M. Alqarni
Rimiyyah K. Alzahrani
Batol M. Albanghali
Mohammed A. Shanawaz
Basim A. Othman
Dhuha F. Alghamdi
Aryam A. Alghamdi

Frontiers in Genetics

doi 10.3389/fgene.2026.1866894

990 views

Original Research

Published on 02 Jul 2026

Disease-predominant loci across Alzheimer’s disease, Parkinson’s disease and Lewy body dementia: evidence from the UK Biobank prospective cohort, conditional GWAS and colocalization

in Applied Genetic Epidemiology

Ying Zhang
Zhishuai Zhang
Shizheng Qiu
Yang Hu

Frontiers in Genetics

doi 10.3389/fgene.2026.1865257

2,140 views

Original Research

Published on 29 Jun 2026

Distribution of CYP2C19 genetic polymorphisms and pharmacogenomic implications in 11,710 patients with cardiovascular and cerebrovascular conditions: a large population-based study in eastern China

in Applied Genetic Epidemiology

Minfei Peng
Minmin He
Ying Chen
Xiaoli Zhu
Jun Li

Frontiers in Genetics

doi 10.3389/fgene.2026.1830873

1,445 views

Mini Review

Published on 25 Jun 2026

Genetic susceptibility shaped by biological state: beyond gene-environment interaction

in Applied Genetic Epidemiology

Hui-Qi Qu
Hakon Hakonarson

Frontiers in Genetics

doi 10.3389/fgene.2026.1877629

1,491 views

Original Research

Published on 16 Jun 2026

Age-associated clinical characteristics and ATP7B mutation landscape in pediatric Wilson’s disease: a study from southwest China

in Applied Genetic Epidemiology

Tingting Wu
Yuanzhen Zhang
Xiaorong Peng
Yunnan Chang
Tao Qin
Jing Zhu
Qiqin Tang
Jiao Tian
Ruiqiu Zhao
Hongmei Xu

Frontiers in Genetics

doi 10.3389/fgene.2026.1839993

1,553 views

Brief Research Report

Published on 03 Jun 2026

Temporal trends in artemisinin partial resistance and other antimalarial drug mutations in Plasmodium falciparum from Kagera region, Northwestern Tanzania, 2021–2023

in Applied Genetic Epidemiology

Alfred Simkin
Salehe S. Mandai
Abebe A. Fola
Neeva Wernsman Young
Jacob Marglous
Dativa Pereus
Catherine Bakari
Rashid A. Madebe
Misago D. Seth
Rule B. Mrengela

Frontiers in Genetics

doi 10.3389/fgene.2026.1776108

1,984 views

Original Research

Published on 02 Jun 2026

Molecular characterization of a rare heterozygous APOA5 variant in a Chinese family with moderate hypertriglyceridemia

in Applied Genetic Epidemiology

Hongxia Liu
Xiao Yuan
Jie Wang
Yuande Mao
Jinxi Wang
Dongli Wang
Fang Tian
Yili Yang
Bo Xiang

Frontiers in Genetics

doi 10.3389/fgene.2026.1796970

1,546 views

Original Research

Published on 26 May 2026

Multimodal evidence for the association between muscle mass and NAFLD: insights from hospital-based data, NHANES and mendelian randomization

in Applied Genetic Epidemiology

Weidong Xie
Sen Li
Shaoliang Han

Frontiers in Genetics

doi 10.3389/fgene.2026.1821445

1,730 views

Original Research

Published on 21 May 2026

Causal association and molecular mechanisms of periodontal disease and muscle wasting and atrophy: Mendelian randomization and bioinformatics analysis

in Applied Genetic Epidemiology

Yaxuan Liu
Wenjuan Zhang
Yang Liu
Yuting Bian
Xin Liu
Wei Liu

Frontiers in Genetics

doi 10.3389/fgene.2026.1810047

1,758 views

Data Report

Published on 19 May 2026

Nanopore genome sequencing of Aeromonas salmonicida strain AB001 from lesions of diseased Acipenser baerii

in Applied Genetic Epidemiology

Akzhigit Mashzhan
Izat Smekenov
Serik Bakiyev
Kalamkas Utegenova
Aigerim Kuanbay
Ulykbek Kairov
Amangeldy Bissenbaev

Frontiers in Genetics

doi 10.3389/fgene.2026.1816465

1,451 views

Original Research

Published on 07 May 2026

Enhancing glaucoma prediction across ancestries: integrating functional annotation into multi-trait polygenic risk scores

in Applied Genetic Epidemiology

Xiaoyi Raymond Gao

Frontiers in Genetics

doi 10.3389/fgene.2026.1842316

1,716 views
1 citation

Original Research

Published on 29 Apr 2026

Genetics-guided screening and biological validation identify zeylenol as a promising EGFR inhibitor in glioma

in Applied Genetic Epidemiology

Lin Pan
Yifan Li
Leyan Chen
Wenzhuo Yang
Haiqin Gao
Yuxin Hou
Shengxuan Liu
Zibing Zhao
Xinhui Wang
Hongyu Chen

Frontiers in Genetics

doi 10.3389/fgene.2026.1822595

1,645 views

Original Research

Published on 29 Apr 2026

Genetic metrics decode Plasmodium falciparum diversity: complexity of infection, parasite connectivity, and transmission intensity in Mainland Tanzania’s diverse regions

in Applied Genetic Epidemiology

Dativa Pereus
Abebe A. Fola
Catherine Bakari
Misago D. Seth
Rebecca DeFeo
Beatus M. Lyimo
Celine I. Mandara
Rashid A. Madebe
Doris Mbata
Zachary R. Popkin-Hall

