CORRECTION article

Front. Immunol., 15 December 2021

Sec. Inflammation

Volume 12 - 2021 | https://doi.org/10.3389/fimmu.2021.738591

Corrigendum: A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction

  • 1. Division of Cardiology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan

  • 2. Institute of Microbiology and Immunology, National Yang-Ming University, Taipei, Taiwan

  • 3. Department of Chemistry, National University of Singapore, Singapore, Singapore

  • 4. Department of Laboratory Medicine, Linsen, Chinese Medicine and Kunming Branch, Taipei City Hospital, Taipei, Taiwan

  • 5. Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan

  • 6. Department of Biotechnology and Animal Science, National Ilan University, Ilan, Taiwan

  • 7. Division of Wood Cellulose, Taiwan Forestry Research Institute, Taipei, Taiwan

  • 8. G.B. Elyakov Pacific Institute of Bioorganic Chemistry FEB RAS, Vladivostok, Russia

  • 9. Department of Biological Science & Technology, National Chiao Tung University, Hsinchu, Taiwan

  • 10. Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan

In the original article, there was a mistake in Figures 5E and 8E as published. We found a mismatch between the Western blot images (p-JNK1/2) in comparison to the labeling in Figures 5E. Regarding the effect of F240B on LPS-induced phosphorylation of ERK1/2, p38 and JNK1/2, we tested two time-course studies: (A) condition was LPS treatment for 0, 10, 20, 30 min (total eight groups), (A) condition was LPS treatment for 0, 10, 20, 30, 60 min (total ten groups). In the Figures 5E of the original manuscript, we used (A) condition for ERK1/2, p38; however, we used (B) condition for JNK. In addition, in Figures 8E of the original manuscript, the Western blot image of input NLRP3 included a non-specific band (far left band), making it looks like a mismatch between input NLRP3 and input PKR. The corrected Figures 5E and 8E appear below.

Figure 5

Figure 8

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher’s Note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Summary

Keywords

NLRP3 inflammasome, conjugated polyenes, autophagy, mitochondria, peritonitis

Citation

Wu C-H, Gan CH, Li L-H, Chang J-C, Chen S-T, Menon MP, Cheng S-M, Yang S-P, Ho C-L, Chernikov OV, Lin C-H, Lam Y and Hua K-F (2021) Corrigendum: A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction. Front. Immunol. 12:738591. doi: 10.3389/fimmu.2021.738591

Received

09 July 2021

Accepted

20 October 2021

Published

15 December 2021

Volume

12 - 2021

Edited and reviewed by

Massimo Collino, University of Turin, Italy

Updates

Copyright

*Correspondence: Kuo-Feng Hua, ; Yulin Lam,

This article was submitted to Inflammation, a section of the journal Frontiers in Immunology

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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