Frontiers in Immunology | Molecular Innate Immunity

Original Research

Published on 11 Mar 2024

Comparative analysis of single-cell transcriptome reveals heterogeneity and commonality in the immune microenvironment of colorectal cancer and inflammatory bowel disease

in Molecular Innate Immunity

Hongchao Lv
Yu Mu
Chen Zhang
Meiqi Zhao
Ping Jiang
Shan Xiao
Haiming Sun
Nan Wu
Donglin Sun
Yan Jin

Frontiers in Immunology

doi 10.3389/fimmu.2024.1356075

10,174 views
15 citations

Review

Published on 08 Mar 2024

Impact of particulate air pollution on airway injury and epithelial plasticity; underlying mechanisms

in Molecular Innate Immunity

Özgecan Kayalar
Hadi Rajabi
Nur Konyalilar
Deniz Mortazavi
Gizem Tuşe Aksoy
Jun Wang
Hasan Bayram

Frontiers in Immunology

doi 10.3389/fimmu.2024.1324552

11,575 views
53 citations

Case Report

Published on 08 Mar 2024

Case report: A family of atypical hemolytic uremic syndrome involving a CFH::CFHR1 fusion gene and CFHR3-1-4-2 gene duplication

in Molecular Innate Immunity

Yuko Tasaki
Hiroshi Tsujimoto
Tadafumi Yokoyama
Naotoshi Sugimoto
Shinji Kitajima
Hiroshi Fujii
Yoshihiko Hidaka
Noritoshi Kato
Shoichi Maruyama
Norimitsu Inoue

Frontiers in Immunology

doi 10.3389/fimmu.2024.1360855

4,630 views
1 citation

Review

Published on 07 Mar 2024

Crosstalk between ubiquitin ligases and ncRNAs drives cardiovascular disease progression

in Molecular Innate Immunity

Jia-Rui You
Zeng-Jin Wen
Jia-Wei Tian
Xiao-Bing Lv
Rong Li
Shu-Ping Li
Hui Xin
Pei-Feng Li
Yin-Feng Zhang
Rui Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1335519

6,410 views
4 citations

Original Research

Published on 07 Mar 2024

Mycobacterium tuberculosis-dependent monocyte expression quantitative trait loci, cytokine production, and TB pathogenesis

in Molecular Innate Immunity

Hyejeong Hong
Kimberly A. Dill-McFarland
Jason D. Simmons
Glenna J. Peterson
Penelope Benchek
Harriet Mayanja-Kizza
W. Henry Boom
Catherine M. Stein
Thomas R. Hawn

Frontiers in Immunology

doi 10.3389/fimmu.2024.1359178

6,145 views
5 citations

Review

Published on 07 Mar 2024

cGAS: action in the nucleus

in Molecular Innate Immunity

Yikai Lu
Mengmeng Zhao
Li Chen
Yan Wang
Tianhao Liu
Haipeng Liu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1380517

19,169 views
11 citations

Review

Published on 07 Mar 2024

ROS signaling in innate immunity via oxidative protein modifications

in Molecular Innate Immunity

Renuka Ramalingam Manoharan
Ankush Prasad
Pavel Pospíšil
Julia Kzhyshkowska

Frontiers in Immunology

doi 10.3389/fimmu.2024.1359600

18,911 views
92 citations

Original Research

Published on 06 Mar 2024

Unraveling the intricacies of glioblastoma progression and recurrence: insights into the role of NFYB and oxidative phosphorylation at the single-cell level

in Molecular Innate Immunity

Pulin Liu
Naifei Xing
Zhikai Xiahou
Jingwei Yan
Zhiheng Lin
Junlong Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1368685

4,925 views
51 citations

Mini Review

Published on 06 Mar 2024

Illuminating the immunological landscape: mitochondrial gene defects in pancreatic cancer through a multiomics lens

in Molecular Innate Immunity

Hao Chi
Lanqian Su
Yalan Yan
Xiang Gu
Ke Su
Han Li
Lili Yu
Jie Liu
Jue Wang
Qibiao Wu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1375143

5,233 views
13 citations

Original Research

Published on 01 Mar 2024

Comprehensive molecular and cellular characterization of endoplasmic reticulum stress-related key genes in renal ischemia/reperfusion injury

in Molecular Innate Immunity

Hao Zhang
Chaoyue Zheng
Yue Xu
Xiaopeng Hu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1340997

