In the published article, there was an error in Figure 3 as published. In the Figure 3C, the image of the non-permeabilized AdHu5-PfCSP is a duplicate of the non-permeabilized AAV1-PfCSP-G(+) image. The corrected Figure 3 and its caption appear below.
Figure 3
Functional activity of AAV1-PfCSP-G(+). (A) Constructs of AAV1-PfCSP-G(+) and AdHu5-PfCSP-G(+). Expression of the pcsp gene cassette in AAV1 and AdHu5 was driven by a CMV promoter and CAG promoter, respectively. G, VSV-G. (B) Expression of PfCSP in HEK293T cells transduced with AdHu5-PfCSP (lane 1, MOI = 3), AAV1-PfCSP-G(–) (lane 2, MOI = 105), or AAV1-PfCSP-G(+) (lane 3, MOI = 105), as assessed by immunoblotting with mAb 2A10 at 48 h post-transduction. (C) Localization of PfCSP expression in HEK293T cells transduced with AAV1-PfCSP-G(+) (MOI = 105) and AdHu5-PfCSP (MOI = 10), as determined by IFA conducted as described in Figure 2C. (D) Anti-PfCSP IgG antibody responses. Groups of BALB/c mice (n = 10) were immunized with the indicated regimen at a 6-week interval. At 4 weeks post-boost, serum samples were collected from each mouse, and their anti-PfCSP IgG titers were determined by ELISA. AdHu5-PfCSP, AAV1-PfCSP-G(–), and AAV1-PfCSP (G+) are shown as AdHu5, AAV1-G(–), and AAV1-G(+), respectively. Bars and error bars indicate the means and SD of the values, respectively. Between-group differences were assessed with a Mann–Whitney U-test (*p < 0.05).
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Publisher’s note
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Summary
Keywords
Plasmodium falciparum circumsporozoite protein, Pfs25, human adenovirus serotype 5, adeno-associated virus, malaria vaccine, transmission-blocking
Citation
Yusuf Y, Yoshii T, Iyori M, Yoshida K, Mizukami H, Fukumoto S, Yamamoto DS, Alam A, Emran TB, Amelia F, Islam A, Otsuka H, Takashima E, Tsuboi T and Yoshida S (2025) Corrigendum: Adeno-associated virus as an effective malaria booster vaccine following adenovirus priming. Front. Immunol. 16:1592118. doi: 10.3389/fimmu.2025.1592118
Received
12 March 2025
Accepted
01 April 2025
Published
28 April 2025
Volume
16 - 2025
Edited and reviewed by
Adrian John Frederick Luty, Institut de Recherche Pour le Développement (IRD), France
Updates
Copyright
© 2025 Yusuf, Yoshii, Iyori, Yoshida, Mizukami, Fukumoto, Yamamoto, Alam, Emran, Amelia, Islam, Otsuka, Takashima, Tsuboi and Yoshida.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Shigeto Yoshida, shigeto@p.kanazawa-u.ac.jp
Disclaimer
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.