ORIGINAL RESEARCH article

Front. Immunol.

Sec. Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1548788

The L-shaped association between weight-adjusted-waist index and all-cause mortality in individuals with psoriasis: results from NHANES database retrospective cohort study

Provisionally accepted
Jiawen  ChenJiawen ChenXueting  ZengXueting ZengNiu  XiangNiu XiangRenwei  LuoRenwei LuoZhixun  XiaoZhixun XiaoRongying  ChenRongying ChenBeiqi  LinBeiqi LinHui  KeHui KeTing  GongTing GongChao  JiChao Ji*
  • Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350005, People's Republic of China., Fuzhou, China

The final, formatted version of the article will be published soon.

Background: While obesity is widely recognized as a robust risk factor contributing to both the onset and exacerbation of psoriasis-a chronic, immune-mediated skin disorderthe relationship between the Weight-Adjusted-Waist Index (WWI), an emerging metric for the nuanced evaluation of obesity, and mortality rates specifically within the psoriatic population is uncharted territory in current medical academic research. This study investigated the associations of WWI with all-cause mortality among American individuals with psoriasis.

Keywords: Weight-Adjusted-Waist Indexs, All-cause mortality, Psoriasis, Obesity, L-shaped associations

Received: 20 Dec 2024; Accepted: 05 Jun 2025.

Copyright: © 2025 Chen, Zeng, Xiang, Luo, Xiao, Chen, Lin, Ke, Gong and Ji. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Chao Ji, Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350005, People's Republic of China., Fuzhou, China

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