7,819 views
10 citations

Original Research

Published on 01 Mar 2024

TRIM28 facilitates type I interferon activation by targeting TBK1

in Molecular Innate Immunity

Fang Hua
Tim Nass
Kislay Parvatiyar

Frontiers in Immunology

doi 10.3389/fimmu.2024.1279920

7,207 views
10 citations

Original Research

Published on 01 Mar 2024

Identification of immunological patterns characterizing immune-related psoriasis reactions in oncological patients in therapy with anti-PD-1 checkpoint inhibitors

in Molecular Innate Immunity

Martina Morelli
Maria Luigia Carbone
Giovanni Luca Scaglione
Claudia Scarponi
Valentina Di Francesco
Sabatino Pallotta
Federica De Galitiis
Siavash Rahimi
Stefania Madonna
Cristina Maria Failla

Frontiers in Immunology

doi 10.3389/fimmu.2024.1346687

7,779 views
12 citations

Original Research

Published on 29 Feb 2024

SKAP2 acts downstream of CD11b/CD18 and regulates neutrophil effector function

in Molecular Innate Immunity

Panagiota Bouti
Bart J. A. M. Klein
Paul J. H. Verkuijlen
Karin Schornagel
Floris P. J. van Alphen
Kees-Karel H. Taris
Maartje van den Biggelaar
Arie J. Hoogendijk
Robin van Bruggen
Taco W. Kuijpers

Frontiers in Immunology

doi 10.3389/fimmu.2024.1344761

5,412 views
7 citations

Review

Published on 28 Feb 2024

Control of immune cell signaling by the immuno-metabolite itaconate

in Molecular Innate Immunity

Roland Lang
Md Nur A Alam Siddique

Frontiers in Immunology

doi 10.3389/fimmu.2024.1352165

16,989 views
27 citations

Editorial

Published on 27 Feb 2024

Editorial: Molecular drivers of immunothrombosis

in Molecular Innate Immunity

Alice Assinger
Madhumita Chatterjee
James D. McFadyen

Frontiers in Immunology

doi 10.3389/fimmu.2024.1385966

2,473 views
3 citations

Original Research

Published on 26 Feb 2024

Benchmarking glycoform-resolved affinity separation – mass spectrometry assays for studying FcγRIIIa binding

in Molecular Innate Immunity

Christoph Gstöttner
Steffen Lippold
Michaela Hook
Feng Yang
Markus Haberger
Manfred Wuhrer
David Falck
Tilman Schlothauer
Elena Domínguez-Vega

Frontiers in Immunology

doi 10.3389/fimmu.2024.1347871

3,648 views
8 citations

Original Research

Published on 26 Feb 2024

Neutrophil-derived Activin-A moderates their pro-NETotic activity and attenuates collateral tissue damage caused by Influenza A virus infection

in Molecular Innate Immunity

Georgios Divolis
Evgenia Synolaki
Athanasia Doulou
Ariana Gavriil
Christina C. Giannouli
Anastasia Apostolidou
Martyn L. Foster
Martin M. Matzuk
Panagiotis Skendros
Ioanna-Evdokia Galani

Frontiers in Immunology

doi 10.3389/fimmu.2024.1302489

5,581 views
7 citations

Original Research

Published on 22 Feb 2024

IL11-mediated stromal cell activation may not be the master regulator of pro-fibrotic signaling downstream of TGFβ

in Molecular Innate Immunity

Yunhao Tan
Kenta Mosallanejad
Qingxiu Zhang
Stephen O’Brien
Meghan Clements
Stuart Perper
Sarah Wilson
Sudiksha Chaulagain
Jing Wang
Mary Abdalla

Frontiers in Immunology

doi 10.3389/fimmu.2024.1293883

15,072 views
10 citations

Mini Review

Published on 22 Feb 2024

VEGFR-3 signaling in macrophages: friend or foe in disease?

in Molecular Innate Immunity

Saranya Kannan
Joseph M. Rutkowski

Frontiers in Immunology

doi 10.3389/fimmu.2024.1349500

6,366 views
14 citations

Opinion

Published on 20 Feb 2024

Exploring the ROS reduction strategies in chronic lupus management

in Molecular Innate Immunity

Kannika Parameshwari Kannan
Smiline Girija A.S.

