CORRECTION article

Front. Immunol., 22 April 2024

Sec. Molecular Innate Immunity

Volume 15 - 2024 | https://doi.org/10.3389/fimmu.2024.1395642

Corrigendum: Sulforaphane diminishes moonlighting of pyruvate kinase M2 and interleukin 1β expression in M1 (LPS) macrophages

  • 1. Department of Pharmaceutical Sciences, University of Vienna, Vienna, Austria

  • 2. Vienna Doctoral School of Pharmaceutical, Nutritional and Sport Sciences (VDS PhaNuSpo), University of Vienna, Vienna, Austria

  • 3. Vienna Metabolomics Center (VIME), University of Vienna, Vienna, Austria

  • 4. College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China

  • 5. Molecular Systems Biology (MOSYS), Department of Functional and Evolutionary Ecology, University of Vienna, Vienna, Austria

In the published article, there was an error in the legend for Figure 7, panel B as published. The labeling of the lanes in the immunoblots was incorrect.

Figure 7

The corrected legend appears below.

“Sfn does not affect Y105 phosphorylation but glutathionylation of PKM2 in M1 (LPS) macrophages. iBMDM were pretreated with DMSO or the indicated concentrations of Sfn for 30 min prior to stimulation with LPS for 6 h. (A) Total cell lysates were immunoblotted for p(Y105), total PKM2, and actin as a loading control. Representative blots of at least three independent experiments are depicted. Bar graphs represent compiled densitometric data. (B) Macrophages were pretreated with Sfn (10 µM) or the GSH donor glutathione-ethylester (GSEE) before LPS was added for another 6 h. Proteins were harvested under nonreducing conditions. Lysates (input) or immunoprecipitates obtained with an antibody specific for protein-bound glutathione (GSS-X) were subjected to immunoblot analysis for PKM2. Representative blots of three independent experiments with consistent results are depicted.”

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

In the published article, there was an error in Figure 7, panel B as published. The labeling of the lanes in the immunoblots was incorrect. The corrected Figure 7 appears below.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Statements

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Summary

Keywords

sulforaphane, macrophages, M1 polarization, glycolysis, PKM2, interleukin 1 beta

Citation

Bahiraii S, Brenner M, Yan F, Weckwerth W and Heiss EH (2024) Corrigendum: Sulforaphane diminishes moonlighting of pyruvate kinase M2 and interleukin 1β expression in M1 (LPS) macrophages. Front. Immunol. 15:1395642. doi: 10.3389/fimmu.2024.1395642

Received

04 March 2024

Accepted

09 April 2024

Published

22 April 2024

Volume

15 - 2024

Edited and reviewed by

Francesca Granucci, University of Milano-Bicocca, Italy

Updates

Copyright

*Correspondence: Elke H. Heiss,

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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