Frontiers in Immunology | Immunological Tolerance and Regulation

Systematic Review

Published on 05 Feb 2026

Global trends of peripheral immune tolerance research: a bibliometric and visualization analysis

in Immunological Tolerance and Regulation

Shixiao Kong
Chen Lin
Yuting Shen
Jun Chen

Frontiers in Immunology

doi 10.3389/fimmu.2026.1730575

673 views

Original Research

Published on 04 Feb 2026

Disrupted immune senescence in early pregnancy is associated with recurrent pregnancy loss

in Immunological Tolerance and Regulation

Dimitar Parvanov
Rumiana Ganeva
Margarita Ruseva
Maria Handzhiyska
Lachezar Jelezarsky
Jinahn Safir
Dimitar Metodiev
Georgi Stamenov
Savina Hadjidekova

Frontiers in Immunology

doi 10.3389/fimmu.2026.1705823

299 views

Review

Accepted on 03 Feb 2026

The Role of Piezo1 in Immune Cells and Pregnancy

in Immunological Tolerance and Regulation

Yiming Fei
Yilin Liu
Lijuan Zhang

Frontiers in Immunology

Original Research

Published on 03 Feb 2026

Xuanqing Hefa formula relieves sepsis-triggered acute lung injury by targeting the NLRP3/Caspase-1 pyroptosis mechanism

in Immunological Tolerance and Regulation

Can Lei
Chunxia Zhao
Xucheng Li
Kangli Wang
Tianfen Cen
Qingquan Liu
Xiaolong Xu
Jun Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1709586

527 views

Original Research

Accepted on 02 Feb 2026

Co-delivery of endometrial mesenchymal stem cells and macrophages with an electrospun patch supresses endometrial fibrosis via IL-10 related signalling

in Immunological Tolerance and Regulation

Jiangru An
Shuhong Li
Tianyi Ma
Yonghua Chen
Paul Santerre
Wenshuang Wang
Peng Ma
Xiaoqing Zhang

Frontiers in Immunology

Editorial

Accepted on 02 Feb 2026

Editorial: HLA-G in Health and Disease: Comprehensive Insights and Future Therapeutic Directions

in Immunological Tolerance and Regulation

Jules RUSSICK
Roberta Rizzo
Ashwin Ajith

Frontiers in Immunology

Review

Accepted on 02 Feb 2026

Circular RNAs in Sepsis-Induced Acute Lung Injury: Emerging Mechanisms and Therapeutic Potential

in Immunological Tolerance and Regulation

Qinghai Liu
Yiyan Wang
Haitang Liao
Dongsheng Ren
Wenhui Guo
Jianzhong Xu
Chenyang Duan
Zhenchun Luo
Wen Jiang

Frontiers in Immunology

Original Research

Accepted on 02 Feb 2026

Dysfunctional Decidual CD2+CD4+T Cells Regulated by Rev-erbα - GFPT1 - GPI Anchored CD58 Axis of Decidual Stromal Cells Underlies Sleep Disturbance Induced Recurrent Pregnancy Loss

in Immunological Tolerance and Regulation

Songcun Wang
Mingke Qiu
Junyi Zhang
Yujie Luo
Xinhang Meng
Liyuan Cui

Frontiers in Immunology

Review

Accepted on 02 Feb 2026

Immune reprogramming in the bone marrow microenvironment: A new perspective on the bone immune microenvironment of postmenopausal osteoporosis

in Immunological Tolerance and Regulation

Xingwen Xie
Dingpeng Li
Xianli Zheng
Demin Lin
Yuan Cheng
Zhong Wang
Yangyang Chen

