Frontiers in Immunology

Review

Published on 06 Nov 2025

O-GlcNAcylation-regulated classical programmed cell death in diseases: molecular crosstalk and therapeutic opportunities

in Inflammation

Runyuan Liu
Jingxuan Wei
Zhengqing Luo
Xinyi Gao
Hongshuo Zhang
Ying Kong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658769

1,433 views

Original Research

Published on 06 Nov 2025

Neutrophil gene expression in COVID-19 patients with acute respiratory distress syndrome

in Inflammation

Hiroshi Ito
Masakazu Ishikawa
Jumpei Yoshimura
Yuchen Liu
Shuhei Sakakibara
Fuminori Sugihara
Hisatake Matsumoto
Haruhiko Hirata
Hiroshi Ogura
Jun Oda

Frontiers in Immunology

doi 10.3389/fimmu.2025.1620745

2,159 views

Correction

Published on 06 Nov 2025

Correction: A systems immunology perspective on gout pathogenesis and its precision-targeted treatment strategies

in Inflammation

Zilong Chen
Qian Guo
Yanzhao Zhang
Lulu Chen
Puyu Li
Wenfei Cheng
Chuanxin Liu
Hongwei Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1713414

733 views

Review

Published on 06 Nov 2025

Immunocyte lipid metabolic reprogramming: a novel pathway for targeted intervention in autoimmune diseases

in Inflammation

Yanyu Cui
Zhendong Feng
Qihan Zhao
Haoran Dai
Yang Zheng
Hongliang Rui
Baoli Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1713148

1,692 views

Original Research

Published on 05 Nov 2025

DOCK2 as a novel CD11c ligand in neutrophils to regulate reactive oxygen species production

in Inflammation

Sophia Koutsogiannaki
Lifei Hou
Fahd Alhamdan
Mitra Mastali
Christopher Murray
Jennifer Van Eyk
Kazufumi Kunimura
Koichi Yuki

Frontiers in Immunology

doi 10.3389/fimmu.2025.1692451

1,000 views

Original Research

Published on 05 Nov 2025

Identification of glycolysis-related clusters and immune cell infiltration in hepatic fibrosis progression using machine learning models and experimental validation

in Inflammation

Guanglin Xiao
Zhiling Deng
Ke Qiu
Aoyi Li
Xingyue Yi
Hong Ren

Frontiers in Immunology

doi 10.3389/fimmu.2025.1684937

1,432 views

Review

Published on 05 Nov 2025

TNF superfamily molecules in atherosclerosis: mechanistic insights and therapeutic translation

in Inflammation

Jia Luo
Jiaying Zhang
Yunfei Xie
Mengya Wu
Zitong Wang
Di Ma

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629577

1,721 views

Original Research

Published on 04 Nov 2025

Combined complement and coagulation activation in ST-elevation myocardial infarction: associations with myocardial injury and dysfunction

in Inflammation

Karsten E. Kluge
Sigrun Halvorsen
Geir Ø. Andersen
Charlotte H. Hansen
Ingebjørg Seljeflot
Theis Tønnessen
Ida G. Lunde
Ragnhild Helseth

Frontiers in Immunology

doi 10.3389/fimmu.2025.1613603

920 views

Review

Published on 03 Nov 2025

Combatting sepsis-induced myocardial dysfunction: emerging mechanisms and immunomodulatory breakthroughs

in Inflammation

Can Liu
Hanfeng Liu
Yunxing Li
Yangxi Zeng
Xinyu Wang
Yuhan Mou
Bin Liao
Juyi Wan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1643048

2,555 views

Original Research

Published on 31 Oct 2025

HSC-derived exosomal miR-122-5p inhibits EMT and fibrosis of intrahepatic biliary epithelial cells to alleviate primary biliary cholangitis

in Inflammation

Yaqin Zhang
Ruofei Chen
Xueqing Yang
Long Qian
Bing Shen
Zongwen Shuai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1684064

