EDITORIAL article
Front. Immunol.
Sec. Cancer Immunity and Immunotherapy
Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1628689
This article is part of the Research TopicImmune Cell Therapy Approaches Targeting Tumor MicroenvironmentView all 13 articles
Editorial: Immune Cell Therapy Approaches Targeting Tumor Microenvironment
Provisionally accepted
- Roswell Park Comprehensive Cancer Center, University at Buffalo, Buffalo, United States
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Recent advances in immunotherapy have significantly improved clinical outcomes, particularly for 10 cancers that were once considered untreatable or with poor prognosis. A growing body of evidence 11 underscores the importance of both tumoral and non-tumoral components of the tumor 12 microenvironment (TME) in driving cancer progression. The TME is a dynamic and complex 13 ecosystem that includes not only cancer cells but also stromal cells such as immune cells, endothelial 14 cells, and fibroblasts, as well as extracellular matrix components.
Keywords: Cancer, combination therapy, Immunotherapy, tumor microenvironment 8, Tumor Microenvironment, Immune checkpoint
Received: 14 May 2025; Accepted: 15 May 2025.
Copyright: © 2025 Kalathil and Patnaik. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Suresh Gopi Kalathil, Roswell Park Comprehensive Cancer Center, University at Buffalo, Buffalo, United States
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.