Frontiers in Immunology

Original Research

Accepted on 30 Jan 2026

Ascaris lumbricoides Antigen Exposure Modulates T Cell Activation via Regulation of IL-15Rα Expression, STAT5 Phosphorylation, and Promotes Differentiation of BCL6low B Cells

in Immunological Tolerance and Regulation

Giggil Pushpamithran
Daniel Söderberg Appelgren
Robert Gilman
Robert Blomgran

Frontiers in Immunology

219 views

Systematic Review

Accepted on 29 Jan 2026

Beneficial effects of a high-anthocyanin diet versus a Westernized diet on colorectal cancer risk: A systematic review

in Immunological Tolerance and Regulation

Alberto Vásquez
Paula Zúñiga
Keila Torres
Andrew F. G. Quest
Layla Simón

Frontiers in Immunology

108 views

Original Research

Published on 29 Jan 2026

Human amnion epithelial cells induce M2 macrophage polarisation partially via M-CSF secretion but independently of extracellular vesicles in vitro

in Immunological Tolerance and Regulation

Louise Zeijlon
Snehil Budhwar
Robert Lindau
Stefan Bencina
Helen Kaipe
Maria C. Jenmalm
Roberto Gramignoli
Johanna Raffetseder

Frontiers in Immunology

doi 10.3389/fimmu.2026.1723968

658 views

Review

Accepted on 26 Jan 2026

Understanding Hairy Cell Leukemia in the Context of Mature B‑ Cell Neoplasms: Tumor Microenvironment and Extracellular Vesicle contribution to disease pathogenesis

in Immunological Tolerance and Regulation

Vincenzo Ingangi
Dominga Amoroso
Eugenia Passaro
Vincenzo Di Vaia
Filippo Maltoni
Ghazal Narimanfar
Michele Minopoli
Rita Rosa
Mariateresa Ametrano
Elena Di Gennaro

Frontiers in Immunology

123 views

Original Research

Accepted on 26 Jan 2026

Cross-talk Between Lipopolysaccharide Tolerance and AGEs in the Regulation of Macrophage Inflammation and Cholesterol Efflux

in Immunological Tolerance and Regulation

Danielle Ribeiro Santos
Monique De Fatima Mello Santana
Eduarda Palanca
Milena Gomes Vancini
Sayonara Assis
Aritania S Santos
Denise Frediani Barbeiro
Suely Kunimi Kubo Ariga
Maria Lucia Cardillo Correa-Giannella
Francisco Garcia Soriano

Frontiers in Immunology

Review

Published on 22 Jan 2026

Emerging diagnostic and therapeutic opportunities in food allergy

in Immunological Tolerance and Regulation

Lukas Michaja Balsiger
Oliver M. Würgler
Hugh A. Sampson
Alexander Eggel

Frontiers in Immunology

doi 10.3389/fimmu.2025.1715845

847 views

Original Research

Published on 22 Jan 2026

Modulation of host inflammatory pathways by Pseudomonas aeruginosa extracellular vesicles in cystic fibrosis: impact of pulmonary exacerbation and elexacaftor-tezacaftor-ivacaftor treatment

in Immunological Tolerance and Regulation

Marianna Said
Aszia Burrell
Brennan Harmon
Kylie I. Krohmaly
Marina Mazur
George M. Solomon
Andrea Hahn

Frontiers in Immunology

doi 10.3389/fimmu.2026.1745853

1,310 views

Review

Published on 21 Jan 2026

From gut dysbiosis to decidual hostility: the immuno-metabolic crosstalk driving recurrent pregnancy loss

in Immunological Tolerance and Regulation

Yimin Shi
Xiufeng Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1746620

547 views

Review

Published on 20 Jan 2026

The progress of organ protection mechanisms in sepsis

in Immunological Tolerance and Regulation

Yuanjie Zhu
Junjie Cheng
Zheyang Sun
Lu Jiang
Min Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1729499

967 views

Review

Published on 20 Jan 2026

The interactions between autophagy and immune in the liver-adipose-ovary circuit of polycystic ovary syndrome

in Immunological Tolerance and Regulation

Guofeng Nie
Muxuan Liu
Luxu Yang
Chanyu Li
Chenzhao Qu
Jing Wang
Juanjuan Mei
Yanlin Wang
Lei Han
Xinwei Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1733950

661 views

Review

Published on 19 Jan 2026

Research progress on the role of MZB1 in immune regulation

in Immunological Tolerance and Regulation

Weiqi Liu
Kui Jiang
Minli Jin
Xiaochi Chen

Frontiers in Immunology

doi 10.3389/fimmu.2026.1741773

682 views

Review

Published on 16 Jan 2026

Fibroblasts as a ruler of the immune microenvironment: measurement and modulation in tissue homeostasis and disease

in Immunological Tolerance and Regulation

Yanling Zhang
Xinyi Fang
Lian Yan
Lin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1752621