1,521 views

Review

Published on 31 Oct 2025

Adipose tissue: an inflammatory organ that can not be ignored in periodontal disease related to obesity

in Inflammation

Qiqi Wang
Hongyan Li
Yu Huan
Tianyu Zhou
Jingdan Zhang
Rongkaixuan Fang
Yue Sun
Lan A
Wenzhou Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1698207

1,504 views

Opinion

Published on 30 Oct 2025

Hypothesis: platelet-rich plasma as an adjunct therapy for eczema targeting inflammation, skin barrier repair, and chronic recurrence

in Inflammation

Ju Tian
Jing Ding
Huimin You
Chunhui Ou
Hongyuan Zhu
Biao Cheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1692916

1,484 views

Review

Published on 30 Oct 2025

Electroacupuncture in non-surgical management of lumbar spinal stenosis: mechanistic potential in attenuating ligamentum flavum thickening via inflammatory factor modulation

in Inflammation

Hao-Xin Shi
Yu-Jun Gao
Shu-Ren Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1644394

1,406 views

Original Research

Published on 30 Oct 2025

Identification of novel lipid metabolism-related biomarkers of aortic dissection by integrating single-cell RNA sequencing analysis and machine learning algorithms

in Inflammation

Zhechen Li
Yusong Deng
Fei Xiao
Jiashu Sun
Qixu Zhao
Zetong Zheng
Gang Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1681989

2,456 views

Original Research

Published on 30 Oct 2025

Adipose-derived stem cell exosomes suppress NLRP3-mediated neuronal pyroptosis to attenuate seizures in a kainic acid-induced temporal lobe epilepsy model

in Inflammation

Siqi Ding
Wanying Chen
Yajun E.
Jinli Zhou
Songyun Zhao
Yanming Chen
Zhewei Dong
Hao Dai
Yucang He

Frontiers in Immunology

doi 10.3389/fimmu.2025.1691814

1,219 views

Review

Published on 30 Oct 2025

Research advances on epigenetic modifications in dendritic cells in allergic rhinitis

in Inflammation

Siyu Duan
Ziyi Jia
Leilei Zheng
Yisha Wu
Zhihan Xu
Haiyi Peng
Jinmei Xue

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682821

1,668 views

Review

Published on 29 Oct 2025

Gut–liver axis dysregulation and microbial dysbiosis in invasive liver abscess: a narrative review

in Inflammation

Xiaoshuai Bai
Zhen Wang
Kai Guo
Ping Zhou
Lei Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646893

1,487 views

Original Research

Published on 29 Oct 2025

The role of the MYL12A liquid-liquid phase separation in neutrophil improves the prognosis of acute respiratory distress syndrome: a multi-omics analysis

in Inflammation

Yufang Guo
Longjie Li
Yongjun Wang
Zexu Wang
Wei Qiu
Qian Li
Li Wang
Bing Wan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662680

1,218 views

Review

Published on 29 Oct 2025

Mast cell–neuron axis as a core mechanism in chronic pruritus of atopic dermatitis: from mechanistic insights to therapeutic targets

in Inflammation

Dongdong Li
Yusheng Han
Jingjing Zhou
Huasen Yang
Jing Chen
Hong Liang Tey
Timothy T. Y. Tan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1645095

2,961 views

Review

Published on 29 Oct 2025

Therapeutic challenges in central nervous system viral infections: advancing mesenchymal stem cell-based strategies for treating neuroinflammation and promoting tissue repair

in Inflammation

Javier Carbone-Schellman
Javiera Fontecilla-Escobar
Nicolás Sales-Salinas
William F. Chaparro-Pico
Alfredo Molina-Berríos
María Celeste Ruete
Pablo A. González
Mayra A. Machuca
Ma. Cecilia Opazo
Marcelo E. Ezquer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677433

1,643 views

Original Research

Published on 29 Oct 2025

Electrode impedance dynamics in sequential cochlear implant users: insights into cochlear immunity

in Inflammation

Logan L. Flom
Eva L. Rasche
Jacob J. Oleson
Rachel A. Scheperle
Marlan R. Hansen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1702549