Frontiers in Genetics

doi 10.3389/fgene.2026.1695073

2,266 views
2 citations

Original Research

Published on 24 Apr 2026

Causal effects of maternal BMI on pregnancy outcomes: a Mendelian randomisation study investigating the mediating role of blood counts

in Applied Genetic Epidemiology

Christopher Flatley
Geng Wang
Alesha Hatton
Kym-Mai Nguyen
Liang-Dar Hwang
Nicole M. Warrington

Frontiers in Genetics

doi 10.3389/fgene.2026.1697926

1,733 views

Correction

Published on 09 Apr 2026

Correction: Whole-exome sequencing analysis of human semen quality in Russian multiethnic population

in Applied Genetic Epidemiology

Semyon Kolmykov
Gennady Vasiliev
Ludmila Osadchuk
Maxim Kleschev
Alexander Osadchuk

Frontiers in Genetics

doi 10.3389/fgene.2026.1837698

1,379 views

Systematic Review

Published on 19 Mar 2026

Causal risk and protective factors for rheumatoid arthritis: a comprehensive mendelian randomization systematic review and meta-analysis

in Applied Genetic Epidemiology

Xu Han
Zhenzhen Han
Siyu Wang
Yafei Zhang
Ying Liu
Jing Zhang
Jinlong Yu
Danyang Cui
Xiaoxia Ma
Jiazhu Jin

Frontiers in Genetics

doi 10.3389/fgene.2026.1774582

2,874 views

General Commentary

Published on 18 Mar 2026

Commentary: “TRIB3 promoter 33 bp VNTR is associated with the risk of cerebrovascular disease in type 2 diabetic patients”

in Applied Genetic Epidemiology

Benedetta Torbidoni-Baldassari
Lucrezia Romagnoli
Valerio Napolioni

Frontiers in Genetics

doi 10.3389/fgene.2026.1802422

1,694 views

Review

Published on 25 Feb 2026

Unravelling the genetic architecture of cardiovascular disease through structural variant detection with whole-genome sequencing

in Applied Genetic Epidemiology

Dona N. P. Colombage
Eric K. Moses
Phillip E. Melton

Frontiers in Genetics

doi 10.3389/fgene.2026.1747711

2,377 views

476 articles

articles

Genomic analysis identifies candidate supergene architecture for host-feeding behavior in wild Aedes aegypti dengue vector mosquitoes

Gene by environment interaction effects on the metabolic subtype of Polycystic Ovary Syndrome in Hispanic Community Health Study/Study of Latinos

Correction: Enhancing glaucoma prediction across ancestries: integrating functional annotation into multi-trait polygenic risk scores

Genomic approaches to understanding pregnancy phenotypes and birth outcomes and their links with long-term maternal and offspring health—the value of distinguishing maternal and fetal genetic effects

Bidirectional association between zinc and liver cirrhosis: evidence from mendelian randomization and clinical validation

Correction: Distribution of CYP2C19 genetic polymorphisms and pharmacogenomic implications in 11,710 patients with cardiovascular and cerebrovascular conditions: a large population-based study in eastern China

Community awareness of genetic disorders associated with consanguineous marriage and acceptance of preventive screening, a cross-sectional study from Saudi Arabia

Disease-predominant loci across Alzheimer’s disease, Parkinson’s disease and Lewy body dementia: evidence from the UK Biobank prospective cohort, conditional GWAS and colocalization

Distribution of CYP2C19 genetic polymorphisms and pharmacogenomic implications in 11,710 patients with cardiovascular and cerebrovascular conditions: a large population-based study in eastern China

Genetic susceptibility shaped by biological state: beyond gene-environment interaction

Age-associated clinical characteristics and ATP7B mutation landscape in pediatric Wilson’s disease: a study from southwest China

Temporal trends in artemisinin partial resistance and other antimalarial drug mutations in Plasmodium falciparum from Kagera region, Northwestern Tanzania, 2021–2023

Molecular characterization of a rare heterozygous APOA5 variant in a Chinese family with moderate hypertriglyceridemia

Multimodal evidence for the association between muscle mass and NAFLD: insights from hospital-based data, NHANES and mendelian randomization

Causal association and molecular mechanisms of periodontal disease and muscle wasting and atrophy: Mendelian randomization and bioinformatics analysis

Nanopore genome sequencing of Aeromonas salmonicida strain AB001 from lesions of diseased Acipenser baerii

Enhancing glaucoma prediction across ancestries: integrating functional annotation into multi-trait polygenic risk scores

Genetics-guided screening and biological validation identify zeylenol as a promising EGFR inhibitor in glioma

Genetic metrics decode Plasmodium falciparum diversity: complexity of infection, parasite connectivity, and transmission intensity in Mainland Tanzania’s diverse regions

Causal effects of maternal BMI on pregnancy outcomes: a Mendelian randomisation study investigating the mediating role of blood counts

Correction: Whole-exome sequencing analysis of human semen quality in Russian multiethnic population

Causal risk and protective factors for rheumatoid arthritis: a comprehensive mendelian randomization systematic review and meta-analysis

Commentary: “TRIB3 promoter 33 bp VNTR is associated with the risk of cerebrovascular disease in type 2 diabetic patients”

Unravelling the genetic architecture of cardiovascular disease through structural variant detection with whole-genome sequencing