Frontiers in Immunology | Molecular Innate Immunity

Original Research

Published on 29 Jan 2025

Functional and structural characterization of mouse Factor H-related B protein unveils a novel dimerization domain shared by FHR-B and FH

in Molecular Innate Immunity

Adrián Martín-Ambrosio Doménech
Silvia González Sanz
Bárbara Márquez Tirado
Lucia Juana-López
Elena Goicoechea de Jorge
Santiago Rodríguez de Córdoba
Héctor Martín Merinero

Frontiers in Immunology

doi 10.3389/fimmu.2025.1522651

1,064 views

Original Research

Published on 29 Jan 2025

Genetic background and microbiome drive susceptibility to epicutaneous sensitization and food allergy in adjuvant-free mouse model

in Molecular Innate Immunity

Tereza Hornikova
Anna Jelinkova
Zuzana Jiraskova Zakostelska
Tomas Thon
Stepan Coufal
Andrea Polouckova
Eliska Kopelentova
Miloslav Kverka
Peter Makovicky
Helena Tlaskalova-Hogenova

Frontiers in Immunology

doi 10.3389/fimmu.2024.1509691

2,081 views

Original Research

Published on 28 Jan 2025

IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy

in Molecular Innate Immunity

Dylan Krajewski
Saurav Ranjitkar
Nathan Jordan
Sallie S. Schneider
Clinton B. Mathias

Frontiers in Immunology

doi 10.3389/fimmu.2025.1526498

1,257 views

Original Research

Published on 24 Jan 2025

Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance

in Molecular Innate Immunity

Santiago Rodríguez de Córdoba
Andrea Reparaz
Daniel Sanchez
Sheila Pinto
Lucia Juana Lopez
Héctor Martin Merinero
Iria Calvete
Julian Perez-Perez
Sydney S. Jellison
Yuzhou Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1527016

1,603 views
2 citations

Original Research

Published on 24 Jan 2025

Ochratoxin A induces immunotoxicity by targeting Annexin A1 mediated neutrophil apoptosis in zebrafish

in Molecular Innate Immunity

Yihong Zheng
Yinuo Liu
Jin Tian
Shuhong Liu
Gaowei Ma
Yupeng Xie
Chenhua Zheng
Zekai Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1542964

1,327 views

Original Research

Published on 23 Jan 2025

Identification and validation of glycolysis-related diagnostic signatures in diabetic nephropathy: a study based on integrative machine learning and single-cell sequence

in Molecular Innate Immunity

Xiaoyin Wu
Buyu Guo
Xingyu Chang
Yuxuan Yang
Qianqian Liu
Jiahui Liu
Yichen Yang
Kang Zhang
Yumei Ma
Songbo Fu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1427626

4,852 views
1 citation

Original Research

Published on 22 Jan 2025

Nanoparticles containing intracellular proteins modulate neutrophil functional and phenotypic heterogeneity

in Molecular Innate Immunity

Leonore Raudszus
Farbod Bahreini
Susanne Allan
Kai-Uwe Kalies
Charles C. Caldwell
Kathrin Kalies

Frontiers in Immunology

doi 10.3389/fimmu.2024.1494400

2,252 views

Original Research

Published on 21 Jan 2025

A randomized, placebo-controlled trial of the BTK inhibitor zanubrutinib in hospitalized patients with COVID-19 respiratory distress: immune biomarker and clinical findings

in Molecular Innate Immunity

Steven P. Treon
Camille N. Kotton
David J. Park
Giorgia Moranzoni
Camilla K. Lemvigh
Joseph C. Gathe
Tilly A. Varughese
Christopher F. Barnett
Johnny M. Belenchia
Nina M. Clark

Frontiers in Immunology

doi 10.3389/fimmu.2024.1369619

4,329 views
1 citation

Original Research

Published on 20 Jan 2025

TLR10 overexpression modulates immune response in A549 lung epithelial cells challenged with SARS-CoV-2 S and N proteins

in Molecular Innate Immunity

Špela Knez
Mojca Narat
Jernej Ogorevc

Frontiers in Immunology

doi 10.3389/fimmu.2024.1490478

1,571 views

Review

Published on 17 Jan 2025

Macrophage-derived extracellular vesicles as new players in chronic non-communicable diseases

in Molecular Innate Immunity

Fengjuan Lin
Huiyu Luo
Jiexian Wang
Qing Li
Longying Zha

Frontiers in Immunology

doi 10.3389/fimmu.2024.1479330

2,211 views
1 citation

Original Research

Published on 17 Jan 2025

Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression of atherosclerotic plaque

in Molecular Innate Immunity

Yifeng Zhang
Shuxian Lu
Liang Qiu
Manman Qin
Dan Shan
Lianhua Xie
Yao Yi
Jun Yu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1528475

4,139 views
1 citation

Original Research

Published on 16 Jan 2025

Potential implications of granzyme B in keloids and hypertrophic scars through extracellular matrix remodeling and latent TGF-β activation

in Molecular Innate Immunity

Alexandre Aubert
Jenna Goeres
Amy Liu
Martin Kao
Katlyn C. Richardson
Karen Jung
Boris Hinz
Richard I. Crawford
David J. Granville

Frontiers in Immunology

doi 10.3389/fimmu.2024.1484462

2,379 views
1 citation

Review

Published on 14 Jan 2025

Mitochondrial dysfunction in Alzheimer’s disease: a key frontier for future targeted therapies

in Molecular Innate Immunity

Shuguang Wang
Zuning Liao
Qiying Zhang
Xinyuan Han
Changqing Liu
Jin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1484373

3,427 views
1 citation

Original Research

Published on 14 Jan 2025

A c-type lectin HcLec1 with dual function of immunology and mineralization from the freshwater oyster (Hyriopsis cumingii Lea)

in Molecular Innate Immunity

Xiaofeng Chen
Xiaoya Shen
Shijun Liu
Wenjuan Li
He Wang
Jiale Li
Zhiyi Bai

Frontiers in Immunology

doi 10.3389/fimmu.2024.1530732

919 views

Original Research

Published on 13 Jan 2025

The immune landscape of fetal chorionic villous tissue in term placenta

in Molecular Innate Immunity

Brianna M. Doratt
Heather E. True
Suhas Sureshchandra
Qi Qiao
Monica Rincon
Nicole E. Marshall
Ilhem Messaoudi

Frontiers in Immunology

doi 10.3389/fimmu.2024.1506305

2,565 views
1 citation

Review

Published on 10 Jan 2025

The role of M1/M2 macrophage polarization in the pathogenesis of obesity-related kidney disease and related pathologies

in Molecular Innate Immunity

Periklis Dousdampanis
Ioanna Aggeletopoulou
Athanasia Mouzaki

Frontiers in Immunology

doi 10.3389/fimmu.2024.1534823

4,124 views
4 citations