ORIGINAL RESEARCH article
Front. Immunol., 16 December 2024
Sec. Inflammation
Volume 15 - 2024 | https://doi.org/10.3389/fimmu.2024.1410904
Fexuprazan safeguards the esophagus from hydrochloric acid-induced damage by suppressing NLRP1/Caspase-1/GSDMD pyroptotic pathway
Seo Yeon Kim 1,2
Jung-Ho Yoon 1
Da Hyun Jung 1
Ga Hee Kim 1
Chul Hoon Kim 2,3
Sang Kil Lee 1*
1. Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Republic of Korea
2. Department of Internal Medicine, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea
3. Department of Pharmacology, BK21 PLUS Project for Medical Science, Brain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea
Summary
Citation
Kim SY, Yoon J-H, Jung DH, Kim GH, Kim CH and Lee SK (2024) Fexuprazan safeguards the esophagus from hydrochloric acid-induced damage by suppressing NLRP1/Caspase-1/GSDMD pyroptotic pathway. Front. Immunol. 15:1410904. doi: 10.3389/fimmu.2024.1410904
Received
02 April 2024
Accepted
22 November 2024
Published
16 December 2024
Volume
15 - 2024
Edited by
Yolanda López-Vidal, National Autonomous University of Mexico, Mexico
Reviewed by
Vasile Valeriu Lupu, Grigore T. Popa University of Medicine and Pharmacy, Romania
Gwang Ha Kim, Pusan National University, Republic of Korea
Updates
Disclaimer
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