933 views

Original Research

Published on 16 Jan 2026

Liu Shen Wan regulates the SPHK1/S1P axis to ameliorate influenza-induced inflammation via integrated network pharmacology and lipidomics

in Immunological Tolerance and Regulation

Biao Lei
Zhenyang Liu
Peifang Xie
Xuanxuan Li
Zhanyu Cui
Ruihan Chen
Bin Liu
Shihua Chen
Yaxin Li
Min Liang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1764754

829 views

Original Research

Published on 15 Jan 2026

Identification and validation of an endotoxin tolerance–based prognostic model with therapeutic insights in sepsis

in Immunological Tolerance and Regulation

Yu Xie
Yadong Su
Yin Qin
Qiuhong Zhang
Jie Liu
Yanlin Wu
Ning Du
Yu Jiang
Gang Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1707490

902 views

Review

Published on 15 Jan 2026

Iron homeostasis and macrophage polarization in pulmonary fibrosis: mechanisms and therapeutic perspectives

in Immunological Tolerance and Regulation

Minlan Luo
Ali Al-waqeerah
Lili Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1742761

862 views

1,658 articles

articles

Global trends of peripheral immune tolerance research: a bibliometric and visualization analysis

Disrupted immune senescence in early pregnancy is associated with recurrent pregnancy loss

The Role of Piezo1 in Immune Cells and Pregnancy

Xuanqing Hefa formula relieves sepsis-triggered acute lung injury by targeting the NLRP3/Caspase-1 pyroptosis mechanism

Co-delivery of endometrial mesenchymal stem cells and macrophages with an electrospun patch supresses endometrial fibrosis via IL-10 related signalling

Editorial: HLA-G in Health and Disease: Comprehensive Insights and Future Therapeutic Directions

Circular RNAs in Sepsis-Induced Acute Lung Injury: Emerging Mechanisms and Therapeutic Potential

Dysfunctional Decidual CD2+CD4+T Cells Regulated by Rev-erbα - GFPT1 - GPI Anchored CD58 Axis of Decidual Stromal Cells Underlies Sleep Disturbance Induced Recurrent Pregnancy Loss

Immune reprogramming in the bone marrow microenvironment: A new perspective on the bone immune microenvironment of postmenopausal osteoporosis

Ascaris lumbricoides Antigen Exposure Modulates T Cell Activation via Regulation of IL-15Rα Expression, STAT5 Phosphorylation, and Promotes Differentiation of BCL6low B Cells

Beneficial effects of a high-anthocyanin diet versus a Westernized diet on colorectal cancer risk: A systematic review

Human amnion epithelial cells induce M2 macrophage polarisation partially via M-CSF secretion but independently of extracellular vesicles in vitro

Understanding Hairy Cell Leukemia in the Context of Mature B‑ Cell Neoplasms: Tumor Microenvironment and Extracellular Vesicle contribution to disease pathogenesis

Cross-talk Between Lipopolysaccharide Tolerance and AGEs in the Regulation of Macrophage Inflammation and Cholesterol Efflux

Emerging diagnostic and therapeutic opportunities in food allergy

Modulation of host inflammatory pathways by Pseudomonas aeruginosa extracellular vesicles in cystic fibrosis: impact of pulmonary exacerbation and elexacaftor-tezacaftor-ivacaftor treatment

From gut dysbiosis to decidual hostility: the immuno-metabolic crosstalk driving recurrent pregnancy loss

The progress of organ protection mechanisms in sepsis

The interactions between autophagy and immune in the liver-adipose-ovary circuit of polycystic ovary syndrome

Research progress on the role of MZB1 in immune regulation

Fibroblasts as a ruler of the immune microenvironment: measurement and modulation in tissue homeostasis and disease

Liu Shen Wan regulates the SPHK1/S1P axis to ameliorate influenza-induced inflammation via integrated network pharmacology and lipidomics

Identification and validation of an endotoxin tolerance–based prognostic model with therapeutic insights in sepsis

Iron homeostasis and macrophage polarization in pulmonary fibrosis: mechanisms and therapeutic perspectives