Frontiers in Immunology

doi 10.3389/fimmu.2024.1346656

2,920 views
6 citations

Hypothesis and Theory

Published on 19 Feb 2024

Self-DNA driven inflammation in COVID-19 and after mRNA-based vaccination: lessons for non-COVID-19 pathologies

in Molecular Innate Immunity

Martin Heil

Frontiers in Immunology

doi 10.3389/fimmu.2023.1259879

20,122 views
8 citations

Original Research

Published on 16 Feb 2024

Spatial transcriptomics reveals altered lipid metabolism and inflammation-related gene expression of sebaceous glands in psoriasis and atopic dermatitis

in Molecular Innate Immunity

Peter Seiringer
Christina Hillig
Alexander Schäbitz
Manja Jargosch
Anna Caroline Pilz
Stefanie Eyerich
Andrea Szegedi
Michaela Sochorová
Florian Gruber
Christos C. Zouboulis

Frontiers in Immunology

doi 10.3389/fimmu.2024.1334844

17,588 views
30 citations

Mini Review

Published on 15 Feb 2024

Deciphering the fibrotic process: mechanism of chronic radiation skin injury fibrosis

in Molecular Innate Immunity

Yiren Wang
Shouying Chen
Shuilan Bao
Li Yao
Zhongjian Wen
Lixia Xu
Xiaoman Chen
Shengmin Guo
Haowen Pang
Yun Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2024.1338922

9,641 views
35 citations

Review

Published on 15 Feb 2024

The cGAS-STING pathway in viral infections: a promising link between inflammation, oxidative stress and autophagy

in Molecular Innate Immunity

Kunli Zhang
Qiuyan Huang
Xinming Li
Ziqiao Zhao
Chun Hong
Zeyi Sun
Bo Deng
Chunling Li
Jianfeng Zhang
Sutian Wang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1352479

13,085 views
26 citations

3,597 articles

articles

Comparative analysis of single-cell transcriptome reveals heterogeneity and commonality in the immune microenvironment of colorectal cancer and inflammatory bowel disease

Impact of particulate air pollution on airway injury and epithelial plasticity; underlying mechanisms

Case report: A family of atypical hemolytic uremic syndrome involving a CFH::CFHR1 fusion gene and CFHR3-1-4-2 gene duplication

Crosstalk between ubiquitin ligases and ncRNAs drives cardiovascular disease progression

Mycobacterium tuberculosis-dependent monocyte expression quantitative trait loci, cytokine production, and TB pathogenesis

cGAS: action in the nucleus

ROS signaling in innate immunity via oxidative protein modifications

Unraveling the intricacies of glioblastoma progression and recurrence: insights into the role of NFYB and oxidative phosphorylation at the single-cell level

Illuminating the immunological landscape: mitochondrial gene defects in pancreatic cancer through a multiomics lens

Comprehensive molecular and cellular characterization of endoplasmic reticulum stress-related key genes in renal ischemia/reperfusion injury

TRIM28 facilitates type I interferon activation by targeting TBK1

Identification of immunological patterns characterizing immune-related psoriasis reactions in oncological patients in therapy with anti-PD-1 checkpoint inhibitors

SKAP2 acts downstream of CD11b/CD18 and regulates neutrophil effector function

Control of immune cell signaling by the immuno-metabolite itaconate

Editorial: Molecular drivers of immunothrombosis

Benchmarking glycoform-resolved affinity separation – mass spectrometry assays for studying FcγRIIIa binding

Neutrophil-derived Activin-A moderates their pro-NETotic activity and attenuates collateral tissue damage caused by Influenza A virus infection

IL11-mediated stromal cell activation may not be the master regulator of pro-fibrotic signaling downstream of TGFβ

VEGFR-3 signaling in macrophages: friend or foe in disease?

Exploring the ROS reduction strategies in chronic lupus management

Self-DNA driven inflammation in COVID-19 and after mRNA-based vaccination: lessons for non-COVID-19 pathologies

Spatial transcriptomics reveals altered lipid metabolism and inflammation-related gene expression of sebaceous glands in psoriasis and atopic dermatitis

Deciphering the fibrotic process: mechanism of chronic radiation skin injury fibrosis

The cGAS-STING pathway in viral infections: a promising link between inflammation, oxidative stress and autophagy