Frontiers in Immunology | B Cell Biology

Original Research

Published on 31 May 2024

Characterization of anti-drug antibody responses to the T-cell engaging bispecific antibody cibisatamab to understand the impact on exposure

in B Cell Biology

Gregor P. Lotz
Achim Lutz
Meret Martin-Facklam
Andre Hansbauer
Eginhard Schick
Ekkehard Moessner
Michael Antony
Thomas Stuchly
Maria Viert
Ralf J. Hosse

Frontiers in Immunology

doi 10.3389/fimmu.2024.1406353

4,244 views
3 citations

Original Research

Published on 28 May 2024

Preclinical immunogenicity risk assessment of biotherapeutics using CD4 T cell assays

in B Cell Biology

Robin E. Walsh
Angela Nix
Chloé Ackaert
Aurélie Mazy
Jana Schockaert
Sofie Pattyn
Laurent Malherbe

Frontiers in Immunology

doi 10.3389/fimmu.2024.1406040

5,476 views
2 citations

Original Research

Published on 28 May 2024

Interpretable deep learning reveals the role of an E-box motif in suppressing somatic hypermutation of AGCT motifs within human immunoglobulin variable regions

in B Cell Biology

Abhik Tambe
Thomas MacCarthy
Rushad Pavri

Frontiers in Immunology

doi 10.3389/fimmu.2024.1407470

1,682 views

Original Research

Published on 17 May 2024

IgG sialylation occurs in B cells pre antibody secretion

in B Cell Biology

Anja Werner
Maja Hanić
Olga O. Zaitseva
Gordan Lauc
Anja Lux
Lars Nitschke
Falk Nimmerjahn

Frontiers in Immunology

doi 10.3389/fimmu.2024.1402000

3,274 views
3 citations

Review

Published on 15 May 2024

Prospects for the computational humanization of antibodies and nanobodies

in B Cell Biology

Gemma L. Gordon
Matthew I. J. Raybould
Ashley Wong
Charlotte M. Deane

Frontiers in Immunology

doi 10.3389/fimmu.2024.1399438

10,182 views
13 citations

Original Research

Published on 15 May 2024

Individual and population-level variability in HLA-DR associated immunogenicity risk of biologics used for the treatment of rheumatoid arthritis

in B Cell Biology

Naonobu Sugiyama
Frances E. Terry
Andres H. Gutierrez
Toshitaka Hirano
Masato Hoshi
Yasushi Mizuno
William Martin
Shin’ichiro Yasunaga
Hiroaki Niiro
Keishi Fujio

Frontiers in Immunology

doi 10.3389/fimmu.2024.1377911

3,124 views
7 citations

Original Research

Published on 03 May 2024

Trimeric Bet v 1-specific nanobodies cause strong suppression of IgE binding

in B Cell Biology

Clarissa Bauernfeind
Ines Zettl
Tatiana Ivanova
Oksana Goryainova
Anna Marianne Weijler
Barbara Pranz
Anja Drescher
Margarete Focke-Tejkl
Tea Pavkov-Keller
Julia Eckl-Dorna

Frontiers in Immunology

doi 10.3389/fimmu.2024.1343024

7,319 views
4 citations

Original Research

Published on 26 Apr 2024

Myocardial B cells have specific gene expression and predicted interactions in dilated cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy

in B Cell Biology

Kevin C. Bermea
Carolina Duque
Charles D. Cohen
Aashik Bhalodia
Sylvie Rousseau
Jana Lovell
Marcelle Dina Zita
Monica R. Mugnier
Luigi Adamo

Frontiers in Immunology

doi 10.3389/fimmu.2024.1327372

3,613 views
3 citations

Original Research

Published on 23 Apr 2024

Simultaneous deletion of ORMDL1 and ORMDL3 proteins disrupts immune cell homeostasis

in B Cell Biology

Livia Demkova
Viktor Bugajev
Miroslava K. Adamcova
Ladislav Kuchar
Srdjan Grusanovic
Meritxell Alberich-Jorda
Petr Draber
Ivana Halova

Frontiers in Immunology

doi 10.3389/fimmu.2024.1376629

2,759 views

Review

Published on 18 Apr 2024

Exploring the depths of IgG4: insights into autoimmunity and novel treatments

in B Cell Biology

Selen Ünlü
Blanca G. Sánchez Navarro
Elif Cakan
Daniel Berchtold
Rafael Meleka Hanna
Secil Vural
Atay Vural
Andreas Meisel
Miriam L. Fichtner

Frontiers in Immunology

doi 10.3389/fimmu.2024.1346671

7,273 views
4 citations

Original Research

Published on 18 Apr 2024

Changes in the N-glycosylation of porcine immune globulin G during postnatal development

in B Cell Biology

Kristina Zlatina
Lisa Isernhagen
Christina E. Galuska
Eduard Murani
Sebastian P. Galuska

Frontiers in Immunology

doi 10.3389/fimmu.2024.1361240

1,792 views
1 citation

Original Research

Published on 18 Apr 2024

Unravelling B cell heterogeneity: insights into flow cytometry-gated B cells from single-cell multi-omics data

in B Cell Biology

Jane I. Pernes
Atheer Alsayah
Felicia Tucci
Rachael J. M. Bashford-Rogers

Frontiers in Immunology

doi 10.3389/fimmu.2024.1380386

5,610 views
2 citations

Original Research

Published on 17 Apr 2024

The ion channel TRPV5 regulates B-cell signaling and activation

in B Cell Biology

Trisha Mahtani
Hena Sheth
L. K. Smith
Leshawn Benedict
Aurelie Brecier
Nader Ghasemlou
Bebhinn Treanor

Frontiers in Immunology

doi 10.3389/fimmu.2024.1386719

2,733 views
2 citations

Original Research

Published on 04 Apr 2024

Bruton’s tyrosine kinase inhibition limits endotoxic shock by suppressing IL-6 production by marginal zone B cells in mice

in B Cell Biology

Kazuhiko Kawata
Shinya Hatano
Akemi Baba
Keisuke Imabayashi
Yoshihiro Baba

Frontiers in Immunology

doi 10.3389/fimmu.2024.1388947

2,498 views
4 citations

Review

Published on 02 Apr 2024

The role of B-1 cells in cancer progression and anti-tumor immunity

in B Cell Biology

Nely Rodríguez-Zhurbenko
Ana M. Hernández

Frontiers in Immunology

doi 10.3389/fimmu.2024.1363176

5,744 views
3 citations

Original Research

Published on 27 Mar 2024

Loss of TET2 increases B-1 cell number and IgM production while limiting CDR3 diversity

in B Cell Biology

Emily Dennis
Maria Murach
Cassidy M.R. Blackburn
Melissa Marshall
Katherine Root
Tanyaporn Pattarabanjird
Justine Deroissart
Loren D. Erickson
Christoph J. Binder
Stefan Bekiranov

Frontiers in Immunology

doi 10.3389/fimmu.2024.1380641

3,465 views
2 citations