CORRECTION article

Front. Immunol., 16 November 2018

Sec. Immunological Tolerance and Regulation

Volume 9 - 2018 | https://doi.org/10.3389/fimmu.2018.02627

Corrigendum: Lymphocyte Autophagy in Homeostasis, Activation, and Inflammatory Diseases

  • 1. CNRS UPR3572, Immunology, Immunopathology and Therapeutic Chemistry/Laboratory of Excellence MEDALIS, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France

  • 2. University of Strasbourg, Strasbourg, France

In the original article, two clarifications about cited references are necessary.

First, the sentence “As a consequence, autophagy-deficient T cells show impaired TH9 differentiation and antitumor responses (63)” should be “As a consequence, autophagy-deficient T cells show enhanced TH9-dependent anti-tumor responses (63)”. A correction has been made to the section Autophagy in Peripheral T Cells, Macroautophagy in T Cell Activation, paragraph 2.

Moreover, even if mechanisms are not totally understood, Chen et al. indeed found experimental evidence in [42], for a role played by autophagy in limiting lipid peroxidation toxicity induced by reactive oxygen species. The sentence “To date, no mechanism linking autophagy and memory B cell survival has been proposed. It is possible that mitophagy and mobilization of lipids through lipophagy might be important, as for T cells” has been corrected to “Chen et al. (42) showed that autophagy in memory B cells limits mitochondrial ROS production and toxicity of peroxidized lipids. It is also possible that mobilization of lipids through lipophagy might be required for the survival of both memory B and T cells”. A correction has been made to the section Autophagy in peripheral B Cells, Macroautophagy in Memory B Cell and Plasma Cell Survival, paragraph 2.

The authors apologize for these errors and state that they do not change the scientific conclusions of the article in any way. The original article has been updated.

Statements

Conflict of interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

  • 42.

    ChenMHongMJSunHWangLShiXGilbertBEet al. Essential role for autophagy in the maintenance of immunological memory against influenza infection. Nat Med. (2014) 20:50310. 10.1038/nm.3521

  • 63.

    RiveraVargas TCaiZShenYDossetMBenoit-LizonIMartinTet al. Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells. Nat Commun. (2017) 8:559. 10.1038/s41467-017-00468-w

Summary

Keywords

autophagy, mitophagy, metabolism, unfolded protein response, autoimmunity, lymphocytes

Citation

Arbogast F and Gros F (2018) Corrigendum: Lymphocyte Autophagy in Homeostasis, Activation, and Inflammatory Diseases. Front. Immunol. 9:2627. doi: 10.3389/fimmu.2018.02627

Received

24 August 2018

Accepted

25 October 2018

Published

16 November 2018

Volume

9 - 2018

Edited and reviewed by

Marko Radic, University of Tennessee College of Medicine, United States

Updates

Copyright

*Correspondence: Frédéric Gros

This article was submitted to Immunological Tolerance and Regulation, a section of the journal Frontiers in Immunology

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Outline

Cite article

Copy to clipboard


Export citation file


Share article

Article metrics