Frontiers in Immunology | Molecular Innate Immunity

Original Research

Published on 11 Mar 2025

Jing-Yin-Gu-Biao formula protects mice from postinfluenza Staphylococcus aureus infection by ameliorating acute lung injury and improving hypercoagulable state via inhibiting NETosis

in Molecular Innate Immunity

Biao Lei
Jingwen Mu
Guihua Xu
Xiaodong Yang
Wenbo Huang
Liang Hu
Dan Liu
Ting Cheng
Yuhe Ma
Lirong Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567522

5,994 views
6 citations

Original Research

Published on 10 Mar 2025

Generation and characterization of a tamoxifen-inducible lineage tracing tool Cd2-P2A-CreERT2 knock-in mice

in Molecular Innate Immunity

Yang Guo
Mengyan Zhu
Zhilan Yu
Qing Li
Yanjuan Chen
Lei Ci
Ruilin Sun
Ruling Shen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1482070

4,904 views

Brief Research Report

Published on 07 Mar 2025

Effective long-term treatment with moss-produced factor H by overcoming the antibody response in a mouse model of C3G

in Molecular Innate Immunity

Todor Tschongov
Swagata Konwar
Jessika Kleindienst
Paulina Dabrowska-Schlepp
Andreas Busch
Andreas Schaaf
Christoph Schell
Manuel Rogg
Karsten Häffner

Frontiers in Immunology

doi 10.3389/fimmu.2025.1535547

2,949 views
2 citations

Review

Published on 07 Mar 2025

Immunogenicity of chondrocyte sheets: a review

in Molecular Innate Immunity

Juncen Li
Huilin Sun
Jiaqi Guan
Bohui Li
Chen Jin
Shanhong Xie
Yu Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1529384

2,486 views

Original Research

Published on 06 Mar 2025

Mechanosensitivity of macrophage polarization: comparing small molecule leukadherin-1 to substrate stiffness

in Molecular Innate Immunity

Hemant Joshi
Edgar Anaya
Anvitha Addanki
Alison Almgren-Bell
Elizabeth M. Todd
Sharon Celeste Morley

Frontiers in Immunology

doi 10.3389/fimmu.2025.1420325

4,406 views
3 citations

Original Research

Published on 05 Mar 2025

Current perspectives and trends of neutrophil extracellular traps in organ fibrosis: a bibliometric and visualization study

in Molecular Innate Immunity

Yanbo Li
Zhengmin Cao
Jing Liu
Rui Qiang
Jiuchong Wang
Wenliang Lyu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1508909

6,005 views
4 citations

Systematic Review

Published on 05 Mar 2025

Global trends and hotspots in macrophage research related to hypertension from 2015-2024: bibliometric research and visualization analysis

in Molecular Innate Immunity

Xuefei Wang
Yemao Chai
Ye Dou
Xinyi Li
Fanghe Li
Kuo Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1501432

3,743 views
2 citations

Review

Published on 04 Mar 2025

The N-formyl peptide receptors: much more than chemoattractant receptors. Relevance in health and disease

in Molecular Innate Immunity

Filomena Napolitano
Nunzia Montuori

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568629

6,597 views
7 citations

Brief Research Report

Published on 04 Mar 2025

Chromatin changes associated with neutrophil extracellular trap formation in whole blood reflect complex immune signaling

in Molecular Innate Immunity

Justin Cayford
Brandi Atteberry
Akanksha Singh-Taylor
Andrew Retter
Benjamin P. Berman
Theresa K. Kelly

Frontiers in Immunology

doi 10.3389/fimmu.2025.1515430

3,886 views
1 citation

Review

Published on 28 Feb 2025

Crosstalk between ferroptosis and innate immune in diabetic kidney disease: mechanisms and therapeutic implications

in Molecular Innate Immunity

Jinyang Wang
Haonan Shi
Ye Yang
Xueli Gong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1505794

7,470 views
8 citations

Review

Published on 28 Feb 2025

Redefining CRP in tissue injury and repair: more than an acute pro-inflammatory mediator

in Molecular Innate Immunity

Marc Potempa
Peter C. Hart
Ibraheem M. Rajab
Lawrence A. Potempa

Frontiers in Immunology

doi 10.3389/fimmu.2025.1564607

4,524 views
10 citations

Editorial

Published on 28 Feb 2025

Editorial: Methods in molecular innate immunity: 2022

in Molecular Innate Immunity

Jörg H. Fritz
Thomas A. Kufer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1576957

1,726 views

Mini Review

Published on 28 Feb 2025

The dual role of neutrophils in sepsis-associated liver injury

in Molecular Innate Immunity

Lexin Fang
Yu Song
Jiangtao Chen
Yueping Ding

Frontiers in Immunology

doi 10.3389/fimmu.2025.1538282

3,869 views
5 citations

Original Research

Published on 28 Feb 2025

Berberine hydrochloride enhances innate immunity to protect against pathogen infection via p38 MAPK pathway

in Molecular Innate Immunity

Yi Xiao
Yingwen Cui
Yan Zhang
Wenqiao Fu
Yun Liu
Fang Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1536143

4,861 views
11 citations

Review

Published on 26 Feb 2025

The sentinels of coronary artery disease: heterogeneous monocytes

in Molecular Innate Immunity

Yanyu Chen
Daya Luo
Renzhuo Gao
Jinjing Wu
Xingpeng Qiu
Yang Zou
Yingchao Jian
Shuhua Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1428978

3,703 views
1 citation

Original Research

Published on 20 Feb 2025

Single-cell analysis of CD14+CD16+ monocytes identifies a subpopulation with an enhanced migratory and inflammatory phenotype

in Molecular Innate Immunity

Vanessa Y. Ruiz
Tina M. Calderon
Rosiris Leon-Rivera
Vanessa Chilunda
Jinghang Zhang
Joan W. Berman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1475480

