CORRECTION article
Front. Immunol.
Sec. Alloimmunity and Transplantation
Leucocyte dynamics in Cynomolgus monkeys following heterotopic heart allotransplantation under costimulation pathway blockade
Provisionally accepted
- 1University of Maryland, Baltimore, United States
- 2Harvard Medical School, Boston, United States
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The original version of this article has been updated. 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0 2 0 0 0 0 2 0 8 0 0 0 1 1 0 0 0 0 0 0 5 5 15 0 0 0 23 0 0 1 1 3 0 0 17 0 54 0 0 0 0 0 0 1 0 0 0 0 0 1 5 0 0 0 0 0 0 0 0 0 0 0 1 15 12 0 0 0 37 0 0 1 0 2 0 0 2 1 5 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 3 2 0 0 0 2 0 0 0 0 0 0 0 10 1 1 0 0 0 0 0 0 0 0 0 0 0 2 2 9 0 0 0 1 0 0 0 0 0 0 0 3 0 20 0 0 0 49 0 0 0 0 3 0 0 1 0 8 1 0 0 0 0 0 1 0 0 0 0 2 2 8 0 0 0 0 0 0 0 0 0 0 0 0 7 38 0 0 0 27 0 0 0 0 3 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 3 2 0 0 0 1 0 0 0 0 0 0 1 0 6 0 0 0 2 0 0 1 0 22 0 0 2 0 1 0 0 0 0 0 0 0 0 0 0 1 17 2 14 6 0 0 0 0 0 0 0 0 0 0 3 27 47 0 0 0 25 0 0 8 1 3 0 1 105 8 22 0 0 0 1 0 1 6 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 1 14 0 0 0 29 0 0 0 0 2 0 0 3 0 3 0 0 0 0 0 0 0 0 0 0 Last Name author1 et al. There was a mistake in the caption of table 4 as published. Some numbers are wrong: …5-replace with 8; eight-replace with 6; 1 replace with 3; 2.7replace with 1; Some abbreviations were misplaced: … blood-replace with PB; add "PB or" in front of LNs.For each monkey (rows) for each corresponding sample, flow cytometry results for CD3 population were downsized to same number of 10 000 cells as described (SI-4 step 5). For further analysis of the 62 unmerged files (No samples obtained for 3 BL and 10 EXP LN) it was used SOM tool of FCSExpress 7. Each CD127 lowCD25 highFoxp3+ cells subpopulation (CD8, CD4, CD4+CD8+) were divided into 14 clusters (columns) as illustrated.For CD4+CD8+ CD127lowCD25highFoxp3+ cells in GILS it was observed a significant difference (p<0.001), regarding the size of cluster 2 (bold) that included a mean of 82 cells, compared with PB where the same cluster consists of only 5 (replace with 8) cells, or LN that included 8 (replace with 6) cells. In cluster 3 (bold) the differences were smaller (17 cells in GILS, compared with 1 (replace with 3) in blood (replace with PB) and 2.7 (replace with 1) in LN) but still significant (p<0.05). Likewise, for CD8+CD127lowCD25highFoxp3+ cells, the number in GILS (bold) was increased (p<0.01) in clusters 1, 3, and 5 compared with (add "PB or") LNs.. The corrected caption of table 4 appears below."[For each monkey (rows) for each corresponding sample, flow cytometry results for CD3 population were downsized to same number of 10 000 cells as described (SI-4 step 5). For further analysis of the 62 unmerged files (No samples obtained for 3 BL and 10 EXP LN) it was used SOM tool of FCSExpress 7. Each CD127lowCD25highFoxp3+ cells subpopulation (CD8, CD4, CD4+CD8+) were divided into 14 clusters (columns) as illustrated.For CD4+CD8+ CD127lowCD25highFoxp3+ cells in GILS it was observed a significant difference (p<0.001), regarding the size of cluster 2 (bold) that included a mean of 82 cells, compared with PB where the same cluster consists of only 8 cells, or LN that included 6 cells. In cluster 3 (bold) the differences were smaller (17 cells in GILS, compared with 3 in PB and 1 in LN) but still significant (p<0.05). Likewise, for CD8+CD127lowCD25highFoxp3+ cells, the number in GILS (bold) was increased (p<0.01) in clusters 1, 3, and 5 compared with PB or LNs.]"The original version of this article has been updated.
Keywords: Leucocyte dynamics, cynomolgus macaque, heart heterotopic allotransplantation, intragraft lymphocytes, T cells subpopulation
Received: 26 Oct 2025; Accepted: 03 Nov 2025.
Copyright: © 2025 Braileanu, Azimzadeh, Zhang, Burdorf and Pierson III. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Gheorghe Braileanu, gbraileanu@som.umaryland.edu
Richard N Pierson III, rpierson@mgh.harvard.edu
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