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PERSPECTIVE article

Front. Immunol.

Sec. Alloimmunity and Transplantation

Recent Progress in Pig-to-Human Kidney Xenotransplantation

Provisionally accepted
Tao  PeiTao Pei*Kaiyu  ZhouKaiyu Zhou
  • Sichuan University West China Second University Hospital, Chengdu, China

The final, formatted version of the article will be published soon.

To the editor, A significant advancement has recently been made in the transplantation of porcine kidneys to humans. For a period of 271 days, or almost nine months, the transplanted porcine kidney is functioning, and it is removed due to continuous proteinuria.

Keywords: xenotransplantation, procine kidney, 69 gene edited porcine, 271 days survival, Organ shortage

Received: 29 Oct 2025; Accepted: 24 Nov 2025.

Copyright: © 2025 Pei and Zhou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Tao Pei

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.