5,906 views
5 citations

Review

Published on 18 Feb 2025

Exploring the role of mitochondrial antiviral signaling protein in cardiac diseases

in Molecular Innate Immunity

Yuying Qi
Jie Yin
Weiwei Xia
Shiwei Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1540774

4,050 views
4 citations

Original Research

Published on 17 Feb 2025

Acute hypoxia modulate macrophage phenotype accompanied with transcriptome re-programming and metabolic re-modeling

in Molecular Innate Immunity

Binda Sun
Yao Long
Gang Xu
Jian Chen
Gang Wu
Bao Liu
Yuqi Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1534009

6,048 views
8 citations

Review

Published on 14 Feb 2025

Factor B as a therapeutic target for the treatment of complement-mediated diseases

in Molecular Innate Immunity

David Kavanagh
Jonathan Barratt
Anna Schubart
Nicholas J. A. Webb
Matthias Meier
Fadi Fakhouri

Frontiers in Immunology

doi 10.3389/fimmu.2025.1537974

13,954 views
14 citations

Mini Review

Published on 14 Feb 2025

The role of cGAS-STING pathway ubiquitination in innate immunity and multiple diseases

in Molecular Innate Immunity

Chunyan Deng
Dongyan Chen
Liang Yang
Yubiao Zhang
Cheng Jin
Yue Li
Qihong Lin
Mingjing Luo
Ruihao Zheng
Baozhen Huang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1522200

10,831 views
9 citations

Editorial

Published on 13 Feb 2025

Editorial: Immunesenescence in innate immune cells and disease development

in Molecular Innate Immunity

Rania Hassan Mohamed

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563373

1,597 views

Original Research

Published on 12 Feb 2025

Alpha-defensins increase NTHi binding but not engulfment by the macrophages enhancing airway inflammation in Alpha-1 antitrypsin deficiency

in Molecular Innate Immunity

Jungnam Lee
Naweed Mohammad
Kyudong Han
Tammy Flagg-Dowie
Maria Magallon
Mark L. Brantly
Karina A. Serban

Frontiers in Immunology

doi 10.3389/fimmu.2025.1543729

3,120 views
3 citations

Editorial

Published on 12 Feb 2025

Editorial: Impact of the innate and adaptive immune system in driving type 1 inflammatory skin disease

in Molecular Innate Immunity

Mark Mellett
Judit Danis
Barbara Meier-Schiesser

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568773

2,686 views
2 citations

Correction

Published on 12 Feb 2025

Corrigendum: Distinction of early complement classical and lectin pathway activation via quantification of C1s/C1-INH and MASP-1/C1-INH complexes using novel ELISAs

in Molecular Innate Immunity

Lisa Hurler
Erik J. M. Toonen
Erika Kajdácsi
Bregje van Bree
Ricardo J. M. G. E. Brandwijk
Wieke de Bruin
Paul A. Lyons
Laura Bergamaschi
Cambridge Institute of Therapeutic Immunology Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration
György Sinkovits

Frontiers in Immunology

doi 10.3389/fimmu.2025.1561850

1,509 views

3,597 articles

articles

Jing-Yin-Gu-Biao formula protects mice from postinfluenza Staphylococcus aureus infection by ameliorating acute lung injury and improving hypercoagulable state via inhibiting NETosis

Generation and characterization of a tamoxifen-inducible lineage tracing tool Cd2-P2A-CreERT2 knock-in mice

Effective long-term treatment with moss-produced factor H by overcoming the antibody response in a mouse model of C3G

Immunogenicity of chondrocyte sheets: a review

Mechanosensitivity of macrophage polarization: comparing small molecule leukadherin-1 to substrate stiffness

Current perspectives and trends of neutrophil extracellular traps in organ fibrosis: a bibliometric and visualization study

Global trends and hotspots in macrophage research related to hypertension from 2015-2024: bibliometric research and visualization analysis

The N-formyl peptide receptors: much more than chemoattractant receptors. Relevance in health and disease

Chromatin changes associated with neutrophil extracellular trap formation in whole blood reflect complex immune signaling

Crosstalk between ferroptosis and innate immune in diabetic kidney disease: mechanisms and therapeutic implications

Redefining CRP in tissue injury and repair: more than an acute pro-inflammatory mediator

Editorial: Methods in molecular innate immunity: 2022

The dual role of neutrophils in sepsis-associated liver injury

Berberine hydrochloride enhances innate immunity to protect against pathogen infection via p38 MAPK pathway

The sentinels of coronary artery disease: heterogeneous monocytes

Single-cell analysis of CD14+CD16+ monocytes identifies a subpopulation with an enhanced migratory and inflammatory phenotype

Exploring the role of mitochondrial antiviral signaling protein in cardiac diseases

Acute hypoxia modulate macrophage phenotype accompanied with transcriptome re-programming and metabolic re-modeling

Factor B as a therapeutic target for the treatment of complement-mediated diseases

The role of cGAS-STING pathway ubiquitination in innate immunity and multiple diseases

Editorial: Immunesenescence in innate immune cells and disease development

Alpha-defensins increase NTHi binding but not engulfment by the macrophages enhancing airway inflammation in Alpha-1 antitrypsin deficiency

Editorial: Impact of the innate and adaptive immune system in driving type 1 inflammatory skin disease

Corrigendum: Distinction of early complement classical and lectin pathway activation via quantification of C1s/C1-INH and MASP-1/C1-INH complexes using novel ELISAs