Corrigendum: Investigation of the association between the genetic polymorphisms of co-stimulatory system and systemic lupus erythematosus

In the published article, there was an error. The TNFSF4 gene is reverse, in which the wild-type allele of rs1234314 is C rather than G and the wild-type allele of rs45454293 is C rather than G. Originally, the direction of the primer was wrong, so the allele on the sequence we read was followed by the error. Because the complementary base of C is G and rs45454293 is exactly C to G mutation, we didn’t find this error at that time. This mistake will cause the opposite result, leading to a misunderstanding about risk allele for SLE. Thus, there are 5 errors in the original manuscript needed to be corrected.

1. A correction has been made to the Abstract.

This sentence previously stated: “GG vs. CC: p=0.004; GG+ CG vs. CC: p=0.001”

The corrected sentence appears below: “CC vs. GG: p=0.004; CC+ CG vs. GG: p=0.001”.

2. A correction has been made to Results, The analysis of genotype frequencies.

This sentence previously stated: “Compared to the GG genotype, the subjects with the CC genotype would have a 4.4 times risk of SLE (95% CI =1.577-12.275, p = 0.004), which also had significance based on the dominant model (GG+CG vs. CC: OR = 4.362, 95% CI = 1.727-11.015, p = 0.001)”.

The corrected sentence appears below: “Compared to the CC genotype, the subjects with the GG genotype would have a 4.4 times risk of SLE (95% CI =1.577-12.275, p = 0.004), which also had significance based on the dominant model (CC+CG vs. GG: OR = 4.362, 95% CI = 1.727-11.015, p = 0.001)”.

3. A correction has been made to Discussion, paragraph 3. This sentence previously stated:

“It was shown that the CC genotype of rs1234314 provided a protective effect against allergic rhinitis (50), which was contrary to our result”.

The corrected sentence appears below:

“It was shown that the CC genotype of rs1234314 provided a protective effect against allergic rhinitis (50), which was the same as our result”.

4. In the published article, there was an error in Table 2 as published. The “SNP” and “Allele” columns of the TNFSF4 gene section previously contained the values “rs1234314 C/G and rs45454293 A/G” when they should contain the values “rs1234314 G/C and rs45454293 C/T”. The corrected Table 2 and its caption appears below.

5. In the published article, there was an error in Table 3 as published. The “Genotype” column of the TNFSF4 gene section had “GG” and “CC” in the wrong positions. The corrected Table 3 and its caption appears below.

6. In the published article, there was an error in Table 4 as published. The last row of the “Haplotypes” column previously contained “G”s instead of “C”s.

The corrected Table 4 and its caption appears below.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Statements

Summary

Keywords

systemic lupus erythematosus (SLE), co-stimulatory/co-inhibitory molecules, single nucleotide polymorphism (SNP), autoimmune disease (AD), association

Citation

Chen D-P, Lin W-T and Yu K-H (2023) Corrigendum: Investigation of the association between the genetic polymorphisms of co-stimulatory system and systemic lupus erythematosus. Front. Immunol. 13:1113152. doi: 10.3389/fimmu.2022.1113152

Received

01 December 2022

Accepted

07 December 2022

Published

16 January 2023

Volume

13 - 2022

Edited and reviewed by

Zhiwei Xu, The University of Queensland, Australia

Updates

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Copyright

© 2023 Chen, Lin and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Kuang-Hui Yu, gout@adm.cgmh.org.tw

This article was submitted to Autoimmune and Autoinflammatory Disorders: Autoimmune Disorders, a section of the journal Frontiers in Immunology

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