1,082 views

Original Research

Published on 28 Oct 2025

A murine model of prurigo nodularis-like skin lesions induced by persistent scratching under type 2 inflammatory conditions

in Inflammation

Jiali Wu
Xiahong Li
Siqi Huang
Siyi Tang
Kaoyuan Zhang
Jiamin Yan
Xiaofan Chen
Xia Dou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1648830

1,507 views

Review

Published on 28 Oct 2025

Orchestrating inflammation: non-coding RNAs as master regulators of macrophage function in chronic obstructive pulmonary disease-an update

in Inflammation

Xinyu Yong
Xian Luo
Xiaobing Chen
Chengxiu Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1679730

1,793 views

Original Research

Published on 28 Oct 2025

Circulating NETs enable early identification of thrombotic risk in sepsis at emergency care onset

in Inflammation

Sofia Tejada
Antonio Clemente
Antonia Socias
Maria Aranda
Alberto del Castillo
Joana Mena
Joana Mª Ribas
Luisa Martín
Karla Milagritos Llerena
María Magdalena Arellano

Frontiers in Immunology

doi 10.3389/fimmu.2025.1664108

1,698 views

5,618 articles

articles

O-GlcNAcylation-regulated classical programmed cell death in diseases: molecular crosstalk and therapeutic opportunities

Neutrophil gene expression in COVID-19 patients with acute respiratory distress syndrome

Correction: A systems immunology perspective on gout pathogenesis and its precision-targeted treatment strategies

Immunocyte lipid metabolic reprogramming: a novel pathway for targeted intervention in autoimmune diseases

DOCK2 as a novel CD11c ligand in neutrophils to regulate reactive oxygen species production

Identification of glycolysis-related clusters and immune cell infiltration in hepatic fibrosis progression using machine learning models and experimental validation

TNF superfamily molecules in atherosclerosis: mechanistic insights and therapeutic translation

Combined complement and coagulation activation in ST-elevation myocardial infarction: associations with myocardial injury and dysfunction

Combatting sepsis-induced myocardial dysfunction: emerging mechanisms and immunomodulatory breakthroughs

HSC-derived exosomal miR-122-5p inhibits EMT and fibrosis of intrahepatic biliary epithelial cells to alleviate primary biliary cholangitis

Adipose tissue: an inflammatory organ that can not be ignored in periodontal disease related to obesity

Hypothesis: platelet-rich plasma as an adjunct therapy for eczema targeting inflammation, skin barrier repair, and chronic recurrence

Electroacupuncture in non-surgical management of lumbar spinal stenosis: mechanistic potential in attenuating ligamentum flavum thickening via inflammatory factor modulation

Identification of novel lipid metabolism-related biomarkers of aortic dissection by integrating single-cell RNA sequencing analysis and machine learning algorithms

Adipose-derived stem cell exosomes suppress NLRP3-mediated neuronal pyroptosis to attenuate seizures in a kainic acid-induced temporal lobe epilepsy model

Research advances on epigenetic modifications in dendritic cells in allergic rhinitis

Gut–liver axis dysregulation and microbial dysbiosis in invasive liver abscess: a narrative review

The role of the MYL12A liquid-liquid phase separation in neutrophil improves the prognosis of acute respiratory distress syndrome: a multi-omics analysis

Mast cell–neuron axis as a core mechanism in chronic pruritus of atopic dermatitis: from mechanistic insights to therapeutic targets

Therapeutic challenges in central nervous system viral infections: advancing mesenchymal stem cell-based strategies for treating neuroinflammation and promoting tissue repair

Electrode impedance dynamics in sequential cochlear implant users: insights into cochlear immunity

A murine model of prurigo nodularis-like skin lesions induced by persistent scratching under type 2 inflammatory conditions

Orchestrating inflammation: non-coding RNAs as master regulators of macrophage function in chronic obstructive pulmonary disease-an update

Circulating NETs enable early identification of thrombotic risk in sepsis at emergency care onset