Frontiers in Immunology | Immunological Tolerance and Regulation

Original Research

Accepted on 11 Jul 2025

Novel proteomics biomarkers of recurrent pregnancy loss reflect the dysregulation of immune interactions at the maternal-fetal interface

in Immunological Tolerance and Regulation

Eszter Tóth
Máté Posta
Dániel Györffy
Orsolya Oravecz
Emese Farkas
Andrea Balogh
Claudia Escher
Magdalena Bober
András Szilágyi
Petronella Hupuczi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1621168

Opinion

Accepted on 09 Jul 2025

'Immune Reset Plus': the case for combining immunotherapies to maintain self-tolerance in autoimmune diseases

in Immunological Tolerance and Regulation

Fabrina Gaspal
Parth Narendran
Sky TH Ng
Michael Price
David Cameron Wraith

Frontiers in Immunology

doi 10.3389/fimmu.2025.1634090

128 views

Mini Review

Accepted on 07 Jul 2025

Anti-IgE therapy versus allergen-specific immunotherapy for food allergy: weighing the pros and cons

in Immunological Tolerance and Regulation

Michael D Kulis
Jessica R Humphrey
James W. Krempski
Edwin Kim
Johanna M Smeekens

Frontiers in Immunology

doi 10.3389/fimmu.2025.1617153

251 views

Review

Published on 07 Jul 2025

Platelets in infection: intrinsic roles and functional outcomes

in Immunological Tolerance and Regulation

Yuwei Hu
Shuchang Dai
Congchao Qiao
Yifan Ye
Junyi Ren
Kai Wang
Ling Li
Zhong Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1616783

684 views

Original Research

Published on 07 Jul 2025

LYN and CYBB are pivotal immune and inflammatory genes as diagnostic biomarkers in recurrent spontaneous abortion

in Immunological Tolerance and Regulation

Zhuna Wu
Qiuya Lin
Zhimei Zhou
Yajing Xie
Li Huang
Liying Sheng
Qirong Shi
Yumin Ke

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568536

333 views

Brief Research Report

Accepted on 04 Jul 2025

Hyporesponsive fetus-specific T cell responses in multiparous human pregnancy

in Immunological Tolerance and Regulation

Jessica C Morgan
Grace E Hynes
Jared M Pollard
Michael S Andrade
Jong J Cheol
Anita S Chong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1634430

Editorial

Published on 02 Jul 2025

Editorial: Community series in autoantibodies, volume II

in Immunological Tolerance and Regulation

Aikaterini Kyriakou
Aikaterini Patsatsi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1644057

233 views

Review

Accepted on 26 Jun 2025

Decidual macrophage subsets and polarization puzzle during the human early pregnancy

in Immunological Tolerance and Regulation

Huiling Liu
Liping Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610891

Review

Accepted on 25 Jun 2025

Macrophages in chronic infections: regulation and remodeling

in Immunological Tolerance and Regulation

Hongle Cui
Min Wang
Sitan Jiao
Sirui Tian
Hui Liu
Bo Luo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1594988

102 views

Correction

Published on 23 Jun 2025

Correction: Investigation of potential protein biomarkers for the screening of placental-mediated fetal growth restriction disorders using targeted proteomics Olink technology

in Immunological Tolerance and Regulation

Xinyao Zhou
Wuqian Wang
Luan Chen
Yingjun Yang
Xing Wei
Jia Zhou
Kuan Sun
Ping Tang
Xiaofang Sun
Shengying Qin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1632381

647 views

Review

Published on 19 Jun 2025

Tumor necrosis factor receptor 2 in allergen tolerance: a perspective view

in Immunological Tolerance and Regulation

Guillem Montamat-Garcia
Murilo Luiz Bazon
Agnieszka Demczuk
Cathy Leonard
Markus Ollert

Frontiers in Immunology

doi 10.3389/fimmu.2025.1613719

1,075 views

Original Research

Published on 18 Jun 2025

IL-24 producing regulatory T and B lymphocytes in endometriosis

in Immunological Tolerance and Regulation

Anna Ewa Kedzierska
Daria Lorek
Anna Slawek
Mikolaj Karmowski
Aleksandra Kalota
Jaroslaw Pajak
Agnieszka Chrobak
Krzysztof Grzymajlo
Anna Chelmonska-Soyta

Frontiers in Immunology

doi 10.3389/fimmu.2025.1582762

1,143 views

Original Research

Published on 17 Jun 2025

Differential metabolic pathways underlie THC- and CBD-mediated inhibition of B-cell activation in both young and aged mice

in Immunological Tolerance and Regulation

Zhanna Yekhtin
Dmytro Petukhov
Iman Khuja
Natalya M. Kogan
Reuven Or
Osnat Almogi-Hazan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1605474

858 views

Original Research

Accepted on 16 Jun 2025

Interferon Regulatory Factor 4 dose-dependently controls peripheral Treg cell differentiation and homeostasis by modulating chromatin accessibility in mice

in Immunological Tolerance and Regulation

Leonie Caroline Voß
Constantin Schmidt
Aenne Harberts
Michael Spohn
Peter Bradtke
Alina Borchers
Stefanie Fertig
Joanna Schmid
Friedrich Koch-Nolte
Christian Krebs

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604888

187 views

Original Research

Published on 11 Jun 2025

Expression and correlation of SOCS3 and Eotaxin mRNA and proteins levels in nasal mucosal tissue of allergic rhinitis patients

in Immunological Tolerance and Regulation

Zhaopeng Kang
Lian Xu
Ping Ai
Wei Qu
Tang Li
Lixin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1561650

740 views

Editorial

Published on 10 Jun 2025

Editorial: Host-pathogen interactions during pregnancy: mechanisms of maternal and fetal immunity

in Immunological Tolerance and Regulation

Yael Alippe
Vanesa Hauk
Gil Mor
Daiana M. Vota

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629528

663 views